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1
Dissecting myocardial and systemic drivers of cardiac dysfunction in the murine CVB3 myocarditis model using microRNA-guided viral detargeting

von Ochs, Sarah ; Pinkert, Sandra ; Borowski, Sophia ; et al.

Basic Research in Cardiology. 121(4):775-799
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2
Arming Oncolytic Coxsackievirus B3 with Neoleukin-2/15 enhances growth inhibition of colorectal carcinomas and induces T-cell activation

von Elsner, Leslie ; Girod, Maxim ; Hazini, Ahmet ; et al.

In Molecular Therapy: Oncology July 2026
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3
Improved Safety of New MicroRNA-Regulated Oncolytic Coxsackievirus B3 Observed After Intravenous Administration in Colorectal-Tumor-Bearing Mice

von Elsner, Leslie ; Hinze, Luisa ; Hazini, Ahmet ; et al.

Schlagworte: oncolytic virus; coxsackievirus B3; cancer; colorectal carcinoma; microRNAs; PD-H; intravenous application; ddc:570
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4
Cancer-Related Immune Therapies: Bidirectional Implications From Cardiotoxicity to Emerging Cardiovascular Therapeutics: JACC CardioOncology State-of-the-Art Review

von Miteva, Kapka ; Anker, Markus S. ; Fechner, Henry ; et al.

In JACC: CardioOncology August 2025 7(5):523-537
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5
Improved Safety of New MicroRNA-Regulated Oncolytic Coxsackievirus B3 Observed After Intravenous Administration in Colorectal-Tumor-Bearing Mice

von Leslie Elsner ; Luisa Hinze ; Ahmet Hazini ; et al.

Viruses, Vol 18, Iss 1, p 143 (2026)

Schlagworte: oncolytic virus; coxsackievirus B3; cancer; colorectal carcinoma; microRNAs; PD-H; Microbiology; QR1-502
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6
Fast Track Adaptation of Oncolytic Coxsackie B3 Virus to Resistant Colorectal Cancer Cells - a Method to Personalize Virotherapy

von Elsner, Leslie ; Heimann, Lisanne ; Geisler, Anja ; et al.

Biological Procedures Online. 26(1)
- Zum Volltext in PubMed Central
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7
Fast Track Adaptation of Oncolytic Coxsackie B3 Virus to Resistant Colorectal Cancer Cells - a Method to Personalize Virotherapy

von Elsner, Leslie ; Heimann, Lisanne ; Geisler, Anja ; et al.

Schlagworte: 600 Technik; Medizin; angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit; cancer therapy; oncolytic virus; personalized therapy; colorectal carcinoma; direct virus evolution; Coxsackievirus B3
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8
Mitigating murine acute and chronic Coxsackievirus B3-induced myocarditis with human right atrial appendage-derived stromal cells

von El-Shafeey, Muhammad ; Pappritz, Kathleen ; Voss, Isabel ; et al.

Stem Cells Translational Medicine ; volume 14, issue 4 ; ISSN 2157-6564 2157-6580
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9
Lipid nanoparticle-encapsulated, chemically modified anti-adenoviral siRNAs inhibit hepatic adenovirus infection in immunosuppressed Syrian hamsters

von Geisler, Anja ; Dieringer, Babette ; Elsner, Leslie ; et al.

In Molecular Therapy - Nucleic Acids 13 June 2023 32:923-936
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10
Infection of iPSC Lines with Miscarriage-Associated Coxsackievirus and Measles Virus and Teratogenic Rubella Virus as a Model for Viral Impairment of Early Human Embryogenesis

von Hübner, Denise ; Jahn, Kristin ; Pinkert, Sandra ; et al.

ACS Infectious Diseases. 3(12):886-897
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11
Optimized Directed Virus Evolution to Accelerate the Generation of Oncolytic Coxsackievirus B3 Adapted to Resistant Colorectal Cancer Cells

von Leslie Elsner ; Babette Dieringer ; Anja Geisler ; et al.

Viruses, Vol 16, Iss 12, p 1958 (2024)

Schlagworte: Coxsackievirus B3; PD-H; oncolytic virus; directed viral evolution; colorectal carcinoma; Microbiology; QR1-502
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12
Combination of FOLFOXIRI Drugs with Oncolytic Coxsackie B3 Virus PD-H Synergistically Induces Oncolysis in the Refractory Colorectal Cancer Cell Line Colo320

von Girod, Maxim ; Geisler, Anja ; Hinze, Luisa ; et al.

Girod, Maxim, Geisler, Anja, Hinze, Luisa, Elsner, Leslie, Dieringer, Babette, Beling, Antje, Kurreck, Jens, Fechner, Henry: Combination of FOLFOXIRI Drugs with Oncolytic Coxsackie B3 Virus PD-H Synergistically Induces Oncolysis in the Refractory Colorectal Cancer Cell Line Colo320, Berlin: Technische Universität Berlin 2024.

