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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Title:	Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
Authors:	Evangelou, Evangelos^{Aff1, Aff2}; Warren, Helen R.^{Aff3, Aff4}; Mosen-Ansorena, David^Aff1; Mifsud, Borbala^Aff3; Pazoki, Raha^Aff1; Gao, He^{Aff1, Aff5}; Ntritsos, Georgios^Aff2; Dimou, Niki^Aff2; Cabrera, Claudia P.^{Aff3, Aff4}; Karaman, Ibrahim^Aff1; Ng, Fu Liang^Aff3; Evangelou, Marina^{Aff1, Aff6}; Witkowska, Katarzyna^Aff3; Tzanis, Evan^Aff3; Hellwege, Jacklyn N.^Aff7; Giri, Ayush^Aff8; Velez Edwards, Digna R.^Aff8; Sun, Yan V.^{Aff9, Aff10}; Cho, Kelly^{Aff11, Aff12}; Gaziano, J. Michael^{Aff11, Aff12}; Wilson, Peter W. F.^Aff13; Tsao, Philip S.^Aff14; Kovesdy, Csaba P.^Aff15; Esko, Tonu^{Aff16, Aff17}; Mägi, Reedik^Aff16; Milani, Lili^Aff16; Almgren, Peter^Aff18; Boutin, Thibaud^Aff19; Debette, Stéphanie^{Aff20, Aff21}; Ding, Jun^Aff22; Giulianini, Franco^Aff23; Holliday, Elizabeth G.^Aff24; Jackson, Anne U.^Aff25; Li-Gao, Ruifang^Aff26; Lin, Wei-Yu^Aff27; Luan, Jian’an^Aff28; Mangino, Massimo^{Aff29, Aff30}; Oldmeadow, Christopher^Aff24; Prins, Bram Peter^Aff31; Qian, Yong^Aff22; Sargurupremraj, Muralidharan^Aff21; Shah, Nabi^{Aff32, Aff33}; Surendran, Praveen^Aff27; Thériault, Sébastien^{Aff34, Aff35}; Verweij, Niek^{Aff17, Aff36, Aff37}; Willems, Sara M.^Aff28; Zhao, Jing-Hua^Aff28; Amouyel, Philippe^Aff38; Connell, John^Aff39; de Mutsert, Renée^Aff26; Doney, Alex S. F.^Aff32; Farrall, Martin^{Aff40, Aff41}; Menni, Cristina^Aff29; Morris, Andrew D.^Aff42; Noordam, Raymond^Aff43; Paré, Guillaume^Aff34; Poulter, Neil R.^Aff44; Shields, Denis C.^Aff45; Stanton, Alice^Aff46; Thom, Simon^Aff47; Abecasis, Gonçalo^Aff48; Amin, Najaf^Aff49; Arking, Dan E.^Aff50; Ayers, Kristin L.^{Aff51, Aff52}; Barbieri, Caterina M.^Aff53; Batini, Chiara^Aff54; Bis, Joshua C.^Aff55; Blake, Tineka^Aff54; Bochud, Murielle^Aff56; Boehnke, Michael^Aff25; Boerwinkle, Eric^Aff57; Boomsma, Dorret I.^Aff58; Bottinger, Erwin P.^Aff59; Braund, Peter S.^{Aff60, Aff61}; Brumat, Marco^Aff62; Campbell, Archie^{Aff63, Aff64}; Campbell, Harry^Aff65; Chakravarti, Aravinda^Aff50; Chambers, John C.^{Aff1, Aff5, Aff66, Aff67, Aff68}; Chauhan, Ganesh^Aff69; Ciullo, Marina^{Aff70, Aff71}; Cocca, Massimiliano^Aff72; Collins, Francis^Aff73; Cordell, Heather J.^Aff51; Davies, Gail^{Aff74, Aff75}; de Borst, Martin H.^Aff76; de Geus, Eco J.^Aff58; Deary, Ian J.^{Aff74, Aff75}; Deelen, Joris^Aff77; Del Greco M., Fabiola^Aff78; Demirkale, Cumhur Yusuf^Aff79; Dörr, Marcus^{Aff80, Aff81}; Ehret, Georg B.^{Aff50, Aff82}; Elosua, Roberto^{Aff83, Aff84}; Enroth, Stefan^Aff85; Erzurumluoglu, A. Mesut^Aff54; Ferreira, Teresa^{Aff86, Aff87}; Frånberg, Mattias^{Aff88, Aff89, Aff90}; Franco, Oscar H.