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1
Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

von Lin, Benjamin ; Shelton, Abigail K. ; Smithberger, Erin ; et al.

Acta Neuropathologica Communications. 13(1)
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2
Altered glia-neuron communication in Alzheimer’s Disease affects WNT, p53, and NFkB Signaling determined by snRNA-seq

von Soelter, Tabea M. ; Howton, Timothy C. ; Clark, Amanda D. ; et al.

Cell Communication and Signaling. 22(1)
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3
Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage

von Emma F. Jones ; Timothy C. Howton ; Victoria L. Flanary ; et al.

Molecular Brain, Vol 17, Iss 1, Pp 1-16 (2024)

Schlagworte: Long-read RNA sequencing; Brain; Sex; Transcript usage; Isoform usage; Neurology. Diseases of the nervous system; RC346-429
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4
Signature reversion of three disease‐associated gene signatures prioritizes cancer drug repurposing candidates

von Jennifer L. Fisher ; Elizabeth J. Wilk ; Vishal H. Oza ; et al.

FEBS Open Bio, Vol 14, Iss 5, Pp 803-830 (2024)

Schlagworte: cancer; drug repurposing; gene signature; glioblastoma; transcriptomic signature; Biology (General); QH301-705.5
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5
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6
Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion

von Elizabeth J. Wilk ; Timothy C. Howton ; Jennifer L. Fisher ; et al.

Molecular Medicine, Vol 29, Iss 1, Pp 1-21 (2023)

Schlagworte: Polycystic kidney disease; PKD; ADPKD; Drug repurposing; Signature reversion; LINCS; Therapeutics. Pharmacology; RM1-950; Biochemistry; QD415-436
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7
The landscape of SETBP1 gene expression and transcription factor activity across human tissues.

von Jordan H Whitlock ; Elizabeth J Wilk ; Timothy C Howton ; et al.

PLoS ONE, Vol 19, Iss 1, p e0296328 (2024)

Schlagworte: Medicine; Science
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10
Ten simple rules for using public biological data for your research.

von Vishal H Oza ; Jordan H Whitlock ; Elizabeth J Wilk ; et al.

PLoS Computational Biology, Vol 19, Iss 1, p e1010749 (2023)

Schlagworte: Biology (General); QH301-705.5
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11
Additional file 1 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

von Benjamin Lin ; Abigail K. Shelton ; Erin Smithberger ; et al.

Schlagworte: Biochemistry; Medicine; Genetics; Pharmacology; Biotechnology; Marine Biology; Cancer; Hematology; Virology; Computational Biology; Biological Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; EGFR; Glioblastoma; Synthetic lethality; Kinome rewiring; Upfront combinatorial therapy
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12
Additional file 2 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

von Benjamin Lin ; Abigail K. Shelton ; Erin Smithberger ; et al.

Schlagworte: Biochemistry; Medicine; Genetics; Pharmacology; Biotechnology; Marine Biology; Cancer; Hematology; Virology; Computational Biology; Biological Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; EGFR; Glioblastoma; Synthetic lethality; Kinome rewiring; Upfront combinatorial therapy
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13
Additional file 3 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

von Benjamin Lin ; Abigail K. Shelton ; Erin Smithberger ; et al.

Schlagworte: Biochemistry; Medicine; Genetics; Pharmacology; Biotechnology; Marine Biology; Cancer; Hematology; Virology; Computational Biology; Biological Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; EGFR; Glioblastoma; Synthetic lethality; Kinome rewiring; Upfront combinatorial therapy
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14
Additional file 5 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

von Benjamin Lin ; Abigail K. Shelton ; Erin Smithberger ; et al.

Schlagworte: Biochemistry; Medicine; Genetics; Pharmacology; Biotechnology; Marine Biology; Cancer; Hematology; Virology; Computational Biology; Biological Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; EGFR; Glioblastoma; Synthetic lethality; Kinome rewiring; Upfront combinatorial therapy
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15
Additional file 6 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

von Benjamin Lin ; Abigail K. Shelton ; Erin Smithberger ; et al.

Schlagworte: Biochemistry; Medicine; Genetics; Pharmacology; Biotechnology; Marine Biology; Cancer; Hematology; Virology; Computational Biology; Biological Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; EGFR; Glioblastoma; Synthetic lethality; Kinome rewiring; Upfront combinatorial therapy
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16
Additional file 7 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

von Benjamin Lin ; Abigail K. Shelton ; Erin Smithberger ; et al.

Schlagworte: Biochemistry; Medicine; Genetics; Pharmacology; Biotechnology; Marine Biology; Cancer; Hematology; Virology; Computational Biology; Biological Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; EGFR; Glioblastoma; Synthetic lethality; Kinome rewiring; Upfront combinatorial therapy
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17
Additional file 8 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

von Benjamin Lin ; Abigail K. Shelton ; Erin Smithberger ; et al.

Schlagworte: Biochemistry; Medicine; Genetics; Pharmacology; Biotechnology; Marine Biology; Cancer; Hematology; Virology; Computational Biology; Biological Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; EGFR; Glioblastoma; Synthetic lethality; Kinome rewiring; Upfront combinatorial therapy
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18
Additional file 9 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

von Benjamin Lin ; Abigail K. Shelton ; Erin Smithberger ; et al.

Schlagworte: Biochemistry; Medicine; Genetics; Pharmacology; Biotechnology; Marine Biology; Cancer; Hematology; Virology; Computational Biology; Biological Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; EGFR; Glioblastoma; Synthetic lethality; Kinome rewiring; Upfront combinatorial therapy
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19
Additional file 4 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

von Benjamin Lin ; Abigail K. Shelton ; Erin Smithberger ; et al.

Schlagworte: Biochemistry; Medicine; Genetics; Pharmacology; Biotechnology; Marine Biology; Cancer; Hematology; Virology; Computational Biology; Biological Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; EGFR; Glioblastoma; Synthetic lethality; Kinome rewiring; Upfront combinatorial therapy
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20
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21
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22
Signature reversion of three disease‐associated gene signatures prioritizes cancer drug repurposing candidates.

von Fisher, Jennifer L. ; Wilk, Elizabeth J. ; Oza, Vishal H. ; et al.

FEBS Open Bio. May2024, Vol. 14 Issue 5, p803-830. 28p.

Schlagworte: Drug repositioning; Antineoplastic agents; Brain tumors; Drug approval; Genes
- Zum Volltext in PubMed Central
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23
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24
Publisher Correction: An extracellular network of Arabidopsis leucine-rich repeat receptor kinases

von Smakowska-Luzan, Elwira ; Mott, G. Adam ; Parys, Katarzyna ; et al.

Nature: International weekly journal of science. 561(7722):E8-E8
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25
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