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von Garcia-Martinez, V ; Franco, D ; Garcia-Lopez, V ; et al.
Schlagworte: Saturday 9 July 2016
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von Gowran, A ; Vigorelli, V ; Nigro, P ; et al.
Schlagworte: Sunday 10 July 2016
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von Vajen, T ; Vasina, EM ; Heemskerk, JWM ; et al.
Schlagworte: Saturday 9 July 2016
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von Compeer, MG ; Meens, MJPMT ; Hackeng, TM ; et al.
British Journal of Pharmacology ; volume 166, issue 6, page 1833-1845 ; ISSN 0007-1188 1476-5381
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von Lempens, EHM Edith ; Baal, I Ingrid van ; Dongen, JLJ Joost van ; et al.
ISSN:0947-6539.
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von Hackeng, TM ; Sere, KM ; Tans, G ; et al.
Hackeng, TM, Sere, KM, Tans, G & Rosing, J 2006, 'Protein S stimulates inhibition of the tissue factor pathway by tissue factor pathway inhibitor', Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 9, pp. 3106-3111. https://doi.org/10.1073/pnas.0504240103
Schlagworte: anticoagulant; venous thrombosis; extrinsic coagulation; FACTOR CYTOPLASMIC DOMAIN; FACTOR-XA; FACTOR VIIA; ANTICOAGULANT ACTIVITY; THROMBIN GENERATION; BLOOD-COAGULATION; SLOW-BINDING; FACTOR VA; MODEL; ACTIVATION
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von Denis, CV ; Roberts, SJ ; Hackeng, TM ; et al.
Denis, CV, Roberts, SJ, Hackeng, TM & Lenting, PJ 2005, 'In vivo clearance of human protein S in a mouse model - Influence of c4b-binding protein and the Heerlen polymorphism', Arteriosclerosis Thrombosis and Vascular Biology, vol. 25, no. 10, pp. 2209-2215. https://doi.org/10.1161/01.ATV.0000181760.55269.6b
Schlagworte: protein S; C4b-binding; clearance; FACTOR-VA; ENDOTHELIAL-CELLS; COFACTOR ACTIVITY; APOPTOTIC CELLS; APC-COFACTOR; FACTOR-VIII; SER 460; DEFICIENCY; BINDING; INACTIVATION
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von Heeb, MJ ; Koenen, RR ; Fernandez, JA ; et al.
Heeb, MJ, Koenen, RR, Fernandez, JA & Hackeng, TM 2004, 'Direct anticoagulant activity of protein S-C4b binding protein complex in Heerlen heterozygotes and normals', Journal of Thrombosis and Haemostasis, vol. 2, no. 10, pp. 1766-1773. https://doi.org/10.1111/j.1538-7836.2004.00901.x
Schlagworte: anticoagulant; C4b-binding protein; factor Xa; protein S; S DEFICIENCY; FACTOR-VA; COFACTOR ACTIVITY; RISK-FACTORS; FACTOR-VIII; FACTOR-XA; SER 460; PROTHROMBINASE; PLASMA
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von Hackeng, TM ; Yegneswaran, S ; Johnson, AE ; et al.
Hackeng, TM, Yegneswaran, S, Johnson, AE & Griffin, JH 2000, 'Conformational changes in activated protein C caused by binding of the first epidermal growth factor-like module of protein S', Biochemical Journal, vol. 349, pp. 757-764. https://doi.org/10.1042/bj3490757
Schlagworte: anticoagulant; chemical protein synthesis; fluorescence resonance energy transfer; RESONANCE ENERGY-TRANSFER; PEPTIDE-BOND CLEAVAGES; HUMAN FACTOR-VA; C4B-BINDING PROTEIN; COFACTOR ACTIVITY; FACTOR-XA; PROTHROMBINASE COMPLEX; BETA-HYDROXYASPARAGINE; ENDOTHELIAL-CELLS; FACTOR VA(R506Q)
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von Hackeng, TM ; Fernandez, JA ; Dawson, PE ; et al.
Hackeng, TM, Fernandez, JA, Dawson, PE, Kent, SBH & Griffin, JH 2000, 'Chemical synthesis and spontaneous folding of a multidomain protein : Anticoagulant microprotein S', Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 26, pp. 14074-14078. https://doi.org/10.1073/pnas.260239797
Schlagworte: PHASE PEPTIDE-SYNTHESIS; C4B-BINDING PROTEIN; THROMBOTIC DISEASE; PURPURA FULMINANS; C DEFICIENCY; FACTOR-IX; BINDING; PLASMA; DOMAIN; PURIFICATION
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von Hackeng, TM ; Griffin, JH ; Dawson, PE
Hackeng, TM, Griffin, JH & Dawson, PE 1999, 'Protein synthesis by native chemical ligation : Expanded scope by using straightforward methodology', Proceedings of the National Academy of Sciences of the United States of America, vol. 96, no. 18, pp. 10068-10073. https://doi.org/10.1073/pnas.96.18.10068
Schlagworte: SECRETORY PHOSPHOLIPASE A(2); PHASE PEPTIDE-SYNTHESIS; UNPROTECTED PEPTIDES; GENERAL-METHOD; MODULATION; MECHANISM; COMPLEX
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von Sere, KM ; Willems, GM ; Rosing, J ; et al.
Sere, KM, Willems, GM, Rosing, J & Hackeng, TM 2006, 'Protein S multimers are generated in vitro and affect protein S structure-function analyses', Paper presented at 20th Congress of the International-Society-on-Thrombosis-and-Haemostasis, Sydney, Australia, 6/08/05 - 12/08/05 pp. S111-S120. https://doi.org/10.1053/j.seminhematol.2005.11.027
Schlagworte: HIGH-AFFINITY INTERACTION; HUMAN FACTOR-VIII; C4B-BINDING PROTEIN; FACTOR-VA; COFACTOR ACTIVITY; PROTHROMBINASE COMPLEX; ENDOTHELIAL-CELLS; FACTOR-XA; BINDING; INHIBITION
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von Schmitt, MM ; Megens, RT ; Zernecke, A ; et al.
Schlagworte: info:eu-repo/classification/ddc
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von Koenen, RR ; Hundelshausen, P ; Nesmelova, IV ; et al.
Koenen, RR, Hundelshausen, P, Nesmelova, IV, Zernecke, A, Liehn, EA, Sarabi, A, Kramp, BK, Piccinini, AM, Paludan, S R, Kowalska, MA, Kungl, A, Hackeng, TM, Mayo, KH & Weber, C 2009, 'Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice', Nature Medicine, vol. 15, pp. 97-103.
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