Volltext-Artikel, E-Books und Literaturhinweise aus dem EBSCO Discovery Service
"Artikel & mehr" berücksichtigt nur einen Teil der für die Bibliothek der Frankfurt UAS verfügbaren Datenbanken. Zur Übersicht in DBIS
Ergebnis verändern
- Publikationstyp
Publikationstyp- erschienen in
- Verlag
- Geographic terms
- Sprache
- 1
-
2
von Francesca Minnai ; Filippo Biscarini ; Martina Esposito ; et al.
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Schlagworte: Medicine; Science
-
3
von Laura Bergantini ; Margherita Baldassarri ; Miriana d’Alessandro ; et al.
Respiratory Research, Vol 24, Iss 1, Pp 1-9 (2023)
Schlagworte: COVID-19; Pulmonary fibrosis; RTEL1; Long COVID; Diseases of the respiratory system; RC705-779
-
4
von Zguro, Kristina ; Baldassarri, Margherita ; Fava, Francesca ; et al.
Schlagworte: ADAMTS13; COVID-19; add-on therapy; thromboembolism
-
5
von Gabriele Martelloni ; Alessio Turchi ; Chiara Fallerini ; et al.
Frontiers in Genetics, Vol 15 (2024)
Schlagworte: COVID-19; host genetics; integrated polygenic score; genetic algorithm; logistic regression; genetic science modeling; Genetics; QH426-470
-
6
von Anthony Onoja ; Nicola Picchiotti ; Chiara Fallerini ; et al.
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Schlagworte: Biology (General); QH301-705.5
-
7
von Guillaume Butler-Laporte ; Gundula Povysil ; Jack A. Kosmicki ; et al.
Schlagworte: Host genetics is a key determinant of COVID-19 outcomes. Previously; the COVID-19 Host Genetics Initiative genome-wide association study used common variants to identify multiple loci associated with COVID-19 outcomes. However; variants with the largest impact on COVID-19 outcomes are expected to be rare in the population. Hence; studying rare variants may provide additional insights into disease susceptibility and pathogenesis; thereby informing therapeutics development. Here; we combined whole-exome and whole-genome sequencing from 21 cohorts across 12 countries and performed rare variant exome-wide burden analyses for COVID-19 outcomes. In an analysis of 5,085 severe disease cases and 571,737 controls; we observed that carrying a rare deleterious variant in the SARS-CoV-2 sensor toll-like receptor TLR7 (on chromosome X) was associated with a 5.3-fold increase in severe disease (95% CI: 2.75-10.05; p = 5.41x10-7). This association was consistent across sexes. These results further support TLR7 as a genetic determinant of severe disease and suggest that larger studies on rare variants influencing COVID-19 outcomes could provide additional insights
-
8
von Chiara Fallerini ; Sergio Daga ; Elisa Benetti ; et al.
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-4 (2021)
Schlagworte: COVID-19; Thromboembolism; Thrombus; Venous thromboembolism; P-selectin; Anti-selectin P monoclonal antibodies; Diseases of the blood and blood-forming organs; RC633-647.5; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
-
9
von Baldassarri, Margherita ; Zguro, Kristina ; Tomati, Valeria ; et al.
Schlagworte: CFTR complex allele; COVID-19; post-Mendelian model
-
10
von Chiara Fallerini ; Nicola Picchiotti ; Margherita Baldassarri ; et al.
Schlagworte: Adult; Aged; 80 and over; Cohort Studie; COVID-19; Female; Genetic Predisposition to Disease; Germany; Human; Italy; Male; Middle Aged; Phenotype; Polymorphism; Single Nucleotide; Quebec; SARS-CoV-2; Severity of Illness Index; Sweden; United Kingdom; Whole Exome Sequencing
-
11
von Croci, Susanna ; Venneri, Mary Anna ; Mantovani, Stefania ; et al.
Schlagworte: Autophagy; COVID-19; HLA; L412F; TLR3; Biomarker; HEK293 Cell; Human; Hydroxychloroquine; Male; Polymorphism; Single Nucleotide; SARS-CoV-2; Severity of Illness Index; Toll-Like Receptor 3
-
12
von Zanella I. ; Zacchi E. ; Piva S. ; et al.
