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Treffer 1 - 25 von 685, Suchdauer: 1.3s

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1
Development of a camelid single-domain antibody-based antigen detection assay for the pan-specific diagnosis of active human and animal Trypanosoma brucei infections

von Zeng Li ; Bo-kyung Jin ; Emily Estefania Timaury Moreno ; et al.

Journal of Clinical Microbiology, Vol 63, Iss 12 (2025)

Schlagworte: Trypanosoma brucei; single-domain antibody; enolase; diagnosis; sandwich ELISA assay; Microbiology; QR1-502
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2
IL-10 Plays a Critical Role in Mitigating Acute Anaemia Development During African Trypanosome Infection

von Maida Živalj ; Anaïs St. Martin ; Patrick De Baetselier ; et al.

Pathogens, Vol 14, Iss 12, p 1276 (2025)

Schlagworte: IL-10; erythropoiesis; anaemia; IFN-γ; central macrophage; Medicine
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3
A CRISPR-Cas-based recombinase polymerase amplification assay for ultra-sensitive detection of active Trypanosoma brucei evansi infections

von Andrés Álvarez-Rodríguez ; Zeng Li ; Bo-Kyung Jin ; et al.

Frontiers in Molecular Biosciences, Vol 12 (2025)

Schlagworte: Trypanosoma brucei evansi; Surra; CRISPR-Cas; RPA; diagnosis; Biology (General); QH301-705.5
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4
Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids

von Benoit Stijlemans ; Patrick De Baetselier ; Inge Van Molle ; et al.

Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Schlagworte: Science
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5
Beyond the VSG layer: Exploring the role of intrinsic disorder in the invariant surface glycoproteins of African trypanosomes.

von Hagen Sülzen ; Alexander N Volkov ; Rob Geens ; et al.

PLoS Pathogens, Vol 20, Iss 4, p e1012186 (2024)

Schlagworte: Immunologic diseases. Allergy; RC581-607; Biology (General); QH301-705.5
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6
Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments

von Michel, Maurice ; Stijlemans, Benoit ; Michel, Dana ; et al.

Glycoconjugate Journal: Official Journal of the International Glycoconjugate Organization. 42(34):147-158
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7
The Role of MIF and IL-10 as Molecular Yin-Yang in the Modulation of the Host Immune Microenvironment During Infections: African Trypanosome Infections as a Paradigm

von Benoit Stijlemans ; Maxime Schoovaerts ; Patrick De Baetselier ; et al.

Frontiers in Immunology, Vol 13 (2022)

Schlagworte: MIF; IL-10; glucocorticoids; African trypanosomiasis; T. brucei; T. congolense; Immunologic diseases. Allergy; RC581-607
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8
Immunogenicity Risk Profile of Nanobodies

von Chloé Ackaert ; Natalia Smiejkowska ; Catarina Xavier ; et al.

Frontiers in Immunology, Vol 12 (2021)

Schlagworte: nanobody; immunogenicity; anti drug antibodies; dendritic cells; T cell—DC interactions; DC activation; Immunologic diseases. Allergy; RC581-607
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9
A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute Experimental Trypanosoma brucei Infection

von Carl De Trez ; Benoit Stijlemans ; Viki Bockstal ; et al.

Frontiers in Immunology, Vol 11 (2020)

Schlagworte: T. brucei; IL-10; inflammation; T cells; IL-27; Blimp-1; Immunologic diseases. Allergy; RC581-607
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10
Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection.

von Benoit Stijlemans ; Hannelie Korf ; Patrick De Baetselier ; et al.

PLoS Pathogens, Vol 16, Iss 2, p e1008170 (2020)

Schlagworte: Immunologic diseases. Allergy; RC581-607; Biology (General); QH301-705.5
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11
Development of a recombinase polymerase amplification lateral flow assay for the detection of active Trypanosoma evansi infections.

von Zeng Li ; Joar Esteban Pinto Torres ; Julie Goossens ; et al.

PLoS Neglected Tropical Diseases, Vol 14, Iss 2, p e0008044 (2020)

Schlagworte: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270
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12
African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System

von Benoit Stijlemans ; Patrick De Baetselier ; Stefan Magez ; et al.

Frontiers in Immunology, Vol 9 (2018)

Schlagworte: anemia; MPS; MIF; erythrophagocytosis; inflammation; hemodilution; Immunologic diseases. Allergy; RC581-607
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13
Nanobodies As Tools to Understand, Diagnose, and Treat African Trypanosomiasis

von Benoit Stijlemans ; Patrick De Baetselier ; Guy Caljon ; et al.

