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1
Plasma p-tau217 and tau-PET predict future cognitive decline among cognitively unimpaired individuals: implications for clinical trials

von Ossenkoppele, R ; Salvadó, G ; Janelidze, S ; et al.
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2
MRI Distance Measures as a Predictor of Subsequent Clinical Status During the Preclinical Phase of Alzheimer's Disease and Related Disorders

von Zhang, X ; Caffo, BS ; Soldan, A ; et al.
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3
Regional effects of gantenerumab on neuroimaging biomarkers in the DIAN-TU-001 trial

von McCullough, A ; Chen, CD ; Gordon, BA ; et al.
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4
Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex

von Ossenkoppele, R ; Coomans, EM ; Apostolova, LG ; et al.
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5
Machine learning reveals distinct neuroanatomical signatures of cardiovascular and metabolic diseases in cognitively unimpaired individuals

von Govindarajan, ST ; Mamourian, E ; Erus, G ; et al.
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6
Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial

von Bateman, RJ ; Li, Y ; McDade, EM ; et al.

The Lancet Neurology , 24 (4) pp. 316-330. (2025)
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7
Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia

von Llibre-Guerra, JJ ; Fernandez, MV ; Joseph-Mathurin, N ; et al.

Nature Medicine , 31 (4) pp. 1267-1275. (2025)

Schlagworte: Science & Technology; Life Sciences & Biomedicine; Biochemistry & Molecular Biology; Cell Biology; Medicine; Research & Experimental; Research & Experimental Medicine; TREM2 VARIANTS; TAU PATHOLOGY; ONSET; GENE
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8
Plasma Phosphorylated Tau 217 to Identify Preclinical Alzheimer Disease

von Salvadó, G ; Janelidze, S ; Bali, D ; et al.
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9
Identifying individuals with non-Alzheimer's disease co-pathologies: A precision medicine approach to clinical trials in sporadic Alzheimer's disease

von Tosun, D ; Yardibi, O ; Benzinger, TLS ; et al.
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10
Axonal damage and inflammation response are biological correlates of decline in small-world values: a cohort study in autosomal dominant Alzheimer’s disease

von Vermunt, L ; Sutphen, CL ; Dicks, E ; et al.
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11
Evolution of white matter hyperintensity segmentation methods and implementation over the past two decades; an incomplete shift towards deep learning

von Rahmani, M ; Dierker, D ; Yaeger, L ; et al.
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12
Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering

von Yang, Z ; Wen, J ; Abdulkadir, A ; et al.
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13
Accuracy of TrUE-Net in comparison to established white matter hyperintensity segmentation methods: An independent validation study

von Strain, JF ; Rahmani, M ; Dierker, D ; et al.
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14
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease

von Delvenne, A ; Gobom, J ; Schindler, SE ; et al.
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15
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease The DIAN-TU-001 Randomized Clinical Trial

von Wagemann, O ; Liu, H ; Wang, G ; et al.

JAMA Neurology (2024) (In press).

Schlagworte: Dominantly Inherited Alzheimer Network–Trials Unit
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16
Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease

von Wang, G ; Li, Y ; Xiong, C ; et al.

Alzheimer's and Dementia (2024) (In press).

Schlagworte: Dominantly Inherited Alzheimer Network; autosomal dominant Alzheimer's disease; gantenerumab; latent class analysis; solanezumab; surrogate biomarker
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17
γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)

von Schultz, SA ; Liu, L ; Schultz, AP ; et al.

The Lancet Neurology , 23 (9) pp. 913-924. (2024)
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18
Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

von Wisch, JK ; McKay, NS ; Boerwinkle, AH ; et al.

The Lancet Neurology , 23 (5) pp. 500-510. (2024)
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19
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)

von McKay, NS ; Gordon, BA ; Hornbeck, RC ; et al.
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20
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease

von Johnson, ECB ; Bian, S ; Haque, RU ; et al.

Nature Medicine , 29 pp. 1979-1988. (2023)

Schlagworte: Alzheimer's disease; Diagnostic markers
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21
Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease

von Schultz, SA ; Shirzadi, Z ; Schultz, AP ; et al.

Aging Cell , Article e13871. (2023)

Schlagworte: PSEN1; Presenilin-1; Autosomal dominant Alzheimer disease (ADAD); heterogeneity; neurodegeneration
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22
Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease

von Shirzadi, Z ; Schultz, SA ; Yau, WYW ; et al.

JAMA Neurology , 80 (12) pp. 1353-1363. (2023)
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23
Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease

von Llibre-Guerra, JJ ; Iaccarino, L ; Coble, D ; et al.

Brain Communications , 5 (6) , Article fcad280. (2023)

Schlagworte: dominantly inherited; early-onset Alzheimer’s disease; sporadic
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24
T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease

von Rahmani, F ; Brier, MR ; Gordon, BA ; et al.

Human Brain Mapping (2023) (In press).

Schlagworte: T1 and FLAIR signal intensity; amyloid PET; dominantly inherited Alzheimer disease; quantitative MR imaging; tau PET
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25
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von Ossenkoppele, R ; Coomans, EM ; Apostolova, LG ; et al.

Schlagworte: Journal Article
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