| Title: |
Development of a quality of life measure for left ventricular assist device recipients using a mixed methods approach |
| Authors: |
Anita L. Slade; Christel McMullan; M. Sayeed Haque; Stephen Griffith; Laura Marley; David Quinn; Margaret E. O'Hara; Mike Horton; Melanie J. Calvert; Hoong Sern Lim; Deirdre A. Lane |
| Source: |
ESC Heart Failure, Vol 11, Iss 5, Pp 3167-3179 (2024) |
| Publisher Information: |
Wiley, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
health‐related quality of life; heart failure; left ventricular assist device; patient‐reported outcomes; Rasch analysis; Diseases of the circulatory (Cardiovascular) system; RC666-701 |
| Description: |
Abstract Background Left ventricular assist device (LVAD) recipients report symptom improvement but find adjusting to life with the LVAD challenging. These challenges are unique, and existing patient‐reported outcome measures (PROMs) do not reflect their experiences. This study aimed to develop a culturally relevant quality of life PROM for use with LVAD recipients in future research, design evolutions and clinical practice. Methods A three‐stage mixed‐methods approach was used to develop a PROM: stage 1 included group concept mapping (GCM); stage 2 semi‐structured qualitative interviews were conducted with 11 LVAD recipients and 10 clinicians, and a questionnaire was developed using a conceptual framework; and stage 3 used exploratory psychometric analysis of the PROM data using Rasch measurement theory. This paper presents stages 2 and 3. Results The conceptual framework consisted of four key concepts, including general health, life with the LVAD, equipment and clothing and emotional impact. Statements from interviews and GCM were used to create items for the LVAD quality of life (LVAD‐QoL). Cognitive interviews tested face validity and participant comprehension. Forty‐nine participants were recruited from three UK transplant centres. PROM data were collected and analysed using Rasch analysis. Four items displayed misfit; dependency between item sets was the biggest issue (57/485 pairwise differences). After restructuring and dealing with item misfit, the LVAD‐QoL conformed to the Rasch model, supporting the psychometric properties and quality of the LVAD‐QoL. Conclusions Using a mixed‐methods approach ensured the development of a robust and psychometrically sound tool for research, design evolution and clinical practice with LVAD recipients. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2055-5822 |
| Relation: |
https://doaj.org/toc/2055-5822 |
| DOI: |
10.1002/ehf2.14850 |
| Access URL: |
https://doaj.org/article/8d4b7ff76d7943dba8ccca5584c7d8fa |
| Accession Number: |
edsdoj.8d4b7ff76d7943dba8ccca5584c7d8fa |
| Database: |
Directory of Open Access Journals |