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Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

Title:	Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
Authors:	Reiman, Eric M.^{Aff1, Aff2, Aff3, Aff4, IDs41467019142798_cor1}; Arboleda-Velasquez, Joseph F.^Aff5; Quiroz, Yakeel T.^Aff6; Huentelman, Matthew J.^Aff4; Beach, Thomas G.^Aff1; Caselli, Richard J.^Aff7; Chen, Yinghua^Aff1; Su, Yi^Aff1; Myers, Amanda J.^Aff8; Hardy, John^Aff9; Paul Vonsattel, Jean^Aff10; Younkin, Steven G.^Aff11; Bennett, David A.^Aff12; De Jager, Philip L.^Aff13; Larson, Eric B.^Aff14; Crane, Paul K.^Aff15; Keene, C. Dirk^Aff16; Kamboh, M. Ilyas^Aff17; Kofler, Julia K.^Aff18; Duque, Linda^Aff19; Gilbert, John R.^Aff20; Gwirtsman, Harry E.^Aff21; Buxbaum, Joseph D.^Aff22; Dickson, Dennis W.^Aff23; Frosch, Matthew P.^Aff24; Ghetti, Bernardino F.^Aff25; Lunetta, Kathryn L.^Aff26; Wang, Li-San^Aff27; Hyman, Bradley T.^Aff28; Kukull, Walter A.^Aff29; Foroud, Tatiana^Aff30; Haines, Jonathan L.^Aff31; Mayeux, Richard P.^Aff32; Pericak-Vance, Margaret A.^Aff20; Schneider, Julie A.^Aff12; Trojanowski, John Q.^Aff27; Farrer, Lindsay A.^{Aff26, Aff33, Aff34, Aff35}; Schellenberg, Gerard D.^Aff27; Beecham, Gary W.^Aff20; Montine, Thomas J.^Aff36; Jun, Gyungah R.^Aff33; Abner, Erin^Aff37; Adams, Perrie M.^Aff38; Albert, Marilyn S.^Aff39; Albin, Roger L.^{Aff40, Aff41, Aff42, Aff43, Aff44, Aff45, Aff46}; Apostolova, Liana G.^{Aff43, Aff44, Aff45, Aff46, Aff47}; Arnold, Steven E.^Aff48; Asthana, Sanjay^{Aff49, Aff50, Aff51}; Atwood, Craig S.^{Aff49, Aff50, Aff51}; Baldwin, Clinton T.^Aff33; Barber, Robert C.^Aff52; Barnes, Lisa L.^{Aff12, Aff18}; Barral, Sandra^Aff32; Becker, James T.^Aff53; Beekly, Duane^Aff54; Bigio, Eileen H.^{Aff55, Aff56}; Bird, Thomas D.^{Aff57, Aff58}; Blacker, Deborah^{Aff5, Aff59}; Boeve, Bradley F.^Aff60; Bowen, James D.^Aff61; Boxer, Adam^Aff62; Burke, James R.^Aff63; Burns, Jeffrey M.^Aff64; Cairns, Nigel J.^Aff65; Cantwell, Laura B.^Aff27; Cao, Chuanhai^Aff66; Carlson, Chris S.^Aff67; Carlsson, Cynthia M.^{Aff49, Aff50, Aff51}; Carney, Regina M.^Aff8; Carrasquillo, Minerva M.^Aff23; Chui, Helena C.^Aff68; Cribbs, David H.^Aff69; Crocco, Elizabeth A.^Aff8; Cruchaga, Carlos^Aff70; DeCarli, Charles^Aff71; Dick, Malcolm^Aff72; Doody, Rachelle S.^Aff73; Duara, Ranjan^Aff74; Ertekin-Taner, Nilufer^{Aff11, Aff23}; Evans, Denis A.^Aff75; Faber, Kelley M.^Aff47; Fairchild, Thomas J.^Aff76; Fallon, Kenneth B.^Aff77; Fardo, David W.^Aff78; Farlow, Martin R.^Aff79; Ferris, Steven^Aff80; Galasko, Douglas R.^Aff81; Gearing, Marla^{Aff82, Aff83}; Geschwind, Daniel H.^Aff84; Ghisays, Valentina^Aff1; Goate, Alison M.^Aff22; Graff-Radford, Neill R.