Schlagworte: Autophagy; C9orf72; COVID-19; Genetic risk; Innate immunity; Intermediate allele; SARS-CoV-2
-
13
von Chiara Fallerini ; Sergio Daga ; Elisa Benetti ; et al.
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-1 (2023)
Schlagworte: Diseases of the blood and blood-forming organs; RC633-647.5; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
-
14
von Butler-Laporte, Guillaume ; Povysil, Gundula ; Kosmicki, Jack A ; et al.
essn: 1553-7404 ; nlmid: 101239074
Schlagworte: Humans; Exome; Genome-Wide Association Study; COVID-19; Genetic Predisposition to Disease; Toll-Like Receptor 7; SARS-CoV-2
- 15
-
16
von Chiara Fallerini ; Sergio Daga ; Stefania Mantovani ; et al.
eLife, Vol 10 (2021)
Schlagworte: TLR7; COVID-19; LASSO Logistic Regression Analysis; Medicine; Science; Biology (General); QH301-705.5
-
17
von Fallerini, Chiara ; Picchiotti, Nicola ; Baldassarri, Margherita ; et al.
Schlagworte: Adult; Aged; 80 and over; COVID-19; Cohort Studies; Female; Genetic Predisposition to Disease; Germany; Humans; Italy; Male; Middle Aged; Phenotype; Polymorphism; Single Nucleotide; Quebec; SARS-CoV-2; Severity of Illness Index; Sweden; United Kingdom; Exome Sequencing
-
18
von Benetti E ; Giliberti A ; Emiliozzi A ; et al.
Schlagworte: COVID-19; Whole exome sequencing
-
19
Schlagworte: COVID-19 (Malaltia); Homes -- Malalties
-
20
von Elisa Benetti ; Annarita Giliberti ; Arianna Emiliozzi ; et al.
PLoS ONE, Vol 15, Iss 11 (2020)
Schlagworte: Medicine; Science
-
21
von Maria Monticelli ; Bruno Hay Mele ; Elisa Benetti ; et al.
Genes ; Volume 12 ; Issue 4 ; Pages: 596
Schlagworte: COVID-19; TMPRSS2; V197M; missense mutation; Whole-Exome Sequencing (WES)
-
22
von Margherita Baldassarri ; Francesca Fava ; Chiara Fallerini ; et al.
Journal of Personalized Medicine, Vol 11, Iss 558, p 558 (2021)
Schlagworte: CF carrier screening; host genetics; COVID-19; CFTR; Medicine
-
23
von Gabriele Martelloni ; Alessio Turchi ; Chiara Fallerini ; et al.
Schlagworte: Genetics; Genetic Engineering; Biomarkers; Developmental Genetics (incl. Sex Determination); Epigenetics (incl. Genome Methylation and Epigenomics); Gene Expression (incl. Microarray and other genome-wide approaches); Genome Structure and Regulation; Genomics; Genetically Modified Animals; Livestock Cloning; Gene and Molecular Therapy; COVID-19; host genetics; integrated polygenic score; genetic algorithm; logistic regression; genetic science modeling
-
24
von Gabriele Martelloni ; Alessio Turchi ; Chiara Fallerini ; et al.
Schlagworte: Genetics; Genetic Engineering; Biomarkers; Developmental Genetics (incl. Sex Determination); Epigenetics (incl. Genome Methylation and Epigenomics); Gene Expression (incl. Microarray and other genome-wide approaches); Genome Structure and Regulation; Genomics; Genetically Modified Animals; Livestock Cloning; Gene and Molecular Therapy; COVID-19; host genetics; integrated polygenic score; genetic algorithm; logistic regression; genetic science modeling
-
25
Dieses Ergebnis aus Science Citation Index Expanded kann Gästen nicht angezeigt werden.
Login für vollen Zugriff.
Hilfe & Kontakt ǀ Fernleihe | Hilfe zur Fernleihe ǀ Literaturvorschlag| Literaturvorschlag