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Treffer 1 - 25 von 3059, Suchdauer: 1.08s

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1
Development of a Dual Chemical Probe for the USP16 and HDAC6 Zinc-Finger Ubiquitin-Binding Domain

von Silva, Madhushika ; Mann, Mandeep ; Mirabi, Bijan ; et al.

Journal of Medicinal Chemistry. 69(5):5703-5711
- View full text at ACS Publications
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2
CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV‑2

von Herasymenko, Oleksandra ; Silva, Madhushika ; Correy, Galen J. ; et al.

Journal of Chemical Information and Modeling. 66(3):1566-1581
- View full text at ACS Publications
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3
Enabling Open Machine Learning of Deoxyribonucleic Acid-Encoded Library Selections to Accelerate the Discovery of Small Molecule Protein Binders

von Wellnitz, James ; Ahmad, Shabbir ; Bagale, Nabin ; et al.

Journal of Medicinal Chemistry. 68(20):21635-21648
- View full text at ACS Publications
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4
CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV‑2 Helicase Nsp13

von Herasymenko, Oleksandra ; Silva, Madhushika ; Abu-Saleh, Abd Al-Aziz A. ; et al.

Journal of Chemical Information and Modeling. 65(13):6884-6898
- View full text at ACS Publications
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5
Active Learning-Guided Hit Optimization for the Leucine-Rich Repeat Kinase 2 WDR Domain Based on In Silico Ligand-Binding Affinities

von Gusev, Filipp ; Gutkin, Evgeny ; Gentile, Francesco ; et al.

Journal of Chemical Information and Modeling. 65(11):5706-5717
- View full text at ACS Publications
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6
CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson’s Disease Associated Protein

von Li, Fengling ; Ackloo, Suzanne ; Arrowsmith, Cheryl H. ; et al.

Journal of Chemical Information and Modeling. 64(22):8521-8536
- View full text at ACS Publications
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7
Protein–ligand data at scale to support machine learning

von Edwards, Aled M. ; Owen, Dafydd R. ; Zhang, Leili ; et al.

Nature Reviews Chemistry. 9(9):634-645
- Volltextverfügbarkeit prüfen (via ReDI)
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8
Enantioselective protein affinity selection mass spectrometry (E-ASMS)

von Xiaoyun Wang ; Jianxian Sun ; Shabbir Ahmad ; et al.

Nature Communications, Vol 17, Iss 1, Pp 1-10 (2025)

Schlagworte: Science
- View full text via DOI
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9
Challenges and advances for huntingtin detection in cerebrospinal fluid: in support of relative quantification

von Harding, Rachel J. ; Xie, Yuanyun ; Caron, Nicholas S. ; et al.

Biomarker Research. 13(1)
- Zum Volltext in PubMed Central
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10
Regional Variation in Early Kidney Transplant Access Across Dialysis Facilities in 4 US Regions

von Jade Buford ; Mengyu Di ; Jessica L. Harding ; et al.

Kidney International Reports, Vol 11, Iss 3, Pp 103721- (2026)

Schlagworte: dialysis facility; evaluation start; kidney transplantation; kidney; waitlisting; Diseases of the genitourinary system. Urology; RC870-923
- View full text via DOI
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11
Small Molecule Screen Identifies Non-catalytic USP3 Chemical Handle

von Mann, Mandeep K. ; Wolf, Esther ; Silva, Madhushika ; et al.

ACS Omega. 9(1):917-924
- View full text at ACS Publications
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12
Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6

von Harding, Rachel J. ; Franzoni, Ivan ; Mann, Mandeep K. ; et al.

Journal of Medicinal Chemistry. 66(15):10273-10288
- View full text at ACS Publications
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13
Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection

von Mimi M. Hou ; Adam C. Harding ; Natalie M. Barber ; et al.

Nature Communications, Vol 16, Iss 1, Pp 1-13 (2025)

Schlagworte: Science
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14
An innovative in silico model of the oral mucosa reveals the impact of extracellular spaces on chemical permeation through epithelium

von Edwards, Sean M. ; Harding, Amy L. ; Leedale, Joseph A. ; et al.