^Aff91; Gandin, Ilaria^Aff62; Gasparini, Paolo^{Aff62, Aff72}; Giedraitis, Vilmantas^Aff92; Gieger, Christian^{Aff93, Aff94, Aff95}; Girotto, Giorgia^{Aff62, Aff72}; Goel, Anuj^{Aff40, Aff41}; Gow, Alan J.^{Aff74, Aff96}; Gudnason, Vilmundur^{Aff97, Aff98}; Guo, Xiuqing^Aff99; Gyllensten, Ulf^Aff85; Hamsten, Anders^{Aff88, Aff89}; Harris, Tamara B.^Aff100; Harris, Sarah E.^{Aff63, Aff74}; Hartman, Catharina A.^Aff101; Havulinna, Aki S.^{Aff102, Aff103}; Hicks, Andrew A.^Aff78; Hofer, Edith^{Aff104, Aff105}; Hofman, Albert^{Aff91, Aff106}; Hottenga, Jouke-Jan^Aff58; Huffman, Jennifer E.^{Aff19, Aff107, Aff108}; Hwang, Shih-Jen^{Aff107, Aff108}; Ingelsson, Erik^{Aff109, Aff110}; James, Alan^{Aff111, Aff112}; Jansen, Rick^Aff113; Jarvelin, Marjo-Riitta^{Aff1, Aff5, Aff114, Aff115, Aff116}; Joehanes, Roby^{Aff107, Aff117}; Johansson, Åsa^Aff85; Johnson, Andrew D.^{Aff107, Aff118}; Joshi, Peter K.^Aff65; Jousilahti, Pekka^Aff102; Jukema, J. Wouter^Aff119; Jula, Antti^Aff102; Kähönen, Mika^{Aff120, Aff121}; Kathiresan, Sekar^{Aff17, Aff36, Aff122}; Keavney, Bernard D.^{Aff123, Aff124}; Khaw, Kay-Tee^Aff125; Knekt, Paul^Aff102; Knight, Joanne^Aff126; Kolcic, Ivana^Aff127; Kooner, Jaspal S.^{Aff5, Aff67, Aff68, Aff128}; Koskinen, Seppo^Aff102; Kristiansson, Kati^Aff102; Kutalik, Zoltan^{Aff56, Aff129}; Laan, Maris^Aff130; Larson, Marty^Aff107; Launer, Lenore J.^Aff100; Lehne, Benjamin^Aff1; Lehtimäki, Terho^{Aff131, Aff132}; Liewald, David C. M.^{Aff74, Aff75}; Lin, Li^Aff82; Lind, Lars^Aff133; Lindgren, Cecilia M.^{Aff40, Aff87, Aff134}; Liu, YongMei^Aff135; Loos, Ruth J. F.^{Aff28, Aff59, Aff136}; Lopez, Lorna M.^{Aff74, Aff137, Aff138}; Lu, Yingchang^Aff59; Lyytikäinen, Leo-Pekka^{Aff131, Aff132}; Mahajan, Anubha^Aff40; Mamasoula, Chrysovalanto^Aff139; Marrugat, Jaume^Aff83; Marten, Jonathan^Aff19; Milaneschi, Yuri^Aff140; Morgan, Anna^Aff62; Morris, Andrew P.^{Aff40, Aff141}; Morrison, Alanna C.^Aff142; Munson, Peter J.^Aff79; Nalls, Mike A.^{Aff143, Aff144}; Nandakumar, Priyanka^Aff50; Nelson, Christopher P.^{Aff60, Aff61}; Niiranen, Teemu^{Aff102, Aff145}; Nolte, Ilja M.^Aff146; Nutile, Teresa^Aff70; Oldehinkel, Albertine J.^Aff147; Oostra, Ben A.^Aff49; O’Reilly, Paul F.^Aff148; Org, Elin^Aff16; Padmanabhan, Sandosh^{Aff64, Aff149}; Palmas, Walter^Aff150; Palotie, Aarno^{Aff103, Aff151, Aff152}; Pattie, Alison^Aff75; Penninx, Brenda W. J. H.^Aff140; Perola, Markus^{Aff102, Aff103, Aff153}; Peters, Annette^{Aff94, Aff95, Aff154}; Polasek, Ozren^{Aff127, Aff155}; Pramstaller, Peter P.^{Aff78, Aff156, Aff157}; Nguyen, Quang Tri^Aff79; Raitakari, Olli T.^{Aff158, Aff159}; Ren, Meixia^Aff160; Rettig, Rainer^Aff161; Rice, Kenneth^Aff162; Ridker, Paul M.