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von Fountoulakis, Konstantinos N. ; Vrublevska, Jelena ; Abraham, Seri ; et al.
In Journal of Affective Disorders 1 May 2024 352:536-551
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von Fountoulakis, Konstantinos N. ; Karakatsoulis, Grigorios N. ; Abraham, Seri ; et al.
In Psychiatry Research September 2022 315
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von Fountoulakis, Konstantinos N ; Karakatsoulis, Grigorios ; Abraham, Seri ; et al.
In European Neuropsychopharmacology January 2022 54:21-40
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Schlagworte: Ageing; CellPopAge epigenetic Clock; CpG methylation; Drug discovery; Rapamycin; Senescence; Humans; Animals; DNA Methylation; Longevity; Aging; Epigenesis; Genetic; Cellular Senescence; Drug Evaluation; Preclinical; Drosophila; Cells; Cultured; Sirolimus
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von Aman, Yahyah ; Schmauck-Medina, Tomas ; Hansen, Malene ; et al.
Nature Aging. 1(8):634-650
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von Lennicke, C ; Bjedov, I ; Grönke, S ; et al.
Schlagworte: Animals; Drosophila; Drosophila melanogaster; Hydrogen Peroxide; Catalase; Drosophila Proteins; Oxidation-Reduction; Oxidative Stress; Aging; Longevity; Autophagy; Female; Autophagy-Related Proteins; Article
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von Martinez-Miguel, VE ; Lujan, C ; Espie-Caullet, T ; et al.
Cell Metabolism (2021) (In press).
Schlagworte: RPS23; aging; archaea; mTOR; protein synthesis; proteostasis; ribosome; translation; translation accuracy; translation fidelity
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Schlagworte: DNA damage; DNA repair; ageing; cancer; chromatin; epigenetic; healthspan; lifespan; longevity; mutation; stem cells
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von Bjedov, I ; Cochemé, HM ; Foley, A ; et al.
PLOS Genetics , 16 (11) , Article e1009083. (2020)
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von Eleanor R. Stead ; Jorge I. Castillo-Quan ; Victoria Eugenia Martinez Miguel ; et al.
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Schlagworte: autophagy; aging; target of rapamycin; insulin/IGF-1 signaling; proteostasis; DNA damage; Biology (General); QH301-705.5
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von Stead, ER ; Castillo-Quan, JI ; Miguel, VEM ; et al.
Frontiers in Cell and Developmental Biology , 7 , Article 308. (2019)
Schlagworte: autophagy; aging; target of rapamycin; insulin/IGF-1 signaling; proteostasis; DNA damage; mitophagy; anti-aging drugs
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von Castillo-Quan, JI ; Tain, LS ; Kinghorn, KJ ; et al.
Proceedings of the National Academy of Sciences of the United States of America , 116 (42) pp. 20817-20819. (2019)
Schlagworte: aging; lithium; polypharmacology; rapamycin; trametinib
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von Pryor, R ; Norvaisas, P ; Marinos, G ; et al.
Cell , 178 (6) 1299-1312.e29. (2019)
Schlagworte: C. elegans; CRP signaling; Drosophila; aging; diet; humans; metabolic modeling; metformin; microbiome; type-2 diabetes
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von Klionsky, Dj ; Abdelmohsen, K ; Abe, A ; et al.
Schlagworte: LC3; autolysosome; autophagosome; chaperone-mediated autophagy; flux; lysosome; macroautophagy; phagophore; stre; vacuole
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von Klionsky D. J. ; Abdelmohsen K. ; Abe A. ; et al.
Schlagworte: No keywords are available
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von Kerr, F ; Bjedov, I ; Sofola-Adesakin, O
Frontiers in Molecular Neuroscience , 11 , Article 297. (2018)
Schlagworte: lithium; dementia; GSK-3; oxidative damage; neuro-inflammation; proteostasis; neurogenesis; synaptic maintenance
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von Kulaberoglu, Y ; Lin, K ; Holder, M ; et al.
Nature Communications , 8 , Article 695. (2017)
Schlagworte: Science & Technology; Multidisciplinary Sciences; Science & Technology - Other Topics; HUMAN NDR KINASES; TUMOR-SUPPRESSOR; CELL-PROLIFERATION; PROMOTES APOPTOSIS; STRUCTURAL BASIS; PROTEIN-KINASE; PATHWAY; DROSOPHILA; ACTIVATION; FAMILY
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von Kinghorn, KJ ; Groenke, S ; Castillo-Quan, JI ; et al.
JOURNAL OF NEUROSCIENCE , 36 (46) pp. 11654-11670. (2016)
Schlagworte: Science & Technology; Life Sciences & Biomedicine; Neurosciences; Neurosciences & Neurology; autophagy; Drosophila; Gaucher disease; glucocerebrosidase; mTOR; rapamycin; TANDEM MASS-SPECTROMETRY; PARKINSONS-DISEASE; AMINO-ACIDS; MOUSE MODEL; V-ATPASE; LONGEVITY; MELANOGASTER; BIOGENESIS; PROTEINS; MICE
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von Castillo-Quan, JI ; Li, L ; Kinghorn, KJ ; et al.
Cell Reports , 15 (3) pp. 638-650. (2016)
Schlagworte: GSK-3; Keap1; NRF-2; aging; dietary restriction; triglycerides; xenobiotic stress
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von Sofola-Adesakin, O ; Castillo-Quan, JI ; Rallis, C ; et al.
Front Aging Neurosci , 6 , Article 190. (2014)
Schlagworte: Alzheimer's disease; Drosophila; lifespan; lithium; translation
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von Partridge, L ; Alic, N ; Bjedov, I ; et al.
Experimental Gerontology , 46 (5) 376 - 381. (2011)
Schlagworte: Aging; Drosophila; Insulin/Igf signalling; TOR; Dietary restriction; Life-span extension; Stem-cell maintenance; Germ-line; Oxidative stress; Fat-body; Dfoxo; Melanogaster; Mechanisms; Genetics
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von Bjedov, I ; Toivonen, JM ; Kerr, F ; et al.
Cell Metabolism , 11 (1) 35 - 46. (2010)
Schlagworte: s6 kinase; caenorhabditis-elegans; dietary restriction; autophagy genes; c-elegans; insulin-resistance; stress resistance; adult drosophila; cell-survival; growth
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von Toivonen, JM ; Walker, GA ; Martinez-Diaz, P ; et al.
PLoS Genetics , 3 (6) , Article e95. (2007)
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