Schlagworte: Quantitative Biology - Tissues and Organs
- View full text via Arxiv
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15
USP7 deubiquitinase stabilizes FAN1 to support DNA crosslink repair and suppress CAG repeat expansion.

von Collotta, Giulio ; Gatti, Marco ; Ungureanu, Irina-Maria ; et al.

Schlagworte: 3101 Biochemistry and Cell Biology; 31 Biological Sciences; Neurodegenerative; Rare Diseases; Huntington's Disease; Neurosciences; Genetics; Brain Disorders; 2.1 Biological and endogenous factors; Neurological
- View full text via BASE
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16
Divergent Trends by Patient Age in Racial Disparities in Kidney Transplant Access

von Jade Buford ; Jessica L. Harding ; Mengyu Di ; et al.

Kidney International Reports, Vol 10, Iss 8, Pp 2766-2777 (2025)

Schlagworte: kidney; kidney transplantation; multivariate analysis; waiting lists; Diseases of the genitourinary system. Urology; RC870-923
- View full text via DOI
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17
Ofsted experiences: performing inspection and suicidal ideations

von Harding, Rachel ; Clapham, Andrew

Journal of Education Policy ; page 1-21 ; ISSN 0268-0939 1464-5106
- View full text via BASE
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18
Effects of empagliflozin on quality of life and healthcare use and costs in chronic kidney disease: a health economic analysis of the EMPA-KIDNEY trialResearch in context

von Junwen Zhou ; Claire Williams ; Natalie Staplin ; et al.

EClinicalMedicine, Vol 85, Iss , Pp 103338- (2025)

Schlagworte: Chronic kidney disease (CKD); Empagliflozin; Quality-adjusted life-year (QALY); Health care use; Health care costs; Medicine (General); R5-920
- View full text via DOI
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19
Understanding the Needs of Moderators in Online Mental Health Forums: Realist Synthesis and Recommendations for Support

von Heather Robinson ; Millissa Booth ; Lauren Fothergill ; et al.

JMIR Mental Health, Vol 12, p e58891 (2025)

Schlagworte: Psychology; BF1-990
- View full text via DOI
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20
Recording and reporting of adverse events during a randomized controlled trial of cognitive behavioural therapy for insomnia (CBT-I) among cancer survivors

von Krista M. Greeley ; Rachel M. Lee ; Joshua Tulk ; et al.

Sleep Science and Practice, Vol 9, Iss 1, Pp 1-11 (2025)

Schlagworte: Insomnia; Cognitive behavioural therapy for insomnia; Cancer; Adverse events; Medicine
- View full text via DOI
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21
Beverage consumption among adults in Newfoundland and Labrador, Canada prior to the implementation of a sugar-sweetened beverage tax

von Daniel A. Zaltz ; Rachel Prowse ; Yanqing Yi ; et al.

BMC Public Health, Vol 25, Iss 1, Pp 1-11 (2025)

Schlagworte: Sugar-sweetened beverage tax; Health equity; Canada; Public aspects of medicine; RA1-1270
- View full text via DOI
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22
Structure–Activity Relationship of USP5 Inhibitors

von Mann, Mandeep K. ; Zepeda-Velázquez, Carlos A. ; González-Álvarez, Héctor ; et al.

Journal of Medicinal Chemistry. 64(20):15017-15036
- View full text at ACS Publications
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23
Vasopressor use after noncardiac surgery: an international observational study

von Abodun, Meriem ; Bouaoud, Souad ; Bouchenak, Kamel ; et al.

In British Journal of Anaesthesia July 2025
- View full text via DOI
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24
The Future of Gamma-Ray Experiments in the MeV-EeV Range

von Engel, Kristi ; Goodman, Jordan ; Huentemeyer, Petra ; et al.

Schlagworte: Astrophysics - High Energy Astrophysical Phenomena; Astrophysics - Instrumentation and Methods for Astrophysics
- View full text via Arxiv
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25
Synthesis and functional screening of novel inhibitors targeting the HDAC6 zinc finger ubiquitin-binding domain

von Geurs, Silke ; Staessens, Eleni ; Bredael, Kato ; et al.

In European Journal of Medicinal Chemistry 5 March 2025 285
- View full text via DOI
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