| Title: |
Anti-Angiogenic Properties of Ginsenoside Rg3 |
| Authors: |
Nakhjavani, Maryam; Smith, E; Townsend, AR; Price, TJ; Hardingham, JE |
| Publisher Information: |
MDPI 2020-01-01 |
| Document Type: |
Electronic Resource |
| Abstract: |
Ginsenoside Rg3 (Rg3) is a member of the ginsenoside family of chemicals extracted from Panax ginseng. Like other ginsenosides, Rg3 has two epimers: 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3). Rg3 is an intriguing molecule due to its anti-cancer properties. One facet of the anti-cancer properties of Rg3 is the anti-angiogenic action. This review describes the controversies on the effects and effective dose range of Rg3, summarizes the evidence on the efficacy of Rg3 on angiogenesis, and raises the possibility that Rg3 is a prodrug |
| Index Terms: |
20(R)-ginsenoside Rg3; 20(S)-ginsenoside Rg3; angiogenesis; Biochemistry & Molecular Biology; Chemistry; Chemistry, Multidisciplinary; COLLAGEN-SYNTHESIS; ENDOTHELIAL GROWTH-FACTOR; epimer; ginsenoside Rg3; HEPATOCELLULAR-CARCINOMA; INHIBITS ANGIOGENESIS; IONIZATION MASS-SPECTROMETRY; Life Sciences & Biomedicine; NITRIC-OXIDE SYNTHASE; PANAX-GINSENG; Physical Sciences; PROSTATE-CANCER; Science & Technology; Journal Article |
| URL: |
http://hdl.handle.net/10536/DRO/DU:30159018; http://elements.deakin.edu.au/viewobject.html?id=289319&cid=1; http://doi.org/10.3390/molecules25214905; issn: 1420-3049; issn: 1420-3049; http://elements.deakin.edu.au/viewobject.html?id=289319&cid=1; http://doi.org/10.3390/molecules25214905; Molecules |
| Availability: |
Open access content. Open access content |
| Note: |
18 p.; English |
| Other Numbers: |
LD0 oai:dro.deakin.edu.au:DU:30159018; 1294077516 |
| Contributing Source: |
DEAKIN UNIV; From OAIster®, provided by the OCLC Cooperative. |
| Accession Number: |
edsoai.on1294077516 |
| Database: |
OAIster |