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Treffer 1 - 25 von 3083, Suchdauer: 0.91s

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1
Development of a Dual Chemical Probe for the USP16 and HDAC6 Zinc-Finger Ubiquitin-Binding Domain

von Silva, Madhushika ; Mann, Mandeep ; Mirabi, Bijan ; et al.

Journal of Medicinal Chemistry. 69(5):5703-5711
- View full text at ACS Publications
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2
CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV‑2

von Herasymenko, Oleksandra ; Silva, Madhushika ; Correy, Galen J. ; et al.

Journal of Chemical Information and Modeling. 66(3):1566-1581
- View full text at ACS Publications
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3
Enabling Open Machine Learning of Deoxyribonucleic Acid-Encoded Library Selections to Accelerate the Discovery of Small Molecule Protein Binders

von Wellnitz, James ; Ahmad, Shabbir ; Bagale, Nabin ; et al.

Journal of Medicinal Chemistry. 68(20):21635-21648
- View full text at ACS Publications
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4
CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV‑2 Helicase Nsp13

von Herasymenko, Oleksandra ; Silva, Madhushika ; Abu-Saleh, Abd Al-Aziz A. ; et al.

Journal of Chemical Information and Modeling. 65(13):6884-6898
- View full text at ACS Publications
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5
Active Learning-Guided Hit Optimization for the Leucine-Rich Repeat Kinase 2 WDR Domain Based on In Silico Ligand-Binding Affinities

von Gusev, Filipp ; Gutkin, Evgeny ; Gentile, Francesco ; et al.

Journal of Chemical Information and Modeling. 65(11):5706-5717
- View full text at ACS Publications
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6
CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson’s Disease Associated Protein

von Li, Fengling ; Ackloo, Suzanne ; Arrowsmith, Cheryl H. ; et al.

Journal of Chemical Information and Modeling. 64(22):8521-8536
- View full text at ACS Publications
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7
Fenofibrate and progression of retinopathy in adults with diabetes: the randomised placebo-controlled LENS trial

von David Preiss ; Jennifer Logue ; Emily Sammons ; et al.

Health Technology Assessment, Vol 30, Iss 41 (2026)

Schlagworte: humans; adult; diabetic retinopathy; fenofibrate; cost–benefit analysis; macular edema; quality-adjusted life-years; quality of life; retinal diseases; treatment outcome; health care costs; health services; visual acuity; Medical technology; R855-855.5
- View full text via DOI
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8
Protein–ligand data at scale to support machine learning

von Edwards, Aled M. ; Owen, Dafydd R. ; Zhang, Leili ; et al.

Nature Reviews Chemistry. 9(9):634-645
- Volltextverfügbarkeit prüfen (via ReDI)
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9
Enantioselective protein affinity selection mass spectrometry (E-ASMS)

von Xiaoyun Wang ; Jianxian Sun ; Shabbir Ahmad ; et al.

Nature Communications, Vol 17, Iss 1, Pp 1-10 (2025)

Schlagworte: Science
- View full text via DOI
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10
Small Molecule Screen Identifies Non-catalytic USP3 Chemical Handle

von Mann, Mandeep K. ; Wolf, Esther ; Silva, Madhushika ; et al.

ACS Omega. 9(1):917-924
- View full text at ACS Publications
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11
Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6

von Harding, Rachel J. ; Franzoni, Ivan ; Mann, Mandeep K. ; et al.

Journal of Medicinal Chemistry. 66(15):10273-10288
- View full text at ACS Publications
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12
Challenges and advances for huntingtin detection in cerebrospinal fluid: in support of relative quantification

von Harding, Rachel J. ; Xie, Yuanyun ; Caron, Nicholas S. ; et al.

Biomarker Research. 13(1)
- Zum Volltext in PubMed Central
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13
Immunological changes associated with the treatment of pneumonic tularaemia in marmosets

von Rachel E. Ireland ; Alejandro Nunez ; James D. Blanchard ; et al.

Frontiers in Cellular and Infection Microbiology, Vol 16 (2026)

Schlagworte: aerosol infection; ciprofloxacin; Francisella tularensis; innate immunity; interferon-gamma (IFN-γ); non-human primate model; Microbiology; QR1-502
- View full text via DOI
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14
USP7 deubiquitinase stabilizes FAN1 to support DNA crosslink repair and suppress CAG repeat expansion

von Giulio Collotta ; Marco Gatti ; Irina-Maria Ungureanu ; et al.

