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1
Safety and efficacy of combining midostaurin and gemtuzumab ozogamicin with induction chemotherapy in FLT3-mutated AML

von Nigel Russell ; Jad Othman ; Oliver Cumming ; et al.

Blood Advances, Vol 9, Iss 24, Pp 6455-6466 (2025)

Schlagworte: Specialties of internal medicine; RC581-951
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2
Adaptive clinical trial of AZD7442 and SARS-CoV-2 vaccination in immunosuppressed patients highly vulnerable to infection with SARS-CoV-2 virus (RAPID-PROTECTION): protocol for a multicentre, interventional open-label, randomised controlled trial

von Ernest Choy ; Kerenza Hood ; Emma Thomas-Jones ; et al.

BMJ Open, Vol 15, Iss 1 (2025)

Schlagworte: Medicine
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3
Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis

von Zijian Fang ; Giuditta Corbizi Fattori ; Thomas McKerrell ; et al.

Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)

Schlagworte: Science
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4
P503: A RANDOMISED TRIAL OF MOLECULAR MONITORING VERSUS STANDARD CLINICAL CARE IN YOUNGER ADULTS WITH ACUTE MYELOID LEUKAEMIA: RESULTS FROM THE UK NCRI AML17 AND AML19 STUDIES

von Nicola Potter ; Jelena Jovanovic ; Adam Ivey ; et al.

HemaSphere, Vol 7, p e345570d (2023)

Schlagworte: Diseases of the blood and blood-forming organs; RC633-647.5
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5
S131: A RANDOMISED ASSESSMENT OF THE SEQUENTIAL ADDITION OF THE KINASE INHIBITOR QUIZARTINIB TO INTENSIVE CHEMOTHERAPY IN OLDER ACUTE MYELOID LEUKAEMIA (AML) PATIENTS: RESULTS FROM THE NCRI AML18 TRIAL

von Steven Knapper ; Abin Thomas ; Sophie King ; et al.

HemaSphere, Vol 7, p e0819670 (2023)

Schlagworte: Diseases of the blood and blood-forming organs; RC633-647.5
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6
P484: GEMTUZUMAB-BASED INDUCTION CHEMOTHERAPY COMBINED WITH MIDOSTAURIN FOR FLT3 MUTATED AML. UPDATED TOXICITY AND INTERIM SURVIVAL ANALYSIS FROM THE NCRI AML19V2 'MIDOTARG' PILOT TRIAL

von Nigel Russell ; Oliver Cumming ; Jad Othman ; et al.

HemaSphere, Vol 7, p e13145db (2023)

Schlagworte: Diseases of the blood and blood-forming organs; RC633-647.5
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7
P863: AN OPEN-LABEL PHASE I/IIA STUDY TO EVALUATE THE SAFETY AND EFFICACY OF CCS1477 AS MONOTHERAPY AND IN COMBINATION WITH POMALIDOMIDE/DEXAMETHASONE IN RELAPSED/REFRACTORY MULTIPLE MYELOMA

von Emma Searle ; Jim Cavet ; Steven Knapper ; et al.

HemaSphere, Vol 7, p e54143bc (2023)

Schlagworte: Diseases of the blood and blood-forming organs; RC633-647.5
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8
S134: FLAG-IDA COMBINED WITH GEMTUZUMAB OZOGAMICIN (GO) REDUCED MRD LEVELS AND IMPROVED OVERALL SURVIVAL IN NPM1MUT AML INDEPENDENT OF FLT3 AND MRD STATUS, RESULTS FROM THE AML19 TRIAL

von Nigel Russell ; Jad Othman ; Richard Dillon ; et al.

HemaSphere, Vol 7, p e252478c (2023)

Schlagworte: Diseases of the blood and blood-forming organs; RC633-647.5
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9
S168: PELABRESIB (CPI-0610) MONOTHERAPY IN PATIENTS WITH HIGH-RISK ESSENTIAL THROMBOCYTHEMIA REFRACTORY OR INTOLERANT TO HYDROXYUREA: PRELIMINARY RESULTS FROM MANIFEST STUDY

von Francesco Passamonti ; Andrea Patriarca ; Steven Knapper ; et al.

