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1
Polygenic prediction of body mass index and obesity through the life course and across ancestries

von Smit RAJ ; Wade KH ; Hui Q ; et al.

Schlagworte: Polygenic score; body mass index
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2
A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data

von Murrin, O ; Mounier, N ; Voller, B ; et al.
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3
Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity from a common risk factor

von Liang, X ; Mounier, N ; Apfel, N ; et al.
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4
Clinical utility of self-reported sleep duration and insomnia symptoms in type 2 diabetes prediction

von Wright, AK ; Huang, T ; Carr, MJ ; et al.
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5
The role of accelerometer-derived sleep traits on glycated haemoglobin and glucose levels: a Mendelian randomization study

von Liu, J ; Richmond, RC ; Anderson, EL ; et al.
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6
Loci for insulin processing and secretion provide insight into type 2 diabetes risk

von Broadaway, KA ; Yin, X ; Williamson, A ; et al.
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7
Identification and analysis of individuals who deviate from their genetically-predicted phenotype.

von Hawkes, G ; Yengo, L ; Vedantam, S ; et al.

Schlagworte: Humans; Child; Genome-Wide Association Study; Cholesterol; LDL; Phenotype; Coronary Artery Disease; Follow-Up Studies; Mendelian Randomization Analysis; Risk Factors; Polymorphism; Single Nucleotide
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8
A Saturated Map of Common Genetic Variants Associated with Human Height

von Yengo, Loïc ; Vedantam, Sailaja ; Miao, Jenkai ; et al.

Schlagworte: common single-nucleotide polymorphisms (SNPs); human height; genome; ancestry
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9
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

von Kanoni, Stavroula ; Graham, Sarah E. ; Locke, Adam E. ; et al.

Schlagworte: cholesterol; lipids; genetics; genome-wide association study (GWAS); SDG 3; Sustainable Development Goals
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10
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.

von Kanoni, S ; Graham, SE ; Wang, Y ; et al.
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11
A saturated map of common genetic variants associated with human height.

von Yengo, L ; Vedantam, S ; Marouli, E ; et al.
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12
Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation.

von Martin, S ; Tyrrell, J ; Thomas, EL ; et al.

Schlagworte: Mendelian randomisation; cancer; cardiovascular disease; epidemiology; favourable adiposity; genetics; genomics; global health; human; obesity; Adiposity; Adult; Aged; 80 and over; Body Mass Index; Cardiometabolic Risk Factors; Female; Genome-Wide Association Study; Humans; Male; Mendelian Randomization Analysis; Middle Aged
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13
Genetic insights into biological mechanisms governing human ovarian ageing

von Ruth KS ; Day FR ; Hussain J ; et al.

Schlagworte: Settore MED/01 - Statistica Medica
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14
The trans-ancestral genomic architecture of glycemic traits

von Chen, J ; Spracklen, CN ; Marenne, G ; et al.

Nature Genetics , 53 (6) pp. 840-860. (2021)

Schlagworte: WIDE ASSOCIATION; INSULIN-RESISTANCE; GENE-EXPRESSION; DISEASE RISK; VARIANTS; GLUCOSE; LOCI; METAANALYSIS; MECHANISMS; HEMOGLOBIN
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15
Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity

von Deshmukh HA ; Madsen AL ; Vinuela A ; et al.

The Journal of Clinical Endocrinology & Metabolism, 1 January 2021
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16
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

von Romagnoni, A ; Jegou, S ; VAN STEEN, Kristel ; et al.
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17
Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

von Lagou, V ; Mägi, R ; Hottenga, J-J ; et al.

Nature Communications , 12 , Article 995. (2021)

Schlagworte: Diagnostic markers; Genome-wide association studies; Pre-diabetes; Quantitative trait; Type 2 diabetes
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18
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

von Lagou, V ; Mägi, R ; Hottenga, J-J ; et al.

Nature Communications , 12 , Article 24. (2021)
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19
Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile

von Heald, AH ; Martin, S ; Fachim, H ; et al.
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20
Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile

von Thompson, WD ; Beaumont, RN ; Kuang, A ; et al.

Schlagworte: adiposity; ALSPAC; BiB; BMI; EFSOCH; glucose; HAPO; insulin; Mendelian randomisation; UKB
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21
Machine learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits.

von Glastonbury, CA ; Pulit, SL ; Honecker, J ; et al.
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22
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

von Erzurumluoglu, AM ; Liu, M ; Jackson, VE ; et al.
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23
The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

von Middeldorp, CM ; Mahajan, A ; Horikoshi, M ; et al.
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24
Exome-derived adiponectin-associated variants implicate obesity and lipid biology

von Spracklen, CN ; Karaderi, T ; Yaghootkar, H ; et al.
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25
Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

von Dashti, HS ; Jones, SE ; Wood, AR ; et al.

Dashti, HS, Jones, SE, Wood, AR, Lane, JM, van Hees, VT, Wang, HM, Rhodes, JA, Song, YW, Patel, KN, Anderson, SG, Beaumont, RN, Bechtold, DA, Bowden, J, Cade, BE, Garaulet, M, Kyle, SD, Little, M A, Loudon, AS, Luik, AI, Scheer, F, Spiegelhalder, K, Tyrrell, J, Gottlieb, DJ, Tiemeier, H, Ray, DW, Purcell, SM, Frayling, TM, Redline, S, Lawlor, DA, Rutter, MK, Weedon, MN & Saxena, R 2019, 'Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates', Nature Communications, vol. 10, 1100. https://doi.org/10.1038/s41467-019-08917-4

Schlagworte: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCNIHES016401; name=EMC NIHES-01-64-01
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