1
Immune checkpoint inhibition increases antigen-specific T cell response in head and neck cancer

von Patrick J. Schuler ; Franziska Oliveri ; Lisa Puntigam ; et al.

Scientific Reports, Vol 16, Iss 1 (2026)

Schlagworte: Anti-LAG-3 (Lymphocyte activation gene 3); Anti-PD-1 (Programmed death-1, aPD-1); Anti-TIM-3 (T cell immunoglobulin and mucin-domain containing-3); Head and neck cancer (HNC); Immune checkpoints; Melanoma-associated antigen (MAGE); Medicine; Science
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2
Newly Identified Transcriptomic Biomarkers and Gene Signature of Pathological Complete Response to Induction Chemoimmunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

von Jian‐Guo Zhou ; Markus Eckstein ; Haitao Wang ; et al.

MedComm, Vol 7, Iss 1, Pp n/a-n/a (2026)

Schlagworte: head and neck squamous cell carcinoma; immunotherapy; induction therapy; pathological complete response; transcriptomic biomarkers; Medicine
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3
Randomized clinical efficacy and safety study of peltopepimut-S plus cemiplimab compared to cemiplimab alone in patients with recurrent/metastatic HPV16-positive head and neck cancer

von Marshall Posner ; Erminia Massarelli ; Lisa Licitra ; et al.

Journal for ImmunoTherapy of Cancer, Vol 13, Iss 9 (2025)

Schlagworte: Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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4
Characterization of the adaptive immune response in a mouse model for HPV-positive head and neck squamous cell carcinoma with implications to human disease

von Franziska Oliveri ; Linda Neher ; Ronja Pscheid ; et al.

Cancer Immunology, Immunotherapy, Vol 74, Iss 2, Pp 1-8 (2025)

Schlagworte: Head and neck cancer; HPV; Immune checkpoints; Tumor-infiltrating lymphocytes; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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5
5-Aza-2′-deoxycytidin (Decitabine) increases cancer-testis antigen expression in head and neck squamous cell carcinoma and modifies immune checkpoint expression, especially in CD39-positive CD8 and CD4 T cells

von Adrian Fehn ; Adrian von Witzleben ; Ayla Grages ; et al.

Neoplasia: An International Journal for Oncology Research, Vol 59, Iss , Pp 101086- (2025)

Schlagworte: OPSCC; HPV; Immune-Checkpoint-Molecules; DNA-Methylation; Cancer Testis Antigens; Decitabine; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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6
Regional outcome disparities in German head and neck cancer patients: Shorter survival in Eastern Germany

von Julius M. Vahl ; Gabriele Nagel ; Tsima Abou Kors ; et al.

Cancer Medicine, Vol 12, Iss 23, Pp 21426-21435 (2023)

Schlagworte: age; cancer registry data; demographic change; socioeconomic health disparity; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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7
Demographics and access to head and neck cancer care in rural areas compared to urban areas in Germany

von Julius M. Vahl ; Gabriele Nagel ; Ayla Grages ; et al.

Cancer Medicine, Vol 12, Iss 18, Pp 18826-18836 (2023)

Schlagworte: demographic change; East Germany; industrial country; peripheral region; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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8
Liquid biopsy: an examination of platelet RNA obtained from head and neck squamous cell carcinoma patients for predictive molecular tumor markers

von Lisa T. Huber ; Johann M. Kraus ; Jasmin Ezić ; et al.

Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 3, Pp 422-446 (2023)

Schlagworte: tumor educated platelets; liquid biopsy; head and neck; Internal medicine; RC31-1245
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9
Quantification of human papillomavirus cell-free DNA from low-volume blood plasma samples by digital PCR

von Fabian Rosing ; Matthias Meier ; Lea Schroeder ; et al.

Microbiology Spectrum, Vol 12, Iss 7 (2024)

Schlagworte: HPV; liquid biopsy; digital PCR; OPC; cfDNA; early detection; Microbiology; QR1-502
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10
Multi-omics analysis of overexpressed tumor-associated proteins: gene expression, immunopeptide presentation, and antibody response in oropharyngeal squamous cell carcinoma, with a focus on cancer-testis antigens

von Tsima Abou Kors ; Matthias Meier ; Lena Mühlenbruch ; et al.

Frontiers in Immunology, Vol 15 (2024)

Schlagworte: oropharyngeal squamous cell carcinoma (OPSCC); HLA; cancer testis antigens (CTA); tumor-associated peptide (TAP); antibody response (AR); Immunologic diseases. Allergy; RC581-607
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11
Medikamentöse Tumortherapie von Kopf-Hals-Tumoren: zwischen Standardisierung und Personalisierung

von Laban, Simon

HNO. 74(2):97-109
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12
Die 9. Ausgabe der TNM-Klassifikation nach UICC

von Sauter, Christina ; Laban, Simon ; Hoffmann, Thomas K. ; et al.