HemaSphere, Vol 7, p e9927843 (2023)

Schlagworte: Diseases of the blood and blood-forming organs; RC633-647.5
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10
Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia

von Paul Milne ; Charlotte Wilhelm-Benartzi ; Michael R. Grunwald ; et al.

Blood Advances, Vol 3, Iss 20, Pp 3052-3061 (2019)

Schlagworte: Specialties of internal medicine; RC581-951
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11
CPX-351 vs daunorubicin, cytarabine, and gemtuzumab ozogamicin in older adults with non–adverse-risk AML: the NCRI AML18 trial

von Knapper, Steven ; Dillon, Laura W. ; Babu, Malavika ; et al.

In Blood 5 March 2026 147(10):1048-1057
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12
Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A

von Brierley, Charlotte K. ; Yip, Bon Ham ; Orlando, Giulia ; et al.

Nature Genetics. 57(6):1478-1492
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13
Combining quizartinib with intensive chemotherapy for older patients with newly diagnosed AML: results of the UK NCRI AML18 trial

von Knapper, Steven ; Thomas, Abin ; Hills, Robert K. ; et al.

In Blood June 2026
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14
A revised prognostic model for patients with acute myeloid leukemia and first relapse

von van der Maas, Niek G. ; Breems, Dimitri ; Klerk, Clara P. W. ; et al.

In Blood Advances April 2025
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15
Venetoclax–based low intensity therapy in molecular failure of NPM1-mutated AML

von Jimenez-Chillon, Carlos ; Othman, Jad ; Taussig, David ; et al.

In Blood Advances 23 January 2024 8(2):343-352
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16
The FLAM regimen: revisiting time sequential induction therapy for patients with poor-risk acute myeloid leukemia

von Steven Knapper

Haematologica, Vol 100, Iss 9 (2015)

Schlagworte: Diseases of the blood and blood-forming organs; RC633-647.5
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17
Fractionated vs single-dose gemtuzumab ozogamicin with determinants of benefit in older patients with AML: the UK NCRI AML18 trial

von Freeman, Sylvie D. ; Thomas, Abin ; Thomas, Ian ; et al.

In Blood 16 November 2023 142(20):1697-1707
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18
The topoisomerase II inhibitor voreloxin causes cell cycle arrest and apoptosis in myeloid leukemia cells and acts in synergy with cytarabine

von Elisabeth J. Walsby ; Steven J. Coles ; Steven Knapper ; et al.

Haematologica, Vol 96, Iss 3 (2011)

Schlagworte: Diseases of the blood and blood-forming organs; RC633-647.5
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19
FLT3 inhibitors as MRD-guided salvage treatment for molecular failure in FLT3 mutated AML

von Othman, Jad ; Potter, Nicola ; Mokretar, Katya ; et al.

Leukemia. 37(10):2066-2072
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20
Randomized evaluation of quizartinib and low-dose ara-C vs low-dose ara-C in older acute myeloid leukemia patients

von Dennis, Mike ; Thomas, Ian F. ; Ariti, Cono ; et al.

In Blood Advances 28 December 2021 5(24):5621-5625
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21
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22
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

von Aban, Marites ; Abayomi, Fatola ; Abeyskera, Kushala ; et al.

In The Lancet 9-15 January 2021 397(10269):99-111
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23
Results of a national UK physician reported survey of COVID-19 infection in patients with a myeloproliferative neoplasm

von Salisbury, Richard A. ; Curto-Garcia, Natalia ; O’Sullivan, Jennifer ; et al.

Leukemia. 35(8):2424-2430
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24
Molecular MRD status and outcome after transplantation in NPM1-mutated AML

von Dillon, Richard ; Hills, Robert ; Freeman, Sylvie ; et al.

In Blood 27 February 2020 135(9):680-688
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25
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