^{Aff11, Aff23}; Green, Robert C.^Aff85; Growdon, John H.^Aff28; Hakonarson, Hakon^Aff86; Hamilton, Ronald L.^Aff18; Hamilton-Nelson, Kara L.^Aff20; Harrell, Lindy E.^Aff87; Honig, Lawrence S.^Aff32; Huebinger, Ryan M.^Aff88; Hulette, Christine M.^Aff89; Jarvik, Gail P.^{Aff90, Aff91}; Jin, Lee-Way^Aff92; Karydas, Anna^Aff62; Katz, Mindy J.^Aff93; Kauwe, John S. K.^Aff94; Kaye, Jeffrey A.^{Aff95, Aff96}; Kim, Ronald^Aff97; Kowall, Neil W.^{Aff34, Aff98}; Kramer, Joel H.^Aff99; Kunkle, Brian W.^Aff20; Kuzma, Amanda P.^Aff27; LaFerla, Frank M.^Aff100; Lah, James J.^Aff101; Leung, Yuk Ye^Aff27; Leverenz, James B.^Aff102; Levey, Allan I.^Aff101; Li, Ge^{Aff58, Aff103}; Lieberman, Andrew P.^Aff104; Lipton, Richard B.^Aff93; Lopez, Oscar L.^Aff17; Lyketsos, Constantine G.^Aff105; Malamon, John^Aff27; Marson, Daniel C.^Aff87; Martin, Eden R.^Aff20; Martiniuk, Frank^Aff106; Mash, Deborah C.^Aff19; Masliah, Eliezer^{Aff81, Aff107}; McCormick, Wayne C.^Aff15; McCurry, Susan M.^Aff108; McDavid, Andrew N.^Aff67; McDonough, Stefan^Aff109; McKee, Ann C.^{Aff34, Aff98}; Mesulam, Marsel^{Aff56, Aff110}; Miller, Bruce L.^Aff62; Miller, Carol A.^Aff111; Miller, Joshua W.^Aff92; Morris, John C.^{Aff65, Aff112}; Mukherjee, Shubhabrata^Aff15; Naj, Adam C.^Aff27; O’Bryant, Sid^Aff113; Olichney, John M.^Aff71; Parisi, Joseph E.^Aff114; Paulson, Henry L.^Aff115; Peskind, Elaine^Aff103; Petersen, Ronald C.^Aff60; Pierce, Aimee^Aff69; Poon, Wayne W.^Aff72; Potter, Huntington^Aff116; Qu, Liming^Aff27; Quinn, Joseph F.^{Aff95, Aff96}; Raj, Ashok^Aff44; Raskind, Murray^Aff103; Reisberg, Barry^{Aff80, Aff117}; Reisch, Joan S.^Aff118; Reitz, Christiane^{Aff32, Aff119}; Ringman, John M.^Aff68; Roberson, Erik D.^Aff87; Rogaeva, Ekaterina^Aff120; Rosen, Howard J.^Aff62; Rosenberg, Roger N.^Aff121; Royall, Donald R.^Aff122; Sager, Mark A.^Aff50; Sano, Mary^Aff22; Saykin, Andrew J.^{Aff43, Aff44}; Schneider, Lon S.^{Aff68, Aff123}; Seeley, William W.^Aff62; Smith, Amanda G.^Aff66; Sonnen, Joshua A.^Aff16; Spina, Salvatore^Aff25; George-Hyslop, Peter St^{Aff120, Aff124}; Stern, Robert A.^Aff34; Swerdlow, Russell H.^Aff64; Tanzi, Rudolph E.^Aff28; Troncoso, Juan C.^Aff125; Tsuang, Debby W.^{Aff58, Aff103}; Valladares, Otto^Aff27; Van Deerlin, Vivianna M.^Aff27; Van Eldik, Linda J.^Aff126; Vardarajan, Badri N.^Aff32; Vinters, Harry V.^{Aff127, Aff128}; Weintraub, Sandra^{Aff55, Aff56}; Welsh-Bohmer, Kathleen A.^{Aff47, Aff63}; Wilhelmsen, Kirk C.^Aff129; Williamson, Jennifer^Aff32; Wingo, Thomas S.^Aff101; Woltjer, Randall L.^Aff130; Wright, Clinton B.^Aff131; Wu, Chuang-Kuo^Aff132; Yu, Chang-En^Aff15; Yu, Lei^Aff12; Zhao, Yi^Aff27
Source:	Nature Communications. 11(1)
Database:	Springer Nature Journals