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1
Discovery of (R)‑8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4‑b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3H)‑one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies

von Wang, Hui-Ling ; Andrews, Kristin L. ; Booker, Shon K. ; et al.

Journal of Medicinal Chemistry. 62(3):1523-1540
- View full text at ACS Publications
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2
Habitable zone predictions and how to test them

von Ramirez, Ramses M. ; Abbot, Dorian S. ; Fujii, Yuka ; et al.

Schlagworte: Astrophysics - Earth and Planetary Astrophysics
- View full text via Arxiv
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3
Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors

von Pettus, Liping H. ; Andrews, Kristin L. ; Booker, Shon K. ; et al.

Journal of Medicinal Chemistry. 59(13):6407-6430
- View full text at ACS Publications
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4
Systematic Study of the Glutathione (GSH) Reactivity of N‑Arylacrylamides: 1. Effects of Aryl Substitution

von Cee, Victor J. ; Volak, Laurie P. ; Chen, Yuping ; et al.

Journal of Medicinal Chemistry. 58(23):9171-9178
- View full text at ACS Publications
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5
Discovery and in Vivo Evaluation of (S)‑N‑(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)‑9H‑purin-6-amine (AMG319) and Related PI3Kδ Inhibitors for Inflammation and Autoimmune Disease

von Cushing, Timothy D. ; Hao, Xiaolin ; Shin, Youngsook ; et al.

Journal of Medicinal Chemistry. 58(1):480-511
- View full text at ACS Publications
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6
Discovery of Pyridazinopyridinones as Potent and Selective p38 Mitogen-Activated Protein Kinase Inhibitors

von Wu, Bin ; Wang, Hui-Ling ; Pettus, Liping ; et al.

Journal of Medicinal Chemistry. 53(17):6398-6411
- View full text at ACS Publications
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7
Discovery and Evaluation of 7-Alkyl-1,5-bis-aryl-pyrazolopyridinones as Highly Potent, Selective, and Orally Efficacious Inhibitors of p38α Mitogen-Activated Protein Kinase ⊥ Atomic coordinates and structure factors for crystal structure of compound 3d with p38α can be accessed using PDB code 3LHJ.

von Pettus, Liping H. ; Wurz, Ryan P. ; Xu, Shimin ; et al.

Journal of Medicinal Chemistry. 53(7):2973-2985
- View full text at ACS Publications
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8
Vector-borne and other pathogens of potential relevance disseminated by relocated cats

von Maggi, Ricardo Guillermo ; Halls, Vicky ; Krämer, Friederike ; et al.

Parasites & Vectors. 15(1)
- Zum Volltext in PubMed Central
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9
New Antimitotic Agents with Activity in Multi-Drug-Resistant Cell Lines and in Vivo Efficacy in Murine Tumor Models

von Szczepankiewicz, Bruce G. ; Liu, Gang ; Jae, Hwan-Soo ; et al.

Journal of Medicinal Chemistry. 44(25):4416-4430
- View full text at ACS Publications
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10
Biodiversity impacts of the 2019–2020 Australian megafires

von Driscoll, Don A. ; Macdonald, Kristina J. ; Gibson, Rebecca K. ; et al.

Nature: International weekly journal of science. 635(8040):898-905
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11
Discovery of a Series of Cyclohexylethylamine-Containing Protein Farnesyltransferase Inhibitors Exhibiting Potent Cellular Activity

von Henry, Kenneth J. ; Wasicak, James ; Tasker, Andrew S. ; et al.

Journal of Medicinal Chemistry. 42(23):4844-4852
- View full text at ACS Publications
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12
AusTraits, a curated plant trait database for the Australian flora

von Falster, Daniel ; Gallagher, Rachael ; Wenk, Elizabeth H. ; et al.

Scientific Data. 8(1)
- Zum Volltext in PubMed Central
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13
Second-Generation Peptidomimetic Inhibitors of Protein Farnesyltransferase Demonstrating Improved Cellular Potency and Significant in Vivo Efficacy

von O'Connor, Stephen J. ; Barr, Kenneth J. ; Wang, Le ; et al.

Journal of Medicinal Chemistry. 42(18):3701-3710
- View full text at ACS Publications
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14
Pyrrolidine-3-carboxylic Acids as Endothelin Antagonists. 4. Side Chain Conformational Restriction Leads to ETB Selectivity

von von Geldern, Thomas W. ; Tasker, Andrew S. ; Sorensen, Bryan K. ; et al.

Journal of Medicinal Chemistry. 42(18):3668-3678
- View full text at ACS Publications
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15
Potent and Selective Non-Benzodioxole-Containing Endothelin-A Receptor Antagonists

von Tasker, Andrew S. ; Sorensen, Bryan K. ; Jae, Hwan-Soo ; et al.

Journal of Medicinal Chemistry. 40(3):322-330
- View full text at ACS Publications
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16
2,4-Diarylpyrrolidine-3-carboxylic AcidsPotent ETA Selective Endothelin Receptor Antagonists. 1. Discovery of A-127722

von Winn, Martin ; von Geldern, Thomas W. ; Opgenorth, Terry J. ; et al.

Journal of Medicinal Chemistry. 39(5):1039-1048
- View full text at ACS Publications
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17
Motesanib inhibits Kit mutations associated with gastrointestinal stromal tumors

von Tasker Andrew S ; Manoukian Raffi ; Juan Todd ; et al.

Journal of Experimental & Clinical Cancer Research, Vol 29, Iss 1, p 96 (2010)

Schlagworte: Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
- View full text via DOI
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18
Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

von Weiss, Scott L. ; Peters, Mark J. ; Alhazzani, Waleed ; et al.

Intensive Care Medicine. 46(Suppl 1):1-9
- Zum Volltext (via ReDI)
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19
Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

von Weiss, Scott L. ; Peters, Mark J. ; Alhazzani, Waleed ; et al.

Intensive Care Medicine. 46(Suppl 1):10-67
- Zum Volltext (via ReDI)
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20
Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors

von Cee, Victor J. ; Chavez, Frank, Jr. ; Herberich, Bradley ; et al.

ACS Medicinal Chemistry Letters. 7(4):408-412
- View full text at ACS Publications
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21
Oxopyrido[2,3‑d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors

von Wurz, Ryan P. ; Pettus, Liping H. ; Ashton, Kate ; et al.

ACS Medicinal Chemistry Letters. 6(9):987-992
- View full text at ACS Publications
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22
Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability

von Harrington, Paul E. ; Biswas, Kaustav ; Malwitz, David ; et al.

ACS Medicinal Chemistry Letters. 6(1):68-72
- View full text at ACS Publications
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23
Endothelin Receptors and Receptor Antagonists

von Tasker, Andrew S. ; Pollock, David M. ; Pollock, David M., editor ; et al.

Endothelin Receptors and Signaling Mechanisms. :3-15
- Volltextverfügbarkeit prüfen (via ReDI)
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24
3-Amino-7-phthalazinylbenzoisoxazoles as a Novel Class of Potent, Selective, and Orally Available Inhibitors of p38α Mitogen-Activated Protein Kinase; 3-Amino-7-phthalazinylbenzoisoxazoles

von Pettus, Liping H. ; Xu, Shimin ; Cao, Guo-Qiang ; et al.

Journal of Medicinal Chemistry. 51(20):6280-6292
- View full text at ACS Publications
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25
Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold; p38 Inhibitors Based on a Phthalazine Scaffold

von Herberich, Brad ; Cao, Guo-Qiang ; Chakrabarti, Partha P. ; et al.

Journal of Medicinal Chemistry. 51(20):6271-6279
- View full text at ACS Publications
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