Nature Communications, Vol 17, Iss 1 (2026)

Schlagworte: Science
- View full text via DOI
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15
Regional Variation in Early Kidney Transplant Access Across Dialysis Facilities in 4 US Regions

von Jade Buford ; Mengyu Di ; Jessica L. Harding ; et al.

Kidney International Reports, Vol 11, Iss 3, Pp 103721- (2026)

Schlagworte: dialysis facility; evaluation start; kidney transplantation; kidney; waitlisting; Diseases of the genitourinary system. Urology; RC870-923
- View full text via DOI
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16
Music Ensemble: a large dataset on musicianship, cognition, and personality in musicians and nonmusicians

von Francesca Talamini ; Massimo Grassi ; Gianmarco Altoè ; et al.

Scientific Data, Vol 13, Iss 1 (2026)

Schlagworte: Science
- View full text via DOI
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17
Evidence-based blood tests for monitoring adults with chronic kidney disease stage G3 in primary care: rapid review, routine data analysis, and consensus study

von Martha M C Elwenspoek, PhD ; Rachel O’Donnell, MSc ; Catalina Lopez Manzano, MSc ; et al.

The Lancet Primary Care, Vol 2, Iss 2, Pp 100099- (2026)

Schlagworte: Public aspects of medicine; RA1-1270
- View full text via DOI
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18
A rapid evaluation of the reporting and publishing practices of patient and public involvement and engagement in health research within a UK university institute

von Hannah May Scott ; Lily Price ; Margaret Ogden ; et al.

Research Involvement and Engagement, Vol 12, Iss 1 (2026)

Schlagworte: PPIE; Literature review; Health research; Medicine; Medicine (General); R5-920
- View full text via DOI
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19
An innovative in silico model of the oral mucosa reveals the impact of extracellular spaces on chemical permeation through epithelium

von Edwards, Sean M. ; Harding, Amy L. ; Leedale, Joseph A. ; et al.

Schlagworte: Quantitative Biology - Tissues and Organs
- View full text via Arxiv
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20
Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection

von Mimi M. Hou ; Adam C. Harding ; Natalie M. Barber ; et al.

Nature Communications, Vol 16, Iss 1, Pp 1-13 (2025)

Schlagworte: Science
- View full text via DOI
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21
Divergent Trends by Patient Age in Racial Disparities in Kidney Transplant Access

von Jade Buford ; Jessica L. Harding ; Mengyu Di ; et al.

Kidney International Reports, Vol 10, Iss 8, Pp 2766-2777 (2025)

Schlagworte: kidney; kidney transplantation; multivariate analysis; waiting lists; Diseases of the genitourinary system. Urology; RC870-923
- View full text via DOI
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22
USP7 deubiquitinase stabilizes FAN1 to support DNA crosslink repair and suppress CAG repeat expansion.

von Collotta, Giulio ; Gatti, Marco ; Ungureanu, Irina-Maria ; et al.

Schlagworte: 3101 Biochemistry and Cell Biology; 31 Biological Sciences; Neurodegenerative; Rare Diseases; Huntington's Disease; Neurosciences; Genetics; Brain Disorders; 2.1 Biological and endogenous factors; Neurological
- View full text via BASE
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23
In-store beverage pricing and marketing before and after a sugar-sweetened beverage tax in Newfoundland and Labrador

von Kierra Dooley ; Daniel A. Zaltz ; Scott V. Harding ; et al.

Public Health Nutrition, Vol 29 (2026)

Schlagworte: Sugar-sweetened beverages; observational study; price; revenue; taxes; health promotion; marketing; Public aspects of medicine; RA1-1270; Nutritional diseases. Deficiency diseases; RC620-627
- View full text via DOI
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24
Recording and reporting of adverse events during a randomized controlled trial of cognitive behavioural therapy for insomnia (CBT-I) among cancer survivors

von Krista M. Greeley ; Rachel M. Lee ; Joshua Tulk ; et al.

Sleep Science and Practice, Vol 9, Iss 1, Pp 1-11 (2025)

Schlagworte: Insomnia; Cognitive behavioural therapy for insomnia; Cancer; Adverse events; Medicine
- View full text via DOI
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25
Structure–Activity Relationship of USP5 Inhibitors

von Mann, Mandeep K. ; Zepeda-Velázquez, Carlos A. ; González-Álvarez, Héctor ; et al.

Journal of Medicinal Chemistry. 64(20):15017-15036
- View full text at ACS Publications
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12 3 4 5 6 7 8 9 10 11 weiter »

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