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Long-term Functional, Sexual, and Cosmetic Outcomes in Adult Patients Who Underwent Hypospadias Repair During Childhood at a Highly Specialized Italian Pediatric Hospital

Title: Long-term Functional, Sexual, and Cosmetic Outcomes in Adult Patients Who Underwent Hypospadias Repair During Childhood at a Highly Specialized Italian Pediatric Hospital
Authors: Alessia Celeste Bocchino; Andrea Cocci; Marta Pezzoli; Antonio Elia; Luca Landi; Alberto Mantovani; Chiara Cini; Lorenzo Masieri
Source: Urology Research and Practice, Vol 50, Iss 2, Pp 127-133 (2024)
Publisher Information: Turkish Association of Urology, 2024.
Publication Year: 2024
Collection: LCC:Diseases of the genitourinary system. Urology
Subject Terms: Diseases of the genitourinary system. Urology; RC870-923
Description: Objective: This study aims to evaluate long-term functional, sexual, and cosmetic outcomes in adult patients who underwent hypospadias repair during childhood at a national highly specialized pediatric hospital. Methods: Medical records of pediatric patients who had undergone surgical repair of hypospadias between 1993 and 2004 at Meyer Children Hospital of Florence were reviewed. Adult patients were contacted by telephone between July and August 2021 and invited to participate. Long-term surgical outcomes were assessed focusing on complications and reinterventions, and 3 validated questionnaires on urinary function, erectile function, and penile cosmetic appearance were administered. Results: From January 1993 to December 2004, a total of 799 patients with hypospadias underwent repair surgery. Two hundred thirty-nine patients gave consent to be included in the study. Follow-ups occurred between 17 and 28 years after the first surgery. Most patients had anterior localization of hypospadias (210/239) and associated penile curvature (132/239). The most frequent surgery for hypospadias repair was meatal advancement and glanduloplasty incorporated (MAGPI) (88/239), and the most used surgical treatment for penile curvature was the Nesbit technique (49/132). The complication rate was 27% (65/239) in an average time of 4.7 years, and 48 surgical procedures have been performed to treat them. At follow-up, the mean IPSS was 0.96 ± 1.97, the mean IIEF-5 score was 24.10 ± 1.02, and the mean HOSE score was 15.47 ± 0.45. Patients who underwent reintervention reported a lower IPSS than those who underwent only 1 surgery (0.29 vs. 1.16). Conclusion: Hypospadias repair during childhood leads to rather normal urinary and sexual function and penile cosmetic appearance in adolescence and adulthood.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2980-1478
Relation: https://urologyresearchandpractice.org/en/long-term-functional-sexual-and-cosmetic-outcomes-in-adult-patients-who-underwent-hypospadias-repair-during-childhood-at-a-highly-specialized-italian-pediatric-hospital-133937; https://doaj.org/toc/2980-1478
DOI: 10.5152/tud.2024.24005
Access URL: https://doaj.org/article/f0bc510d1c604cd8ab2da660e9456a54
Accession Number: edsdoj.f0bc510d1c604cd8ab2da660e9456a54
Database: Directory of Open Access Journals