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Treffer 1 - 25 von 642, Suchdauer: 1.33s

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1
Nemotron 3 Super: Open, Efficient Mixture-of-Experts Hybrid Mamba-Transformer Model for Agentic Reasoning

von NVIDIA ; Chandiramani, Aakshita ; Blakeman, Aaron ; et al.

Schlagworte: Machine Learning; Artificial Intelligence; Computation and Language
- View full text via Arxiv
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2
NVIDIA Nemotron 3: Efficient and Open Intelligence

von NVIDIA ; Blakeman, Aaron ; Grattafiori, Aaron ; et al.

Schlagworte: Computation and Language; Artificial Intelligence; Machine Learning
- View full text via Arxiv
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3
Nemotron 3 Nano: Open, Efficient Mixture-of-Experts Hybrid Mamba-Transformer Model for Agentic Reasoning

von NVIDIA ; Blakeman, Aaron ; Grattafiori, Aaron ; et al.

Schlagworte: Computation and Language; Artificial Intelligence; Machine Learning
- View full text via Arxiv
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4
Differentiating Gastric Cancers from Acid Peptic Diseases through Integrative Targeted Proteomics and Machine Learning Approaches

von Ramesh, Poornima ; Upadhyay, Shubham Sukerndeo ; Thomas, Sonet Daniel ; et al.

Journal of Proteome Research. 24(10):5159-5176
- View full text at ACS Publications
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5
Network pharmacology and metabolomics analysis of Tinospora cordifolia reveals BACE1 and MAOB as potential therapeutic targets for neuroprotection in Alzheimer’s disease

von S. Amrutha ; Chandran S. Abhinand ; Shubham Sukerndeo Upadhyay ; et al.

Scientific Reports, Vol 15, Iss 1, Pp 1-23 (2025)

Schlagworte: Tinospora cordifolia; Medhya rasayana; Untargeted metabolomics; Neuroprotection; Therapeutic targets; Medicine; Science
- View full text via DOI
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6
Glycyrrhizic Acid Attenuates Aβ42-Induced Neurodegeneration Through Coordinated Regulation of Oxidative Stress, Synaptic Markers, and Key Alzheimer’s Signaling Pathways

von S. Amrutha ; Thottethodi Subrahmanya Keshava Prasad ; Prashant Kumar Modi

Cells, Vol 15, Iss 5, p 436 (2026)

Schlagworte: glycyrrhizic acid; amyloid-beta; mitochondrial dysfunction; neuroprotection; apoptosis; Cytology; QH573-671
- View full text via DOI
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7
Impact of Curcumin on the IL-17A-Mediated p53-Fibrinolytic System: Mouse Proteomics and Integrated Human Fibrosis scRNAseq Insights

von Gouda, Mahesh Manjunath ; Balaya, Rex Devasahayam Arokia ; Modi, Prashant Kumar ; et al.

Inflammation. 48(4):1957-1973
- Zum Volltext (via ReDI)
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8
Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

von Hay, Simon I ; Ong, Kanyin Liane ; Santomauro, Damian F ; et al.

In The Lancet 18-24 October 2025 406(10513):1873-1922
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9
Phosphoproteome-Entailed Kinase–Substrate Landscape of Human–DENV-2 Interaction

von Ayisha A. Jabbar ; Vineetha Shaji ; Akash Anil ; et al.

International Journal of Molecular Sciences ; Volume 27 ; Issue 6 ; Pages: 2718

Schlagworte: dengue virus; kinase–substrate phosphomotifs; phosphorylation; protein–protein interaction; molecular docking
- View full text via BASE
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10
Dissecting Plasmodium yoelii Pathobiology: Proteomic Approaches for Decoding Novel Translational and Post-Translational Modifications

von Devasahayam Arokia Balaya Rex ; Arun H. Patil ; Prashant Kumar Modi ; et al.

ACS Omega, Vol 7, Iss 10, Pp 8246-8257 (2022)

Schlagworte: Chemistry; QD1-999
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11
Exploration of Asparagus racemosus Willd for Alzheimer’s Disease Through Integrated Metabolomics and Network Pharmacology Analyses Targeting BACE1 Protein

von Shaji, Vineetha ; Amrutha, S. ; Pervaje, Ravishankar ; et al.

Neurochemical Research. 50(3)
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12
Identification of Molecular Network Associated with Neuroprotective Effects of Yashtimadhu (Glycyrrhiza glabra L.) by Quantitative Proteomics of Rotenone-Induced Parkinson’s Disease Model

von Gayathree Karthikkeyan ; Mohd. Altaf Najar ; Ravishankar Pervaje ; et al.

ACS Omega, Vol 5, Iss 41, Pp 26611-26625 (2020)

Schlagworte: Chemistry; QD1-999
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13
Comparative Metabolomics and Network Pharmacology Analysis Reveal Shared Neuroprotective Mechanisms of Bacopa monnieri (L.) Wettst and Centella asiatica (L.) Urb

von Parate, Sakshi Sanjay ; Upadhyay, Shubham Sukerndeo ; S., Amrutha ; et al.

