Xenografted human iPSC-derived neurons with the familial Alzheimer’s disease APPV717I mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator
| Title: | Xenografted human iPSC-derived neurons with the familial Alzheimer’s disease APPV717I mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator |
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| Authors: | Qu, WenhuiAff1; Lam, MattiAff2; McInvale, Julie J.Aff1; Mares, Jason A.Aff2; Kwon, SamAff1; Humala, NelsonAff3; Mahajan, AayushiAff3; Nguyen, TrangAff1; Jakubiak, Kelly A.Aff1; Mun, Jeong-YeonAff1; Tedesco, Thomas G.Aff4; Al-Dalahmah, OsamaAff1; Hussaini, Syed A.Aff4; Sproul, Andrew A.Aff1, Aff4; Siegelin, Markus D.Aff1; De Jager, Philip L.Aff2, Aff4; Canoll, PeterAff1; Menon, VilasAff2, Aff4, IDs00401024027555_cor18; Hargus, GunnarAff1, Aff4, IDs00401024027555_cor19 |
| Source: | Acta Neuropathologica: Pathology and Mechanisms of Neurological Disease. 147(1) |
| Database: | Springer Nature Journals |