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Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits

Title:	Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
Authors:	Keaton, Jacob M.^{Aff1, Aff2}; Kamali, Zoha^{Aff3, Aff4}; Xie, Tian^Aff3; Vaez, Ahmad^{Aff3, Aff4, IDs4158802401714w_cor4}; Williams, Ariel^Aff1; Goleva, Slavina B.^Aff1; Ani, Alireza^{Aff3, Aff4}; Evangelou, Evangelos^{Aff5, Aff6, Aff7}; Hellwege, Jacklyn N.^{Aff8, Aff9, Aff10}; Yengo, Loic^Aff11; Young, William J.^{Aff12, Aff13}; Traylor, Matthew^{Aff12, Aff14}; Giri, Ayush^{Aff2, Aff15}; Zheng, Zhili^{Aff11, Aff16}; Zeng, Jian^Aff11; Chasman, Daniel I.^{Aff17, Aff18}; Morris, Andrew P.^Aff19; Caulfield, Mark J.^{Aff12, Aff20}; Hwang, Shih-Jen^{Aff21, Aff22}; Kooner, Jaspal S.^Aff23; Conen, David^Aff24; Attia, John R.^Aff25; Morrison, Alanna C.^Aff26; Loos, Ruth J. F.^{Aff27, Aff28, Aff29}; Kristiansson, Kati^Aff30; Schmidt, Reinhold^Aff31; Hicks, Andrew A.^{Aff32, Aff33}; Pramstaller, Peter P.^{Aff32, Aff33}; Nelson, Christopher P.^{Aff34, Aff35}; Samani, Nilesh J.^{Aff34, Aff35}; Risch, Lorenz^{Aff36, Aff37}; Gyllensten, Ulf^Aff38; Melander, Olle^{Aff39, Aff40}; Riese, Harriette^Aff41; Wilson, James F.^{Aff42, Aff43}; Campbell, Harry^Aff42; Rich, Stephen S.^Aff44; Psaty, Bruce M.^Aff45; Lu, Yingchang^Aff46; Rotter, Jerome I.^Aff47; Guo, Xiuqing^Aff47; Rice, Kenneth M.^Aff48; Vollenweider, Peter^Aff49; Sundström, Johan^{Aff50, Aff51}; Langenberg, Claudia^{Aff52, Aff53, Aff54}; Tobin, Martin D.^{Aff55, Aff56}; Giedraitis, Vilmantas^Aff57; Luan, Jian’an^Aff52; Tuomilehto, Jaakko^{Aff30, Aff58, Aff59}; Kutalik, Zoltan^{Aff60, Aff61}; Ripatti, Samuli^{Aff62, Aff63}; Salomaa, Veikko^Aff30; Girotto, Giorgia^{Aff64, Aff65}; Trompet, Stella^{Aff66, Aff67}; Jukema, J. Wouter^{Aff67, Aff68}; van der Harst, Pim^{Aff69, Aff70}; Ridker, Paul M.^{Aff17, Aff18}; Giulianini, Franco^Aff17; Vitart, Veronique^Aff43; Goel, Anuj^{Aff71, Aff72}; Watkins, Hugh^{Aff71, Aff72}; Harris, Sarah E.^Aff73; Deary, Ian J.^Aff73; van der Most, Peter J.^Aff3; Oldehinkel, Albertine J.^Aff74; Keavney, Bernard D.^{Aff75, Aff76}; Hayward, Caroline^{Aff43, Aff77}; Campbell, Archie^{Aff77, Aff78}; Boehnke, Michael^Aff79; Scott, Laura J.^Aff79; Boutin, Thibaud^Aff43; Mamasoula, Chrysovalanto^Aff80; Järvelin, Marjo-Riitta^{Aff81, Aff82, Aff83}; Peters, Annette^{Aff84, Aff85}; Gieger, Christian^Aff86; Lakatta, Edward G.^Aff87; Cucca, Francesco^Aff88; Hui, Jennie^{Aff89, Aff90}; Knekt, Paul^Aff91; Enroth, Stefan^Aff92; De Borst, Martin H.^Aff93; Polašek, Ozren^{Aff94, Aff95}; Concas, Maria Pina^Aff65; Catamo, Eulalia^Aff65; Cocca, Massimiliano^Aff65; Li-Gao, Ruifang^Aff96; Hofer, Edith^{Aff97, Aff98}; Schmidt, Helena^Aff99; Spedicati, Beatrice^Aff64; Waldenberger, Melanie^{Aff86, Aff100}; Strachan, David P.^Aff101; Laan, Maris^Aff102; Teumer, Alexander^{Aff103, Aff104}; Dörr, Marcus^{Aff104, Aff105}; Gudnason, Vilmundur^{Aff106, Aff107}; Cook, James P.