Molecular Neurobiology. 61(12):10956-10978
- Zum Volltext (via ReDI)
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14
Deep Metabolomic Profiling Reveals Alterations in Fatty Acid Synthesis and Ketone Body Degradations in Spermatozoa and Seminal Plasma of Astheno-Oligozoospermic Bulls

von Mohua Dasgupta ; Arumugam Kumaresan ; Kaustubh Kishor Saraf ; et al.

Frontiers in Veterinary Science, Vol 8 (2022)

Schlagworte: metabolomics; spermatozoa; seminal plasma; dairy bulls; mass spectrometry; semen quality; Veterinary medicine; SF600-1100
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15
Tyrosine Phosphorylation Profiling Revealed the Signaling Network Characteristics of CAMKK2 in Gastric Adenocarcinoma

von Mohd. Altaf Najar ; Mohammad Arefian ; David Sidransky ; et al.

Frontiers in Genetics, Vol 13 (2022)

Schlagworte: CAMKK2; mass spectrometry; gastric cancer; PTK2; STAT3; Genetics; QH426-470
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16
Data on dose-dependent cytotoxicity of rotenone and neuroprotection conferred by Yashtimadhu (Glycyrrhiza glabra L.) in an in vitro Parkinson's disease model

von Gayathree Karthikkeyan ; Ashwini Prabhu ; Ravishankar Pervaje ; et al.

Data in Brief, Vol 39, Iss , Pp 107535- (2021)

Schlagworte: Neurodegeneration; Complementary and alternative medicine; Ayurveda; Actionable molecules; Computer applications to medicine. Medical informatics; R858-859.7; Science (General); Q1-390
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17
Molecular Profiling Associated with Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2)-Mediated Carcinogenesis in Gastric Cancer

von Najar, Mohd. Altaf ; Modi, Prashant Kumar ; Ramesh, Poornima ; et al.

Journal of Proteome Research. 20(5):2687-2703
- View full text at ACS Publications
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18
Proteomics Analysis Revealed the Importance of Inflammation-Mediated Downstream Pathways and the Protective Role of Curcumin in Bleomycin-Induced Pulmonary Fibrosis in C57BL/6 Mice

von Gouda, Mahesh Manjunath ; Rex, D. A. B. ; ES, Sindhu Priya ; et al.

Journal of Proteome Research. 19(8):2950-2963
- View full text at ACS Publications
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19
CusVarDB: A tool for building customized sample-specific variant protein database from next-generation sequencing datasets [version 2; peer review: 2 approved]

von Sandeep Kasaragod ; Varshasnata Mohanty ; Ankur Tyagi ; et al.

F1000Research, Vol 9 (2020)

Schlagworte: Medicine; Science
- View full text via DOI
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20
Discovery of LNP1892: A Precision Calcimimetic for the Treatment of Secondary Hyperparathyroidism

von Shukla, Manojkumar R. ; Sadasivam, Gayathri ; Sarde, Ankush ; et al.

Journal of Medicinal Chemistry. 66(14):9418-9444
- View full text at ACS Publications
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21
Discovery of a Novel Potent and Selective Calcium Release-Activated Calcium Channel Inhibitor: 2,6-Difluoro‑N‑(2′-methyl-3′-(4-methyl-5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-[1,1′-biphenyl]-4-yl)benzamide. Structure–Activity Relationship and Preclinical Characterization

von Khedkar, Nilesh Raghunath ; Irlapatti, Nageswara Rao ; Dadke, Disha ; et al.

Journal of Medicinal Chemistry. 64(23):17004-17030
- View full text at ACS Publications
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22
Discovery of a Potent and Selective PI3Kδ Inhibitor (S)‑2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl‑4H‑quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models

von Shukla, Manojkumar R. ; Patra, Sukanya ; Verma, Mahip ; et al.

Journal of Medicinal Chemistry. 63(23):14700-14723
- View full text at ACS Publications
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23
Discovery of Potent, Selective, and State-Dependent NaV1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure–Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides

von Ramdas, Vidya ; Talwar, Rashmi ; Kanoje, Vijay ; et al.

Journal of Medicinal Chemistry. 63(11):6107-6133
- View full text at ACS Publications
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24
Bacopa monnieri confers neuroprotection by influencing signaling pathways associated with interleukin 4, 13 and extracellular matrix organization in Alzheimer's disease: A proteomics-based perspective

von Palollathil, Akhina ; Najar, Mohd Altaf ; Amrutha, S. ; et al.

In Neurochemistry International November 2024 180
- View full text via DOI
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25
Immunomodulation of streptozotocin induced Type 1 diabetes mellitus in mouse model by Macrophage migration inhibitory factor-2 (MIF-2) homologue of human lymphatic filarial parasite, Wuchereria bancrofti

von Singh, Ishwar ; Hoti, S.L. ; Chauhan, Nikhil ; et al.

In Acta Tropica April 2024 252
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