1
Arginine depletion potentiates standard-of-care chemo-immunotherapy in preclinical models of high-risk neuroblastoma

von Kimberley M. Hanssen ; Jayne Murray ; Ruby Pandher ; et al.

Journal of Experimental & Clinical Cancer Research, Vol 44, Iss 1, Pp 1-16 (2025)

Schlagworte: Neuroblastoma; Arginine; Arginase; Metabolism; Preclinical testing; Patient-derived xenografts; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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2
The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma

von Mujahid Azfar ; Weiman Gao ; Chris Van den Haute ; et al.

Molecular Oncology, Vol 19, Iss 3, Pp 913-936 (2025)

Schlagworte: neuroblastoma; DFMO; ATP13A3; AMXT 1501; polyamine depletion; polyamine transport inhibitor; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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3
Combined inhibition of histone methyltransferases EZH2 and DOT1L is an effective therapy for neuroblastoma

von Janith A. Seneviratne ; Daenikka Ravindrarajah ; Daniel R. Carter ; et al.

Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)

Schlagworte: biomarkers; cancer biology; chromatin modifications and dynamics; epigenetics; molecular biology; neuroblastoma; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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4
Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas

von Aaminah Khan ; Laura D. Gamble ; Dannielle H. Upton ; et al.

Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

Schlagworte: Science
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5
Direct targeted therapy for MLL‐fusion‐driven high‐risk acute leukaemias

von Sandra Cantilena ; Luca Gasparoli ; Deepali Pal ; et al.

Clinical and Translational Medicine, Vol 12, Iss 6, Pp n/a-n/a (2022)

Schlagworte: leukaemia; MLL‐fusion; mouse models; precision medicine; targeted therapy; Medicine (General); R5-920
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6
Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

von Anahid Ehteda ; Sandy Simon ; Laura Franshaw ; et al.

Cell Reports, Vol 35, Iss 2, Pp 108994- (2021)

Schlagworte: DIPG; brainstem glioma; H3K27M; facilitates chromatin transcription complex; HDAC; EZH2; Biology (General); QH301-705.5
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7
Additional file 6 of Arginine depletion potentiates standard-of-care chemo-immunotherapy in preclinical models of high-risk neuroblastoma

von Kimberley M. Hanssen ; Jayne Murray ; Ruby Pandher ; et al.

Schlagworte: Biochemistry; Medicine; Cell Biology; Pharmacology; Cancer; Virology; Information Systems not elsewhere classified; Neuroblastoma; Arginine; Arginase; Metabolism; Preclinical testing; Patient-derived xenografts
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8
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11
Additional file 2 of Arginine depletion potentiates standard-of-care chemo-immunotherapy in preclinical models of high-risk neuroblastoma

von Kimberley M. Hanssen ; Jayne Murray ; Ruby Pandher ; et al.

Schlagworte: Biochemistry; Medicine; Cell Biology; Pharmacology; Cancer; Virology; Information Systems not elsewhere classified; Neuroblastoma; Arginine; Arginase; Metabolism; Preclinical testing; Patient-derived xenografts
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12
Additional file 3 of Arginine depletion potentiates standard-of-care chemo-immunotherapy in preclinical models of high-risk neuroblastoma

von Kimberley M. Hanssen ; Jayne Murray ; Ruby Pandher ; et al.

Schlagworte: Biochemistry; Medicine; Cell Biology; Pharmacology; Cancer; Virology; Information Systems not elsewhere classified; Neuroblastoma; Arginine; Arginase; Metabolism; Preclinical testing; Patient-derived xenografts
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13
Additional file 5 of Arginine depletion potentiates standard-of-care chemo-immunotherapy in preclinical models of high-risk neuroblastoma

von Kimberley M. Hanssen ; Jayne Murray ; Ruby Pandher ; et al.

Schlagworte: Biochemistry; Medicine; Cell Biology; Pharmacology; Cancer; Virology; Information Systems not elsewhere classified; Neuroblastoma; Arginine; Arginase; Metabolism; Preclinical testing; Patient-derived xenografts
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14
Additional file 4 of Arginine depletion potentiates standard-of-care chemo-immunotherapy in preclinical models of high-risk neuroblastoma

von Kimberley M. Hanssen ; Jayne Murray ; Ruby Pandher ; et al.

Schlagworte: Biochemistry; Medicine; Cell Biology; Pharmacology; Cancer; Virology; Information Systems not elsewhere classified; Neuroblastoma; Arginine; Arginase; Metabolism; Preclinical testing; Patient-derived xenografts
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15
Additional file 1 of Arginine depletion potentiates standard-of-care chemo-immunotherapy in preclinical models of high-risk neuroblastoma

von Kimberley M. Hanssen ; Jayne Murray ; Ruby Pandher ; et al.

Schlagworte: Biochemistry; Medicine; Cell Biology; Pharmacology; Cancer; Virology; Information Systems not elsewhere classified; Neuroblastoma; Arginine; Arginase; Metabolism; Preclinical testing; Patient-derived xenografts
- View full text via BASE
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16
The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma.

von Azfar, Mujahid ; Gao, Weiman ; Van den Haute, Chris ; et al.

Molecular Oncology. Mar2025, Vol. 19 Issue 3, p913-936. 24p.
- Zum Volltext in PubMed Central
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17
A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

von Somers, Klaartje ; Wen, Victoria W. ; Middlemiss, Shiloh M. C. ; et al.

Oncogene. 38(20):3824-3842
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18
Direct targeted therapy for MLL-fusion-driven high-risk acute leukaemias.

von Cantilena, Sandra ; Gasparoli, Luca ; Pal, Deepali ; et al.

Schlagworte: Article
- Zum Volltext über OAIster
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19
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20
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21
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