^Aff108; Ruggiero, Daniela^{Aff109, Aff110}; Kolcic, Ivana^{Aff95, Aff111}; Boerwinkle, Eric^{Aff26, Aff112}; Traglia, Michela^Aff113; Lehtimäki, Terho^{Aff114, Aff115}; Raitakari, Olli T.^{Aff116, Aff117}; Johnson, Andrew D.^{Aff21, Aff118}; Newton-Cheh, Christopher^{Aff16, Aff119}; Brown, Morris J.^Aff12; Dominiczak, Anna F.^Aff120; Sever, Peter J.^Aff121; Poulter, Neil^Aff122; Chambers, John C.^Aff123; Elosua, Roberto^{Aff124, Aff125, Aff126}; Siscovick, David^Aff127; Esko, Tõnu^Aff128; Metspalu, Andres^Aff128; Strawbridge, Rona J.^{Aff129, Aff130, Aff131}; Laakso, Markku^{Aff132, Aff133}; Hamsten, Anders^Aff131; Hottenga, Jouke-Jan^Aff134; de Geus, Eco^{Aff134, Aff135}; Morris, Andrew D.^{Aff136, Aff137}; Palmer, Colin N. A.^Aff138; Nolte, Ilja M.^Aff3; Milaneschi, Yuri^Aff139; Marten, Jonathan^Aff77; Wright, Alan^Aff77; Zeggini, Eleftheria^{Aff140, Aff141}; Howson, Joanna M. M.^{Aff14, Aff142}; O’Donnell, Christopher J.^Aff143; Spector, Tim^Aff144; Nalls, Mike A.^{Aff145, Aff146, Aff147}; Simonsick, Eleanor M.^Aff148; Liu, Yongmei^Aff149; van Duijn, Cornelia M.^Aff150; Butterworth, Adam S.^{Aff142, Aff151, Aff152, Aff153, Aff154}; Danesh, John N.^{Aff142, Aff151, Aff152, Aff153, Aff154, Aff155}; Menni, Cristina^Aff156; Wareham, Nicholas J.^Aff52; Khaw, Kay-Tee^Aff157; Sun, Yan V.^{Aff158, Aff159}; Wilson, Peter W. F.^{Aff160, Aff161}; Cho, Kelly^{Aff162, Aff163, Aff164}; Visscher, Peter M.^Aff11; Denny, Joshua C.^Aff1; Levy, Daniel^{Aff21, Aff117}; Edwards, Todd L.^{Aff2, IDs4158802401714w_cor148}; Munroe, Patricia B.^{Aff12, Aff20}; Snieder, Harold^Aff3; Warren, Helen R.^{Aff12, Aff20, IDs4158802401714w_cor151}; van Duijn, Cornelia M.^Aff150; Butterworth, Adam S.^Aff141; Vaez, Ahmad^Aff3; Teumer, Alexander^Aff103; Johnson, Andrew D.^Aff21; Morris, Andrew D.^Aff136; Peters, Annette^Aff84; Goel, Anuj^Aff71; Campbell, Archie^Aff77; Keavney, Bernard D.^Aff75; Hayward, Caroline^Aff43; Newton-Cheh, Christopher^Aff16; Nelson, Christopher P.^Aff34; Chasman, Daniel I.^Aff17; Levy, Daniel^Aff21; Ruggiero, Daniela^Aff109; de Geus, Eco^Aff134; Hofer, Edith^Aff97; Zeggini, Eleftheria^Aff140; Boerwinkle, Eric^Aff26; Girotto, Giorgia^Aff64; Warren, Helen R.^Aff12; Watkins, Hugh^Aff71; Kolcic, Ivana^Aff95; Jukema, J. Wouter^Aff67; Hui, Jennie^Aff89; Howson, Joanna M. M.^Aff14; Sundström, Johan^Aff50; Chambers, John C.^Aff122; Danesh, John N.^Aff141; Risch, Lorenz^Aff35; Caulfield, Mark J.^Aff12; Laakso, Markku^Aff132; Tobin, Martin D.^Aff55; De Borst, Martin H.^Aff92; Waldenberger, Melanie^Aff85; Samani, Nilesh J.^Aff33; Melander, Olle^Aff38; Raitakari, Olli T.^Aff115; Polašek, Ozren^Aff93; Munroe, Patricia B.^Aff12; Ridker, Paul M.^Aff17; van der Harst, Pim^Aff68; Elosua, Roberto^Aff124; Ripatti, Samuli^Aff61; Lehtimäki, Terho^Aff113; Young, William J.^Aff12; Kamali, Zoha^Aff3; Kutalik, Zoltan^Aff59
Source:	Nature Genetics. 56(5):778-791
Database:	Springer Nature Journals