| Title: |
Type D Personality as a Risk Factor for Adverse Outcome in Patients With Cardiovascular Disease: An Individual Patient-Data Meta-analysis |
| Authors: |
Lodder, Paul; Wicherts, Jelte M.; Antens, Marijn; Albus, Christian; Bessonov, Ivan S.; Conden, Emelie; Dulfer, Karolijn; Gostoli, Sara; Grande, Gesine; Hedberg, Par; Herrmann-Lingen, Christoph; Jaarsma, Tiny; Koo, Malcolm; Lin, Ping; Lin, Tin-Kwang; Meyer, Thomas; Pushkarev, Georgiy; Rafanelli, Chiara; Raykh, Olga I.; de Quadros, Alexandre Schaan; Schmidt, Marcia; Sumin, Alexei N.; Utens, Elisabeth M. W. J.; van Veldhuisen, Dirk J.; Wang, Yini; Kupper, Nina |
| Publisher Information: |
Linköpings universitet, Avdelningen för omvårdnad och reproduktiv hälsa Linköpings universitet, Medicinska fakulteten Tilburg Univ, Netherlands Tilburg Univ, Netherlands Tilburg Univ, Netherlands Univ Cologne, Germany; Univ Hosp, Germany Russian Acad Sci, Russia Russian Acad Sci, Russia; Uppsala Univ, Sweden Sophia Childrens Univ Hosp, Netherlands Univ Bologna, Italy Brandenburg Tech Univ Cottbus Senftenberg, Germany Uppsala Univ, Sweden Univ Gottingen, Germany; German Ctr Cardiovasc Res DZHK, Germany Tzu Chi Univ Sci & Technol, Taiwan; Univ Toronto, Canada Coll Nursing Harbin Med Univ, Peoples R China Buddhist Tzu Chi Med Fdn, Taiwan; Tzu Chi Univ, Taiwan Univ Gottingen, Germany; German Ctr Cardiovasc Res DZHK, Germany Russian Acad Sci, Russia Univ Bologna, Italy Fed State Budgetary Sci Inst Res Inst Complex Issu, Russia Univ Fdn Cardiol, Brazil Univ Fdn Cardiol, Brazil Fed State Budgetary Sci Inst Res Inst Complex Issu, Russia Amsterdam UMC Level, Netherlands Univ Groningen, Netherlands Harbin Med Univ, Peoples R China Tilburg Univ, Netherlands LIPPINCOTT WILLIAMS & WILKINS 2023 |
| Document Type: |
Electronic Resource |
| Abstract: |
ObjectiveType D personality, a joint tendency toward negative affectivity and social inhibition, has been linked to adverse events in patients with heart disease, although with inconsistent findings. Here, we apply an individual patient-data meta-analysis to data from 19 prospective cohort studies (N = 11,151) to investigate the prediction of adverse outcomes by type D personality in patients with acquired cardiovascular disease.MethodFor each outcome (all-cause mortality, cardiac mortality, myocardial infarction, coronary artery bypass grafting, percutaneous coronary intervention, major adverse cardiac event, any adverse event), we estimated type Ds prognostic influence and the moderation by age, sex, and disease type.ResultsIn patients with cardiovascular disease, evidence for a type D effect in terms of the Bayes factor (BF) was strong for major adverse cardiac event (BF = 42.5; odds ratio [OR] = 1.14) and any adverse event (BF = 129.4; OR = 1.15). Evidence for the null hypothesis was found for all-cause mortality (BF = 45.9; OR = 1.03), cardiac mortality (BF = 23.7; OR = 0.99), and myocardial infarction (BF = 16.9; OR = 1.12), suggesting that type D had no effect on these outcomes. This evidence was similar in the subset of patients with coronary artery disease (CAD), but inconclusive for patients with heart failure (HF). Positive effects were found for negative affectivity on cardiac and all-cause mortality, with the latter being more pronounced in male than female patients.ConclusionAcross 19 prospective cohort studies, type D predicts adverse events in patients with CAD, whereas evidence in patients with HF was inconclusive. In both patients with CAD and HF, we found evidence for a null effect of type D on cardiac and all-cause mortality.; Funding Agencies|European Research Council [726361] |
| Index Terms: |
type D personality; cardiovascular disease; meta-analysis; negative affectivity; cardiac events; BF = Bayes factor; CABG = coronary artery bypass grafting; CAD = coronary artery disease; CVD = cardiovascular disease; MACE = major adverse cardiac event; NA = negative affectivity; OR = odds ratio; PCI = percutaneous coronary intervention; SI = social inhibition; Psychiatry; Psykiatri; Article in journal; info:eu-repo/semantics/article; text |
| DOI: |
10.1097.PSY.0000000000001164 |
| URL: |
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-192699; Psychosomatic Medicine, 0033-3174, 2023, 85:2, s. 188-202 |
| Availability: |
Open access content. Open access content; info:eu-repo/semantics/openAccess |
| Note: |
application/pdf; English |
| Other Numbers: |
UPE oai:DiVA.org:liu-192699; 0000-0002-4197-4026; doi:10.1097/PSY.0000000000001164; PMID 36640440; ISI:000941194800010; 1428112587 |
| Contributing Source: |
UPPSALA UNIV LIBR; From OAIster®, provided by the OCLC Cooperative. |
| Accession Number: |
edsoai.on1428112587 |
| Database: |
OAIster |