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Survey of Early Practices and Perceptions of Liver Machine Perfusion Among US Liver Transplant Surgeons

Title: Survey of Early Practices and Perceptions of Liver Machine Perfusion Among US Liver Transplant Surgeons
Authors: Michelle C. Nguyen, MD, MPH, FACS; Xingjie Li, MD; Chi Zhang, MD; Stephanie Ohara, MD; Mehrdad Motamed, MSIS; Caroline C. Jadlowiec, MD, FACS; Adyr A. Moss, MD; Kunam S. Reddy, MD; Amit K. Mathur, MD, MS, FACS
Source: Transplantation Direct, Vol 11, Iss 7, p e1841 (2025)
Publisher Information: Wolters Kluwer, 2025.
Publication Year: 2025
Collection: LCC:Surgery
Subject Terms: Surgery; RD1-811
Description: Background. Ex vivo machine perfusion (MP) has transformed organ preservation, offering significant benefits in liver transplantation (LT), particularly with high-risk donor grafts. However, adoption in the United States has been limited. We aimed to examine early adoption trends, surgeon perceptions, and barriers to implementing MP in the United States after Food and Drug Administration approval of MP platforms. Methods. A 23-question electronic survey was distributed to members of the American Society of Transplant Surgeons between October and November 2022, capturing attitudes and practices related to MP adoption. Responses from 96 surgeons representing 77 LT centers across 11 Organ Procurement and Transplantation Network regions were analyzed. Results. Forty-four respondents (48%) reported having an MP program at their institution. Adoption of MP was significantly more common in high-volume centers and those performing ≥20 donation after circulatory death (DCD) transplants annually (P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2373-8731
Relation: http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001841; https://doaj.org/toc/2373-8731
DOI: 10.1097/TXD.0000000000001841
Access URL: https://doaj.org/article/f2b4a3fdeaa14cfca6af9281317a67d4
Accession Number: edsdoj.f2b4a3fdeaa14cfca6af9281317a67d4
Database: Directory of Open Access Journals