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1
Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury

von Larraufie, Marie-Hélène ; Gao, Xiaolin ; Xia, Xiaobo ; et al.

In Cell Chemical Biology 16 September 2021 28(9):1271-1282
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2
Systematic Chemogenetic Library Assembly

von Canham, Stephen M. ; Wang, Yuan ; Cornett, Allen ; et al.

In Cell Chemical Biology 17 September 2020 27(9):1124-1129
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3
Discovery of LFF571: An Investigational Agent for Clostridium difficile Infection

von LaMarche, Matthew J. ; Leeds, Jennifer A. ; Amaral, Adam ; et al.

Journal of Medicinal Chemistry. 55(5):2376-2387
- View full text at ACS Publications
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4
Antibacterial Optimization of 4-Aminothiazolyl Analogues of the Natural Product GE2270 A: Identification of the Cycloalkylcarboxylic Acids

von LaMarche, Matthew J. ; Leeds, Jennifer A. ; Amaral, Kerri ; et al.

Journal of Medicinal Chemistry. 54(23):8099-8109
- View full text at ACS Publications
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5
Progress toward a Rationally Designed, Chemically Powered Rotary Molecular Motor

von Kelly, T. Ross ; Cai, Xiaolu ; Damkaci, Fehmi ; et al.

Journal of the American Chemical Society. 129(2):376-386
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6
A Three-Component Coupling Process Based on Vicarious Nucleophilic Substitution (VNSAR)−Alkylation Reactions: An Approach to Indoprofen and Derivatives

von Lawrence, Nicholas J. ; Liddle, John ; Bushell, Simon. M. ; et al.

The Journal of Organic Chemistry. 67(2):457-464
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7
Rapid Evaluation of Small Molecule Cellular Target Engagement with a Luminescent Thermal Shift Assay

von Mortison, Jonathan D. ; Cornella-Taracido, Ivan ; Venkatchalam, Gireedhar ; et al.

ACS Medicinal Chemistry Letters. 12(8):1288-1294
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8
Discovery of a ZIP7 inhibitor from a Notch pathway screen

von Nolin, Erin ; Gans, Sara ; Llamas, Luis ; et al.

Nature Chemical Biology. 15(2):179-188
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9
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation

von Rödström, Karin E. J. ; Cloake, Alexander ; Sörmann, Janina ; et al.

Nature Communications. 15(1)
- Zum Volltext in PubMed Central
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10
The structural basis of fatty acid elongation by the ELOVL elongases

von Nie, Laiyin ; Pascoa, Tomas C. ; Pike, Ashley C. W. ; et al.

Nature Structural & Molecular Biology. 28(6):512-520
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11
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

von Bushell, Simon R. ; Pike, Ashley C. W. ; Falzone, Maria E. ; et al.

Nature Communications. 10(1)
- Zum Volltext in PubMed Central
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12
Costs and complications of extracorporeal membrane oxygenation therapy in Australia and New Zealand

von Wilcox, Kate R. ; Meredith, Lane ; Burrell, Aidan ; et al.

Critical Care. 30(1)
- Zum Volltext in PubMed Central
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13
A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

von Zou, Xueqing ; Koh, Gene Ching Chiek ; Nanda, Arjun Scott ; et al.

Nature Cancer. 2(6):643-657
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14
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

von Najumudeen, Arafath K. ; Ceteci, Fatih ; Fey, Sigrid K. ; et al.

Nature Genetics. 53(1):16-26
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15
Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation

von Carson, Cheryl ; Raman, Pichai ; Tullai, Jennifer ; et al.

PLOS ONE ; volume 10, issue 6, page e0127498 ; ISSN 1932-6203
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16
Total Synthesis of Nigellicine and Nigeglanine Hydrobromide

von Elliott, Eric L. ; Bushell, Simon M. ; Cavero, Marta ; et al.

Organic Letters. 7(12):2449-2451
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17
Enantioselective synthesis of 1-methoxy- and 1-deoxy-2′-methyl-Δ8-tetrahydrocannabinols: New selective ligands for the CB2 receptor

von Huffman, John W. ; Bushell, Simon M. ; Joshi, Sudhir N. ; et al.

In Bioorganic & Medicinal Chemistry 1 January 2006 14(1):247-262
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18
Total Synthesis of Nigellicine and Nigeglanine Hydrobromide.

von Elliot, Eric L. ; Bushell, Simon M. ; Cavero, Marta ; et al.

ChemInform ; volume 36, issue 44 ; ISSN 0931-7597 1522-2667
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19
1-Methoxy-, 1-deoxy-11-hydroxy- and 11-Hydroxy-1-methoxy-Δ 8-tetrahydrocannabinols: new selective ligands for the CB 2 receptor

von Huffman, John W ; Bushell, Simon M ; Miller, John R.A ; et al.

In Bioorganic & Medicinal Chemistry 2002 10(12):4119-4129
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20
Performance of the PEdiatric Logistic Organ Dysfunction-2 score in critically ill children requiring plasma transfusions

von Karam, Oliver ; Demaret, Pierre ; Duhamel, Alain ; et al.

Annals of Intensive Care

Schlagworte: Children; Critical care; Multiple organ failure; Outcome; Plasma transfusion; Score; Contribution to Journal
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21
Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study

von Weiss, Scott L. ; Fitzgerald, JulieC. ; Maffei, Frank ; et al.

Schlagworte: Adolescent; Biomedical Research; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Observer Variation; Practice Patterns, Physicians'; Prevalence; Sepsis; Treatment Outcome; Article
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22
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23
ChemInform Abstract: A Three‐Component Coupling Process Based on Vicarios Nucleophilic Substitution (VNS AR )—Alkylation Reactions: An Approach to Indoprofen and Derivatives.

von Lawrence, Nicholas J. ; Liddle, John ; Bushell, Simon M. ; et al.

ChemInform ; volume 33, issue 26 ; ISSN 0931-7597 1522-2667
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24
ChemInform Abstract: The Asymmetric Synthesis and Stereochemical Assignment of Chelonin B.

von Lawrence, Nicholas J. ; Bushell, Simon M.

ChemInform ; volume 33, issue 4 ; ISSN 0931-7597 1522-2667
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25
ChemInform Abstract: An Efficient Protocol for the Reduction of Ketones with Tin(II) Complexes and PMHS.

von Lawrence, Nicholas J. ; Bushell, Simon M.

ChemInform ; volume 31, issue 35 ; ISSN 0931-7597 1522-2667
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