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Treffer 1 - 19 von 19, Suchdauer: 0.89s

1
Synthesis of a HDAC inhibitor–nanogold probe for cryo-EM visualization in class I HDAC co-repressor complexes

von Wiktoria A. Pytel ; John W. R. Schwabe ; James T. Hodgkinson

Beilstein Journal of Organic Chemistry, Vol 22, Iss 1, Pp 480-485 (2026)

Schlagworte: ci-994; co-repressor complex; corest; cryo-em; gold nanoparticle; hdac; Science; Organic chemistry; QD241-441
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2
Sex and other predictors of mortality in long-term follow-up of patients with cardiovascular disease and COVID-19: a single-center retrospective study

von Kocowska-Trytko, Maryla ; Terlecki, Michał ; Olszanecka, Agnieszka ; et al.

Scientific Reports. 15(1)
- Zum Volltext in PubMed Central
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3
The Allosteric Regulator Inositol Phosphate Dramatically Affects the Efficacy and Selectivity of Inhibitors for Different HDAC Complexes

von Pytel, Wiktoria A. ; Patel, Urvashi ; Smalley, Joshua P. ; et al.

Journal of the American Chemical Society. 147(40):36044-36052
- View full text at ACS Publications
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4
Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells

von Smalley, Joshua P. ; Baker, India M. ; Pytel, Wiktoria A. ; et al.

Journal of Medicinal Chemistry. 65(7):5642-5659
- View full text at ACS Publications
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5
The Allosteric Regulator Inositol Phosphate Dramatically Affects the Efficacy and Selectivity of Inhibitors for Different HDAC Complexes

von Wiktoria A Pytel ; Urvashi Patel ; Joshua P Smalley ; et al.

Schlagworte: Chemical sciences; Engineering; Inhibition; Inhibitors; Peptides and proteins; Phosphates; Selectivity
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6
Understanding and Managing Atopic Dermatitis: Insights into Pathogenesis and Treatment Strategies

von Kamila Szewczyk ; Bartlomiej Szewczyk ; Paulina Pytel ; et al.

Quality in Sport, Vol 22 (2024)

Schlagworte: atopic dermatitis; immune dysregulation; JAK inhibitors; calcineurin inhibitors; atopic dermatitis treatment; Sports; GV557-1198.995; Sports medicine; RC1200-1245
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7
The Skin's Sun Story: Risks and Precautions

von Wiktoria Julia Krzesłowska ; Kamila Szewczyk ; Paulina Pytel ; et al.

Quality in Sport, Vol 22 (2024)

Schlagworte: solar exposure and skin; solar radiation; vitamin d; sunscreen; photoprotection; photodermatoses; Sports; GV557-1198.995; Sports medicine; RC1200-1245
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8
Respiratory syncytial virus - current treatment options and future possibilities for prophylaxis

von Weronika Hołownia ; Kamila Szewczyk ; Bartłomiej Szewczyk ; et al.

Journal of Education, Health and Sport, Vol 74 (2024)

Schlagworte: RSV pathogenesis; RSV treatment; RSV prophylaxis; RSV epidemiology; Education; Sports; GV557-1198.995; Medicine
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9
Physical Activity as a Trigger for Anaphylaxis: Understanding Food-Dependent Exercise-Induced Anaphylaxis

von Kamila Szewczyk ; Bartłomiej Szewczyk ; Weronika Hołownia ; et al.

Journal of Education, Health and Sport, Vol 74 (2024)

Schlagworte: food-dependent exercise induced anaphylaxis; exercise induced-anaphylaxis; food allergies; pathogenesis of FDEIA; diagnosis of FDEIA; sport and anaphylaxis; Education; Sports; GV557-1198.995; Medicine
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10
Health consequences of Obstructive Sleep Apnoea Syndrome

von Kamila Szewczyk ; Bartłomiej Szewczyk ; Wiktoria Julia Krzesłowska ; et al.

Journal of Education, Health and Sport, Vol 74 (2024)

Schlagworte: Obstructive sleep apnoea; Obstructive sleep apnoea pathophysiology; Obstructive sleep apnoea complications; Obstructive sleep apnoea epidemiology; Cardiovascular consequences of Obstructive Sleep Apnoea; Obstructive sleep apnoea treatment; Education; Sports; GV557-1198.995; Medicine
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11
Biologic Therapies: Targeting Severe Asthma at the Molecular Level

von Kamila Szewczyk ; Bartłomiej Szewczyk ; Wiktoria Julia Krzesłowska ; et al.

Journal of Education, Health and Sport, Vol 74 (2024)

Schlagworte: biologic agents for asthma; omalizumab; mepolizumab; bernalizumab; tezepelumab; monoclonal antibodies; Education; Sports; GV557-1198.995; Medicine
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12
Folliculitis Decalvans: A Review of Current Treatment Modalities

von Wiktoria Julia ; Kamila Szewczyk ; Paulina Pytel ; et al.

Journal of Education, Health and Sport, Vol 70 (2024)

Schlagworte: folliculitis decalvans; folliculitis decalvans treatment; cicatricial alopecia; s.aureus; alopecia treatment; Education; Sports; GV557-1198.995; Medicine
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13
Clinical Frailty Scale - frailty assessment and rehabilitation potential

von Szymon Wiśniewski ; Weronika Hołownia ; Wiktoria Julia Krzesłowska ; et al.

Journal of Education, Health and Sport, Vol 71 (2024)

Schlagworte: Geriatric Medicine; Ambulatory Care; Clinical Frailty Scale; Frailty; CFS; Education; Sports; GV557-1198.995; Medicine
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14
Urinalysis in primary care doctor practice

von Bartlomiej Szewczyk ; Kamila Szewczyk ; Paulina Pytel ; et al.

Journal of Education, Health and Sport, Vol 70 (2024)

Schlagworte: Urinalysis; Urine sediment; Urinary tract infection; Education; Sports; GV557-1198.995; Medicine
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15
Cereblon-recruiting proteolysis targeting chimeras (PROTACs) can determine the selective degradation of HDAC1 over HDAC3

von Aline R Pavan ; Joshua P Smalley ; Urvashi Patel ; et al.

Schlagworte: Chemical sciences; Engineering; Uncategorised value
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16
A 'click' chemistry approach to novel entinostat (MS-275) based class I histone deacetylase proteolysis targeting chimeras

von Jasmine M Cross ; Megan E Coulson ; Joshua P Smalley ; et al.

Schlagworte: Science & Technology; Life Sciences & Biomedicine; Biochemistry & Molecular Biology; Chemistry; Medicinal; Pharmacology & Pharmacy; DEGRADATION; HDAC1
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17
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18
Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells

von Joshua P Smalley ; India M Baker ; Wiktoria A Pytel ; et al.

Schlagworte: Degradation; Peptides and proteins; Ligands; Genetics; Inhibitors
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19
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