HNO. :1-5
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13
Treatment regimens for laryngeal and hypopharyngeal squamous cell carcinoma: a “real life” multicenter study of 2307 patients

von Knopf, Andreas ; Ketterer, Manuel Christoph ; Hoffmann, Thomas K. ; et al.

European Archives of Oto-Rhino-Laryngology: and Head & Neck. 282(12):6609-6621
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14
Surgery of T1/2 N0 M0 glottic cancer results in a better laryngeal preservation time compared to radiotherapy in a large German patient cohort

von Ketterer, Manuel Christoph ; Hoffmann, Thomas K. ; Laban, Simon ; et al.

European Archives of Oto-Rhino-Laryngology: and Head & Neck. 282(12):6645-6653
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15
Machine Learning-assisted immunophenotyping of peripheral blood identifies innate immune cells as best predictor of response to induction chemo-immunotherapy in head and neck squamous cell carcinoma – knowledge obtained from the CheckRad-CD8 trial

von Markus Hecht ; Benjamin Frey ; Udo S. Gaipl ; et al.

Neoplasia: An International Journal for Oncology Research, Vol 49, Iss , Pp 100953- (2024)

Schlagworte: Chemotherapy; Immunotherapy; HNSCC; Induction therapy; Immune phenotyping; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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16
Identification of B Cell Subpopulations with Pro- and Anti-Tumorigenic Properties in an Immunocompetent Mouse Model of Head and Neck Squamous Cell Carcinoma

von Michael Sonntag ; Sandra Stanojevic ; Simon Laban ; et al.

Cells, Vol 14, Iss 1, p 20 (2024)

Schlagworte: B cells; HNSCC; germinal centers; adenosine; immunocompetent mouse model; Cytology; QH573-671
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17
Treatment dependent impact of plasma-derived exosomes from head and neck cancer patients on the epithelial-to-mesenchymal transition

von Linda Hofmann ; Marie Waizenegger ; Ralph Röth ; et al.

Frontiers in Oncology, Vol 12 (2023)

Schlagworte: exosomes; HNSCC; EMT; conventional therapy; recurrence; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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18
Comparative effectiveness trial of transoral head and neck surgery followed by adjuvant radio(chemo)therapy versus primary radiochemotherapy for oropharyngeal cancer (TopROC)

von Lara Bußmann ; Simon Laban ; Claus Wittekindt ; et al.

BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)

Schlagworte: Head and neck cancer; Oropharynx; Radiotherapy; Transoral surgery; Survival; Quality of life; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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19
Immuntherapie von Kopf-Hals-Tumoren

von von Witzleben, Adrian ; Döscher, Johannes ; K. Hoffmann, Thomas ; et al.

InFo Hämatologie + Onkologie: Interdisziplinäre Fortbildung von Ärzten für Ärzte. 28(6):18-23
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20
Comparison of plasma- and saliva-derived exosomal miRNA profiles reveals diagnostic potential in head and neck cancer

von Linda Hofmann ; Tsima Abou Kors ; Jasmin Ezić ; et al.

Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Schlagworte: exosomes; miRNA; HNSCC; liquid biopsy; plasma; saliva; Biology (General); QH301-705.5
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21
Cargo and Functional Profile of Saliva-Derived Exosomes Reveal Biomarkers Specific for Head and Neck Cancer

von Linda Hofmann ; Valentin Medyany ; Jasmin Ezić ; et al.

Frontiers in Medicine, Vol 9 (2022)

Schlagworte: exosomes; head and neck squamous cell carcinoma (HNSCC); saliva; liquid biopsy; miRNA; Medicine (General); R5-920
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22
Changes in Gene Expression Patterns in the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Under Chemoradiotherapy Depend on Response

von Johannes Doescher ; Adrian von Witzleben ; Konstantinos Boukas ; et al.

Frontiers in Oncology, Vol 12 (2022)

Schlagworte: head and neck squamous cell carcinoma; chemoradiotherapy; tumor microenvironment; tissue resident memory T cells; gene set enrichment; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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23
Differential Requirement of Vav Proteins for Btk-dependent and –Independent Signaling During B Cell Development

von Annika C. Betzler ; Sebastian Kieser ; Katja Fiedler ; et al.

Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Schlagworte: BTK; bruton’s tyrosine kinase; VAV; B cell development; Ca2+ siganling; secondary lymphoid organs; Biology (General); QH301-705.5
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24
Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in locally advanced head and neck cancer

von Udo S Gaipl ; Arndt Hartmann ; Jian-Guo Zhou ; et al.

Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)

Schlagworte: Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
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25
CD3 and PD-L1 tissue expression have synergistic value in head and neck squamous cell carcinoma prognosis

von Witzleben, Adrian v. ; Remark, Romain ; Idel, Christian ; et al.

In Translational Oncology June 2026 68
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