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Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity
von Hendricks, AE ; Bochukova, EG ; Marenne, G ; et al.
Schlagworte: Animals; Case-Control Studies; Chromogranins; Female; GTP-Binding Protein alpha Subunits; Gs; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Variation; Humans; Male; Mice; Models; Molecular; Mutation; Obesity; Morbid; Odds Ratio; Pediatric Obesity; Pedigree; Protein Conformation; Rodentia
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von Gregson, JM ; Freitag, DF ; Surendran, P ; et al.
504 ; 492
Schlagworte: Human genetics; coronary heart disease; darapladib; lipoprotein-associated phospholipase A2; target validation; CKDGen consortium; International Consortium for Blood Pressure; CHARGE inflammation working group; MICAD Exome consortium; EPIC-CVD consortium and the CHD Exome+ consortium
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von Scott, RA ; Freitag, DF ; Li, L ; et al.
Science Translational Medicine , 8 (341) , Article 341ra76. (2016)
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Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity
von Hendricks, AE ; Bochukova, EG ; Marenne, G ; et al.
ftqueenmaryuniv
Schlagworte: edu; info
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von Gregson, JM ; Freitag, DF ; Surendran, P ; et al.
Schlagworte: human genetics; target validation; coronary heart disease; lipoprotein-associated phospholipase A2; darapladib
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von Bodea, Corneliu A. ; Neale, Benjamin M. ; Ripke, Stephan ; et al.
Schlagworte: Genetic; Genetics (clinical)
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von Surendran, P ; Drenos, F ; Young, R ; et al.
1161 ; 1151
Schlagworte: CHARGE-Heart Failure Consortium; EchoGen Consortium; METASTROKE Consortium; GIANT Consortium; EPIC-InterAct Consortium; Lifelines Cohort Study; Wellcome Trust Case Control Consortium; Understanding Society Scientific Group; EPIC-CVD Consortium; CHARGE+ Exome Chip Blood Pressure Consortium; T2D-GENES Consortium; GoT2DGenes Consortium; ExomeBP Consortium; CHD Exome+ Consortium; Developmental Biology; 11 Medical And Health Sciences; 06 Biological Sciences
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von Tomaszewski, M ; Morris, AP ; Howson, JMM ; et al.
Schlagworte: Journal Article
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von Flannick, J ; Fuchsberger, C ; Mahajan, A ; et al.
Schlagworte: Journal Article
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von Jostins, Luke ; Ripke, Stephan ; Weersma, Rinse K. ; et al.
Schlagworte: Colitis; Ulcerative; Crohn Disease; Genetic Predisposition to Disease; Genome; Human; Haplotype; Inflammatory Bowel Disease; Mycobacterium; Mycobacterium Infection; Mycobacterium tuberculosi; Phenotype; Polymorphism; Single Nucleotide; Reproducibility of Result; Genome-Wide Association Study; Host-Pathogen Interaction; Multidisciplinary
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von Howson, JM ; Krause, S ; Stevens, H ; et al.
Schlagworte: info:eu-repo/classification/ddc
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von Davison, LJ ; Wallace, C ; Cooper, JD ; et al.
Schlagworte: info:eu-repo/classification/ddc
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von Plagnol, V ; Howson, JM ; Smyth, DJ ; et al.
Plagnol, V, Howson, JM, Smyth, DJ, Walker, N, Hafler, JP, Wallace, C, Stevens, H, Jackson, L, Simmonds, MJ, Type 1 Diabetes Genetics, C, Bingley, PJ, Gough, SC & Todd, JA 2011, 'Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases', PLOS Genetics, vol. 7(8):e1002216. https://doi.org/10.1371/journal.pgen.1002216
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von Howson, JM ; Stevens, H ; Smyth, DJ ; et al.
