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Ginsenoside Rg3: Potential Molecular Targets and Therapeutic Indication in Metastatic Breast Cancer

Title: Ginsenoside Rg3: Potential Molecular Targets and Therapeutic Indication in Metastatic Breast Cancer
Authors: Nakhjavani, Maryam; Hardingham, JE; Palethorpe, HM; Tomita, Y; Smith, E; Price, TJ; Townsend, AR
Publisher Information: MDPI AG 2019-01-01
Document Type: Electronic Resource
Abstract: Breast cancer is still one of the most prevalent cancers and a leading cause of cancer death worldwide. The key challenge with cancer treatment is the choice of the best therapeutic agents with the least possible toxicities on the patient. Recently, attention has been drawn to herbal compounds, in particular ginsenosides, extracted from the root of the Ginseng plant. In various studies, significant anti-cancer properties of ginsenosides have been reported in different cancers. The mode of action of ginsenoside Rg3 (Rg3) in in vitro and in vivo breast cancer models and its value as an anti-cancer treatment for breast cancer will be reviewed
Index Terms: angiogenesis; AQP-1; breast cancer; epimer; Ginsenoside Rg3; Journal Article
URL: http://hdl.handle.net/10536/DRO/DU:30159027; http://doi.org/10.3390/medicines6010017; http://elements.deakin.edu.au/viewobject.html?id=289328&cid=1; issn: 2305-6320; issn: 2305-6320; http://doi.org/10.3390/medicines6010017; http://elements.deakin.edu.au/viewobject.html?id=289328&cid=1; Medicines
Availability: Open access content. Open access content
Note: 20 p.; English
Other Numbers: LD0 oai:dro.deakin.edu.au:DU:30159027; 1294077569
Contributing Source: DEAKIN UNIV; From OAIster®, provided by the OCLC Cooperative.
Accession Number: edsoai.on1294077569
Database: OAIster