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1
Characteristics and safety outcomes of rheumatoid arthritis patients treated with AMGEVITA® in the United Kingdom using data from a national register

von Argentina E. Servin ; Mark Lillie ; Ran Jin ; et al.

Arthritis Research & Therapy, Vol 28, Iss 1 (2026)

Schlagworte: Rheumatoid arthritis; Biosimilars; Biologics; BSRBR-RA; Diseases of the musculoskeletal system; RC925-935
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2
Fibroblast–Neuron interactions Driving persistent Pain in Rheumatoid Arthritis (FiND-Pain RA) – an observational study protocol

von Frances Humby ; Christopher D Buckley ; David L Bennett ; et al.

BMJ Open, Vol 15, Iss 12 (2025)

Schlagworte: Medicine
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3
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis

von Alessandra Nerviani ; Marie-Astrid Boutet ; Giulia Maria Ghirardi ; et al.

Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Schlagworte: Science
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4
Editorial: Synovial pathobiology and pathogenesis of inflammatory arthritis, volume II

von Annabelle Small ; Frances Humby ; Mihir D. Wechalekar

Frontiers in Medicine, Vol 11 (2024)

Schlagworte: synovium; rheumatoid arthritis; psoriatic arthritis; post-traumatic knee osteoarthritis; pathogenesis; precision medicine; Medicine (General); R5-920
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5
Review: Remote disease monitoring in rheumatoid arthritis

von Amy MacBrayne ; William Marsh ; Frances Humby

Indian Journal of Rheumatology, Vol 17, Iss 7, Pp 384-393 (2022)

Schlagworte: application; mhealth; remote monitoring; rheumatoid arthritis; smartphone; Diseases of the musculoskeletal system; RC925-935
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6
Editorial: Synovial pathobiology and pathogenesis of inflammatory arthritis

von Annabelle Small ; Frances Humby ; Mihir D. Wechalekar

Frontiers in Medicine, Vol 9 (2022)

Schlagworte: synovium; rheumatoid arthritis; pathogenesis; inflammatory arthritis; precision medicine; Medicine (General); R5-920
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7
Rituximab versus tocilizumab and B-cell status in TNF-alpha inadequate-responder rheumatoid arthritis patients: the R4-RA RCT

von Frances Humby ; Patrick Durez ; Maya H Buch ; et al.

Efficacy and Mechanism Evaluation, Vol 9, Iss 7 (2022)

Schlagworte: rheumatoid arthritis; biologic; synovium; synovial tissue; histology; ultrasound; rituximab; tocilizumab; Medicine
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8
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis

von Lewis, Myles J. ; Çubuk, Cankut ; Surace, Anna E. A. ; et al.

Nature Communications. 16(1)
- Zum Volltext in PubMed Central
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9
Editorial: Synovial Tissue: Turning the Page to Precision Medicine in Arthritis?

von Carl Kieran Orr ; Frances Humby ; João Eurico Fonseca

Frontiers in Medicine, Vol 8 (2021)

Schlagworte: synovial biopsy; synovial tissue; synovial tissue analysis; synovial membrane; inflammation; arthritis; Medicine (General); R5-920
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10
Standardisation of synovial biopsy analyses in rheumatic diseases: a consensus of the EULAR Synovitis and OMERACT Synovial Tissue Biopsy Groups

von Aurélie Najm ; Benoît Le Goff ; Carl Orr ; et al.

Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-7 (2018)

Schlagworte: Synovium; Standardisation; Synovial biopsy; Synovial tissue analysis; Diseases of the musculoskeletal system; RC925-935
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11
Fibrocytes in early and long-standing rheumatoid arthritis: a 6-month trial with repeated synovial biopsy, imaging and lung function test

von Søren Andreas Just ; Frances Humby ; Hanne Lindegaard ; et al.

RMD Open, Vol 7, Iss 1 (2021)

Schlagworte: Medicine
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12
Causal Bayesian Networks for Medical Diagnosis: A Case Study in Rheumatoid Arthritis

von Fahmi, Ali ; MacBrayne, Amy ; Kyrimi, Evangelia ; et al.

2020 IEEE International Conference on Healthcare Informatics (ICHI) Healthcare Informatics (ICHI), 2020 IEEE International Conference on. :1-7 Nov, 2020
- Zum Volltext in IEEE Xplore
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13
Ultrasound-Guided Synovial Biopsy Can Be Effectively and Safely Performed in Different Clinical Settings Favouring a Widespread Application of Precision Medicine in Rheumatoid Arthritis: A Post-hoc Analysis of Three Clinical Trials

von Mattia Congia ; Stefano Marini ; Alessandra Nerviani ; et al.

Journal of Clinical Medicine ; Volume 15 ; Issue 6 ; Pages: 2233

Schlagworte: rheumatoid arthritis; synovial biopsy; precision medicine
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14
Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus

von Suzanne Cole ; Alice Walsh ; Xuefeng Yin ; et al.

Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-14 (2018)

Schlagworte: CD38; Plasma cell; Daratumumab; Rheumatoid arthritis; Systemic lupus erythematosus; Diseases of the musculoskeletal system; RC925-935
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15
A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients

von Alessandra Nerviani ; Maria Di Cicco ; Arti Mahto ; et al.

Frontiers in Immunology, Vol 11 (2020)

Schlagworte: synovial tissue; anti-TNF; pathotype; rheumatoid arthritis; certolizumab-pegol; Immunologic diseases. Allergy; RC581-607
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16
Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

von Myles J. Lewis ; Michael R. Barnes ; Kevin Blighe ; et al.

Cell Reports, Vol 28, Iss 9, Pp 2455-2470.e5 (2019)

Schlagworte: Biology (General); QH301-705.5
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17
Dynamic Bayesian network models for self-management of chronic diseases: Rheumatoid arthritis case-study

von Fahmi, Ali ; MacBrayne, Amy ; Humby, Frances ; et al.

In Computers in Biology and Medicine May 2025 189
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18
Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.

von Yanxia Guo ; Alice M Walsh ; Mary Canavan ; et al.

PLoS ONE, Vol 13, Iss 2, p e0192704 (2018)

Schlagworte: Medicine; Science
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19
Correction to: Standardisation of synovial biopsy analyses in rheumatic diseases: a consensus of the EULAR Synovitis and OMERACT Synovial Tissue Biopsy Groups

von Aurélie Najm ; Benoît Le Goff ; Carl Orr ; et al.

Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-1 (2018)

Schlagworte: Diseases of the musculoskeletal system; RC925-935
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20
Stratification of biological therapies by pathobiology in biologic-naive patients with rheumatoid arthritis (STRAP and STRAP-EU): two parallel, open-label, biopsy-driven, randomised trials

von Zayat, Ahmed ; Machado, Ana Rita ; Cuervo, Andrea ; et al.

In The Lancet Rheumatology November 2023 5(11):e648-e659
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21
Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium.

von Frances Humby ; Michele Bombardieri ; Antonio Manzo ; et al.

PLoS Medicine, Vol 6, Iss 1, p e1 (2009)

Schlagworte: Medicine
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22
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial

von Rivellese, Felice ; Surace, Anna E. A. ; Goldmann, Katriona ; et al.

Nature Medicine. 28(6):1256-1268
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23
BiTE therapy for rheumatoid arthritis

von Humby, Frances ; Kirkham, Bruce ; Taams, Leonie

Nature Medicine. 30(6):1533-1534
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24
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25
Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial

von Thompson, Charlotte ; Bugatti, Serena ; Bellan, Mattia ; et al.

In The Lancet 23-29 January 2021 397(10271):305-317
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