^{Aff23, Aff163}; Ried, Janina S.^Aff94; Riese, Harriëtte^Aff147; Ripatti, Samuli^{Aff103, Aff164}; Robino, Antonietta^Aff72; Rose, Lynda M.^Aff23; Rotter, Jerome I.^Aff99; Rudan, Igor^Aff165; Ruggiero, Daniela^{Aff70, Aff71}; Saba, Yasaman^Aff166; Sala, Cinzia F.^Aff53; Salomaa, Veikko^Aff102; Samani, Nilesh J.^{Aff60, Aff61}; Sarin, Antti-Pekka^Aff103; Schmidt, Reinhold^Aff104; Schmidt, Helena^Aff166; Shrine, Nick^Aff54; Siscovick, David^Aff167; Smith, Albert V.^{Aff97, Aff98}; Snieder, Harold^Aff146; Sõber, Siim^Aff130; Sorice, Rossella^Aff70; Starr, John M.^{Aff74, Aff168}; Stott, David J.^Aff169; Strachan, David P.^Aff170; Strawbridge, Rona J.^{Aff88, Aff89}; Sundström, Johan^Aff133; Swertz, Morris A.^Aff171; Taylor, Kent D.^Aff99; Teumer, Alexander^{Aff81, Aff172}; Tobin, Martin D.^Aff54; Tomaszewski, Maciej^{Aff123, Aff124}; Toniolo, Daniela^Aff53; Traglia, Michela^Aff53; Trompet, Stella^{Aff119, Aff173}; Tuomilehto, Jaakko^{Aff174, Aff175, Aff176, Aff177}; Tzourio, Christophe^Aff21; Uitterlinden, André G.^{Aff91, Aff178}; Vaez, Ahmad^{Aff146, Aff179}; van der Most, Peter J.^Aff146; van Duijn, Cornelia M.^Aff49; Vergnaud, Anne-Claire^Aff1; Verwoert, Germaine C.^Aff91; Vitart, Veronique^Aff19; Völker, Uwe^{Aff81, Aff180}; Vollenweider, Peter^Aff181; Vuckovic, Dragana^{Aff62, Aff182}; Watkins, Hugh^{Aff40, Aff41}; Wild, Sarah H.^Aff183; Willemsen, Gonneke^Aff58; Wilson, James F.^{Aff19, Aff65}; Wright, Alan F.^Aff19; Yao, Jie^Aff99; Zemunik, Tatijana^Aff184; Zhang, Weihua^{Aff1, Aff67}; Attia, John R.^Aff24; Butterworth, Adam S.^{Aff27, Aff185}; Chasman, Daniel I.^{Aff23, Aff163}; Conen, David^{Aff186, Aff187}; Cucca, Francesco^{Aff188, Aff189}; Danesh, John^{Aff27, Aff185}; Hayward, Caroline^Aff19; Howson, Joanna M. M.^Aff27; Laakso, Markku^Aff190; Lakatta, Edward G.^Aff191; Langenberg, Claudia^Aff28; Melander, Olle^Aff18; Mook-Kanamori, Dennis O.^{Aff26, Aff192}; Palmer, Colin N. A.^Aff32; Risch, Lorenz^{Aff193, Aff194, Aff195}; Scott, Robert A.^Aff28; Scott, Rodney J.^Aff24; Sever, Peter^Aff128; Spector, Tim D.^Aff29; van der Harst, Pim^Aff196; Wareham, Nicholas J.^Aff28; Zeggini, Eleftheria^Aff31; Levy, Daniel^{Aff107, Aff118}; Munroe, Patricia B.^{Aff3, Aff4}; Newton-Cheh, Christopher^{Aff134, Aff197, Aff198}; Brown, Morris J.^{Aff3, Aff4}; Metspalu, Andres^Aff16; Hung, Adriana M.^Aff199; O’Donnell, Christopher J.^Aff200; Edwards, Todd L.^Aff7; Psaty, Bruce M.^{Aff202, Aff203}; Tzoulaki, Ioanna^{Aff1, Aff2, Aff5}; Barnes, Michael R.^{Aff3, Aff4}; Wain, Louise V.^{Aff54, Aff61}; Elliott, Paul^{Aff1, Aff5, Aff204, Aff205, Aff206, cor1}; Caulfield, Mark J.^{Aff3, Aff4, cor2}
Source:	Nature Genetics. 50(10):1412-1425
Database:	Springer Nature Journals