Howson, JM, Stevens, H, Smyth, DJ, Walker, N, Chandler, MA-M, Bingley, PJ & Todd, JA 2011, 'Evidence That HLA Class I and II Associations With Type 1 Diabetes, Autoantibodies to GAD and Autoantibodies to IA-2, Are Distinct', Diabetic Medicine, vol. 60, no. 10, pp. 2635 - 2644. https://doi.org/10.2337/db11-0131
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von Surendran, Praveen ; Drenos, Fotios ; Young, Robin ; et al.
Schlagworte: Blood Pressure; Genetic Predisposition to Disease; Genetic Variation; Genome-Wide Association Study; Genotype; Humans; Hypertension; Article
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von Freitag, DF ; Butterworth, AS ; Willeit, P ; et al.
Freitag, DF, Butterworth, AS, Willeit, P, Howson, JMM, Burgess, S, Kaptoge, S, Young, R, Ho, WK, Wood, AM, Sweeting, M, Spackman, S, Staley, JR, Ramond, A, Harshfield, E, Nielsen, SF, Grande, P, Lange, LA, Bown, MJ, Jones, GT, Scott, RA, Bevan, S, Porcu, E, Thorleifsson, G, Zeng, LY, Kessler, T, Nikpay, M, Do, R, Zhang, WH, Hopewell, JC, Kleber, M, Delgado, GE, Nelson, CP, Goel, A, Bis, JC, Dehghan, A, Ligthart, S, Smith, AV, Qu, LM, van 't Hof, FNG, de Bakker, PIW, Baas, AF, van Rij, A, Tromp, G, Kuivaniemi, H, Ritchie, MD, Verma, SS, Crawford, DC, Malinowski, J, de Andrade, M, Kullo, IJ, Peissig, PL, McCarty, CA, Bottinger, EP, Gottesman, O, Crosslin, DR, Carrell, DS, Rasmussen-Torvik, LJ, Pacheco, JA, Huang, J, Timpson, NJ, Kettunen, J, Ala-Korpela, M, Mitchell, GF, Parsa, A, Wilkinson, IB, Gorski, M, Li, Y, Franceschini, N, Keller, MF, Ganesh, SK, Langefeld, CD, Bruijn, L, Brown, MA, Evans, DM, Baltic, S, Ferreira, MA, Baurecht, H, Weidinger, S, Franke, A, Lubitz, SA, Muller-Nurasyid, M, Felix, J, Smith, NL, Sudman, M, Thompson, SD, Zeggini, E, Panoutsopoulou, K, Nalls, MA, Singleton, A, Polychronakos, C, Bradfield, JP, Hakonarson, H, Easton, DF, Thompson, D, Tomlinson, IP, Dunlop, M, Hemminki, K, Morgan, G, Eisen, T, Goldschmidt, H, Allan, JM, Henrion, M, Whiffin, N, Wang, YF, Chubb, D, Houlston, RS, Iles, MM, Bishop, DT, Law, MH, Hayward, NK, Luo, Y, Nejentsev, S, Barbalic, M, Crossman, D, Sanna, S, Soranzo, N, Markus, HS, Wareham, NJ, Rader, DJ, O Reilly, M, Assimes, T, Harris, TB, Hofman, B, Franco Duran, OH, Gudnason, V, Tracy, R, Psaty, BM, Farrall, M, Watkins, H, Hall, AS, Samani, NJ, Marz, W, Clarke, R, Collins, R, Kooner, JS, Chambers, JC, Kathiresan, S, McPherson, R, Erdmann, J, Kastrati, A, Schunkert, H, Stefansson, K, Thorsteinsdottir, U, Walston, JD, Tybjaerg-Hansen, A, Alam, DS, Majumder, AA, Di Angelantonio, E, Chowdhury, R, Nordestgaard, BG, Saleheen, D, Thompson, SG & Danesh, J 2015, 'Cardiometabolic effects of genetic upregulation of the interl
Schlagworte: dk/atira/pure/keywords/researchprograms/AFL001000/EMCNIHES016401; name=EMC NIHES-01-64-01; dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being; name=SDG 3 - Good Health and Well-being; article
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