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1
Germline variants of the POLH and RAD51 genes are candidate variants associated with risk of hormone receptor-negative young-onset breast cancer

von Shu Yazaki ; Rui Kitadai ; Yukihide Momozawa ; et al.

npj Breast Cancer, Vol 11, Iss 1, Pp 1-11 (2025)

Schlagworte: Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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2
Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

von Youngjune Bhak ; Vasilis Raptis ; Yunye He ; et al.

Scientific Reports, Vol 15, Iss 1, Pp 1-16 (2025)

Schlagworte: Proteome profiles; Sex-dimorphic protein quantitative trait loci; Sex differences; Medicine; Science
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3
Association of circulating metabolites and polygenic risk score with incident type 2 diabetes: a prospective community-based cohort study

von Masato Takase ; Naoki Nakaya ; Mana Kogure ; et al.

Cardiovascular Diabetology, Vol 24, Iss 1, Pp 1-19 (2025)

Schlagworte: Type 2 diabetes; Genetic; Metabolomics; Personalized prevention; Diseases of the circulatory (Cardiovascular) system; RC666-701
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4
A variant in HMMR/HMMR-AS1 is associated with serum alanine aminotransferase levels in the Ryukyu population

von Noriko Ohyama ; Masatoshi Matsunami ; Minako Imamura ; et al.

Scientific Reports, Vol 15, Iss 1, Pp 1-10 (2025)

Schlagworte: Genome-wide association study; Japanese population; Ryukyu population; Alanine aminotransferase; HMMR; HMMR-AS1; Medicine; Science
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5
Genetic regulation across germline and somatic variation on the Y chromosome contributes to type 2 diabetes

von FinnGen ; the Japan COVID-19 Task Force ; The Biobank Japan Project ; et al.

Schlagworte: Genetics; developmental biology; physiology; Mosaic loss; Design; Expression; Project; Blood
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6
Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases

von Samantha L White ; Maizy S Brasher ; Jack Pattee ; et al.

Schlagworte: Agricultural biotechnology; Biological sciences; Bioinformatics and computational biology; Genetics; Biomedical and clinical sciences; Genome-wide association studies; Thyroid cancer
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7
Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases

von White, Samantha L. ; Brasher, Maizy S. ; Pattee, Jack ; et al.

PMC

Schlagworte: Genome-wide association studies; Thyroid cancer; Genetic predisposition to disease; Thyroid neoplasms
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8
All‐cause and cardiovascular disease mortality in underweight patients with diabetic nephropathy: BioBank Japan cohort

von Hiroshi Yokomichi ; Mie Mochizuki ; Makoto Hirata ; et al.

Journal of Diabetes Investigation, Vol 12, Iss 8, Pp 1425-1429 (2021)

Schlagworte: Diabetic nephropathy; Mortality; Underweight; Diseases of the endocrine glands. Clinical endocrinology; RC648-665
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9
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

von Puya Gharahkhani ; Eric Jorgenson ; Pirro Hysi ; et al.

Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

Schlagworte: Science
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10
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

von Adams, Mark J. ; Streit, Fabian ; Meng, Xiangrui ; et al.

In Cell 6 February 2025 188(3):640-652
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11
Cause‐specific mortality rates in patients with diabetes according to comorbid macro‐ and microvascular complications: BioBank Japan Cohort

von Hiroshi Yokomichi ; Akiko Nagai ; Makoto Hirata ; et al.

Endocrinology, Diabetes & Metabolism, Vol 4, Iss 1, Pp n/a-n/a (2021)

Schlagworte: cancer; cause of death; diabetic vascular complications; mortality rate; Diseases of the endocrine glands. Clinical endocrinology; RC648-665
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12
Transcriptome- and proteome-wide association studies identify genes associated with renal cell carcinoma

von Purdue, Mark P. ; Dutta, Diptavo ; Machiela, Mitchell J. ; et al.

In The American Journal of Human Genetics 5 September 2024 111(9):1864-1876
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13
Germline variants and mosaic chromosomal alterations affect COVID-19 vaccine immunogenicity

von BioBank Japan Project ; Japan COVID-19 Task Force ; Sonehara, Kyuto ; et al.

Schlagworte: clonal hematopoiesis; COVID-19 vaccine; genome-wide association study; Graves’ disease; immunogenicity; immunoglobulin heavy chain; major histocompatibility complex; mosaic chromosomal alteration; mosaic loss of chromosome X; mosaic loss of chromosome Y; sepsis; Biomedicine; General medicine; internal medicine and other clinical medicine
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14
Understanding the genetic complexity of puberty timing across the allele frequency spectrum

von ABCTB Investigators ; The Lifelines Cohort Study ; The Danish Blood Donor Study ; et al.

Schlagworte: Genetics; developmental biology; physiology
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15
Global multi-ancestry genetic study elucidates genes and biological pathways associated with thyroid cancer and benign thyroid diseases

von White, Samantha L. ; Brasher, Maizy S. ; Pattee, Jack ; et al.

PMC

Schlagworte: Thyroid diseases; Genetic correlation; Genetic predisposition; Thyroid cancer risk
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16
Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases

von Roselli,Carolina ; Surakka,Ida ; Olesen,Morten S ; et al.

Schlagworte: Atrial Fibrillation/genetics; Chromatin/genetics; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Male; Multifactorial Inheritance/genetics; Myocytes; Cardiac/metabolism; Polymorphism; Single Nucleotide; Risk Factors; Taverne; Journal Article; Meta-Analysis
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17
Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population

von Nobuyuki Enzan ; Kazuo Miyazawa ; Satoshi Koyama ; et al.

Nature Communications, Vol 16, Iss 1, Pp 1-16 (2025)

Schlagworte: Science
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18
Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

von Zhou, Wei ; Kanai, Masahiro ; Wu, Kuan-Han H. ; et al.

In Cell Genomics 14 December 2022 2(12)
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19
Large-Scale Blood Pressure Gwas Accounting for Gene-Depression Interactions in 564,680 Individuals From Diverse Populations

von Lee, Songmi ; Miller, Clint L ; Bentley, Amy R ; et al.

Faculty, Staff and Student Publications

Schlagworte: blood pressure; depressive symptomatology; gene-environment interactions; genetics; genome-wide association study; hypertension; multi-ancestry; Medicine and Health Sciences; Public Health
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20
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21
Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference.

von Xiangrui Meng ; Georgina Navoly ; Olga Giannakopoulou ; et al.

Schlagworte: GWAS; major depression; multi ancestry
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22
Understanding the genetic complexity of puberty timing across the allele frequency spectrum.

von Kentistou, K. ; Kaisinger, L. ; Stankovic, S. ; et al.
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23
Understanding the genetic complexity of puberty timing across the allele frequency spectrum

von Katherine A. Kentistou ; Lena R. Kaisinger ; Stasa Stankovic ; et al.

Schlagworte: Puberty timing; Genome-wide Association Study meta-analysi; Exome-wide Association Study
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24
Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference.

von X Meng ; G Navoly ; O Giannakopoulou ; et al.

Schlagworte: Depression; Genome-wide association studies
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25
Susceptibility loci and polygenic architecture highlight population specific and common genetic features in inguinal hernias: genetics in inguinal hernias

von Hikino, Keiko ; Koido, Masaru ; Tomizuka, Kohei ; et al.

In EBioMedicine August 2021 70
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