Frontiers in Immunology, Vol 8 (2017)

Schlagworte: nanobody; diagnosis; treatment; African trypanosomes; paratransgenesis; Immunologic diseases. Allergy; RC581-607
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14
A New Family of Diverse Skin Peptides from the Microhylid Frog Genus Phrynomantis

von Constantijn Raaymakers ; Benoit Stijlemans ; Charlotte Martin ; et al.

Molecules, Vol 25, Iss 4, p 912 (2020)

Schlagworte: amphibians; frogs; microhylidae; poison; peptides; evolution; Organic chemistry; QD241-441
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15
The Trypanosomal Transferrin Receptor of Trypanosoma Brucei—A Review

von Christopher K. Kariuki ; Benoit Stijlemans ; Stefan Magez

Tropical Medicine and Infectious Disease, Vol 4, Iss 4, p 126 (2019)

Schlagworte: trypanosomosis; iron; transferrin; transferrin receptor; nutritional immunity; flagellar pocket; Medicine
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16
African Trypanosomes Undermine Humoral Responses and Vaccine Development: Link with Inflammatory Responses?

von Benoit Stijlemans ; Magdalena Radwanska ; Carl De Trez ; et al.

Frontiers in Immunology, Vol 8 (2017)

Schlagworte: B-cell lymphopoiesis; African trypanosomosis; vaccination strategies; inflammation; T-cells; macrophage migration inhibitory factor (MIF); Immunologic diseases. Allergy; RC581-607
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17
MIF inhibition interferes with the inflammatory and T cell-stimulatory capacity of NOD macrophages and delays autoimmune diabetes onset.

von Hannelie Korf ; Laura Breser ; Jelter Van Hoeck ; et al.

PLoS ONE, Vol 12, Iss 11, p e0187455 (2017)

Schlagworte: Medicine; Science
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18
The Possible Role of Staphylococcus epidermidis LPxTG Surface Protein SesC in Biofilm Formation.

von Laleh Khodaparast ; Ladan Khodaparast ; Mohammad Shahrooei ; et al.

PLoS ONE, Vol 11, Iss 1, p e0146704 (2016)

Schlagworte: Medicine; Science
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19
NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia.

von Jennifer Cnops ; Carl De Trez ; Benoit Stijlemans ; et al.

PLoS Pathogens, Vol 11, Iss 6, p e1004964 (2015)

Schlagworte: Immunologic diseases. Allergy; RC581-607; Biology (General); QH301-705.5
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20
Murine Liver Myeloid Cell Isolation Protocol

von Benoit Stijlemans ; Amanda Sparkes ; Chloé Abels ; et al.

Bio-Protocol, Vol 5, Iss 10 (2015)

Schlagworte: Biology (General); QH301-705.5
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21
Development of a pHrodo-based assay for the assessment of in vitro and in vivo erythrophagocytosis during experimental trypanosomosis.

von Benoit Stijlemans ; Jennifer Cnops ; Peter Naniima ; et al.

PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003561 (2015)

Schlagworte: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270
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22
Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes.

von Emmanuel Obishakin ; Benoit Stijlemans ; Julien Santi-Rocca ; et al.

PLoS ONE, Vol 9, Iss 12, p e115893 (2014)

Schlagworte: Medicine; Science
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23
Low structural variation in the host-defense peptide repertoire of the dwarf clawed frog Hymenochirus boettgeri (Pipidae).

von Severine Matthijs ; Lumeng Ye ; Benoit Stijlemans ; et al.

PLoS ONE, Vol 9, Iss 1, p e86339 (2014)

Schlagworte: Medicine; Science
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24
Origin and functional diversification of an amphibian defense peptide arsenal.

von Kim Roelants ; Bryan G Fry ; Lumeng Ye ; et al.

PLoS Genetics, Vol 9, Iss 8, p e1003662 (2013)

Schlagworte: Genetics; QH426-470
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25
Targeting the tsetse-trypanosome interplay using genetically engineered Sodalis glossinidius.

von Linda De Vooght ; Karin De Ridder ; Shahid Hussain ; et al.

PLoS Pathogens, Vol 18, Iss 3, p e1010376 (2022)

Schlagworte: Immunologic diseases. Allergy; RC581-607; Biology (General); QH301-705.5
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