Schlagworte: Medizin
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13
Oncolytic Coxsackievirus B3 Strain PD-H Is Effective Against a Broad Spectrum of Pancreatic Cancer Cell Lines and Induces a Growth Delay in Pancreatic KPC Cell Tumors In Vivo

von Geisler, Anja ; Dieringer, Babette ; Elsner, Leslie ; et al.

Geisler, Anja, Dieringer, Babette, Elsner, Leslie, Klopfleisch, Robert, Kurreck, Jens, Fechner, Henry: Oncolytic Coxsackievirus B3 Strain PD-H Is Effective Against a Broad Spectrum of Pancreatic Cancer Cell Lines and Induces a Growth Delay in Pancreatic KPC Cell Tumors In Vivo, Berlin: Technische Universität Berlin 2024.

Schlagworte: Medizin
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14
Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis

von Kathleen Pappritz ; Jie Lin ; Muhammad El‐Shafeey ; et al.

ESC Heart Failure, Vol 9, Iss 2, Pp 925-941 (2022)

Schlagworte: Coxsackievirus B3; Myocarditis; Colchicine; Cardiosplenic axis; Inflammation; Diseases of the circulatory (Cardiovascular) system; RC666-701
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15
Silencing of Mcl-1 overcomes resistance of melanoma cells against TRAIL-armed oncolytic adenovirus by enhancement of apoptosis

von Tolksdorf, Beatrice ; Zarif, Sina ; Eberle, Jürgen ; et al.

Journal of Molecular Medicine. 99(9):1279-1291
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16
Variability in Cardiac miRNA-122 Level Determines Therapeutic Potential of miRNA-Regulated AAV Vectors

von Kraszewska, Izabela ; Tomczyk, Mateusz ; Andrysiak, Kalina ; et al.

In Molecular Therapy - Methods & Clinical Development 12 June 2020 17:1190-1201
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17
RNA interference-mediated silencing of Kv7.2 in rat dorsal root ganglion neurons abolishes the anti-nociceptive effect of a selective channel opener

von Valdor, Markus ; Wagner, Anke ; Fischer, Heike ; et al.

In Journal of Pharmacological and Toxicological Methods May-June 2020 103
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18
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19
Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis

von Pappritz, Kathleen ; Lin, Jie ; El‐Shafeey, Muhammad ; et al.

Schlagworte: Coxsackievirus B3; Myocarditis; Colchicine; Cardiosplenic axis; Inflammation; ddc:610
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20
Anti-adenoviral Artificial MicroRNAs Expressed from AAV9 Vectors Inhibit Human Adenovirus Infection in Immunosuppressed Syrian Hamsters

von Schaar, Katrin ; Geisler, Anja ; Kraus, Milena ; et al.

In Molecular Therapy - Nucleic Acids 15 September 2017 8:300-316
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21
Virotherapy in Germany—Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies

von Nettelbeck, Dirk M. ; Leber, Mathias Felix ; Altomonte, Jennifer ; et al.

Viruses, 13(8):1420

Schlagworte: immunotherapy; therapeutic transgene; combination therapy; Virustherapie; clinical trials; virus engineering; oncolytic virus; research in Germany; virus targeting; virotherapy
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22
Soluble coxsackie- and adenovirus receptor (sCAR-Fc); a highly efficient compound against laboratory and clinical strains of coxsackie-B-virus

von Pinkert, Sandra ; Dieringer, Babette ; Diedrich, Sabine ; et al.

In Antiviral Research December 2016 136:1-8
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23
Coxsackievirus B3—Its Potential as an Oncolytic Virus

von Geisler, Anja ; Hazini, Ahmet ; Heimann, Lisanne ; et al.

Schlagworte: 610 Medizin und Gesundheit; Coxsackievirus B3; microRNA; miR; oncolytic virus; cancer; virus adaptation
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24
Application Route and Immune Status of the Host Determine Safety and Oncolytic Activity of Oncolytic Coxsackievirus B3 Variant PD-H

von Hazini, Ahmet ; Dieringer, Babette ; Klingel, Karin ; et al.

Schlagworte: 610 Medizin und Gesundheit; coxsackievirus B3; oncolytic virus; cancer; colorectal carcinoma; microRNAs; PD
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25
Application Route and Immune Status of the Host Determine Safety and Oncolytic Activity of Oncolytic Coxsackievirus B3 Variant PD-H

von Ahmet Hazini ; Babette Dieringer ; Karin Klingel ; et al.

Viruses, Vol 13, Iss 10, p 1918 (2021)

Schlagworte: coxsackievirus B3; oncolytic virus; cancer; colorectal carcinoma; microRNAs; PD; Microbiology; QR1-502
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