1
The PRIMED Consortium: Reducing disparities in polygenic risk assessment.

von Kullo, IJ ; Conomos, MP ; Nelson, SC ; et al.

Schlagworte: diversity; equity; polygenic risk score; Humans; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Multifactorial Inheritance; Neoplasms; Phenotype; Risk Assessment; Risk Factors
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2
Genetic analysis of lung cancer and the germline impact on somatic mutation burden

von Gabriel, AAG ; Atkins, JR ; Penha, RCC ; et al.
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3
Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry.

von Chen, F ; Madduri, RK ; Rodriguez, AA ; et al.

Schlagworte: African ancestry; Aggressive prostate cancer; Polygenic risk score; Prostate cancer; Susceptibility loci
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4
Genetic factors associated with prostate cancer conversion from active surveillance to treatment

von Jiang, Y ; Meyers, TJ ; Emeka, AA ; et al.
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5
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

von Conti, DV ; Darst, BF ; Moss, LC ; et al.

Conti, DV, Darst, BF, Moss, LC, Saunders, EJ, Sheng, X, Chou, A, Schumacher, FR, Al Olama, A A, Benlloch, S, Dadaev, T, Brook, MN, Sahimi, A, Hoffmann, TJ, Takahashi, A, Matsuda, K, Momozawa, Y, Fujita, M, Muir, K, Lophatananon, A, Wan, P, Le Marchand, L, Wilkens, LR, Stevens, V L, Gapstur, SM, Carter, BD, Schleutker, J, Tammela, TL, Sipeky, C, Auvinen, A, Giles, GG, Southey, MC, MacInnis, R J, Cybulski, C, Woko?orczyk, D, Lubi?ski, J, Neal, DE, Donovan, JL, Hamdy, FC, Martin, RM, Nordestgaard, BG, Nielsen, SF, Weischer, M, Bojesen, SE, Røder, MA, Iversen, P, Batra, J, Chambers, S, ....

Schlagworte: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCOR01; name=EMC OR-01; /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being; name=SDG 3 - Good Health and Well-being
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6
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

von Kachuri L ; Johansson M ; Rashkin SR ; et al.

Nature Communications, 1 December 2020
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7
Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in over 140,000 European Descendants

von Wu, L ; Wang, J ; Cai, Q ; et al.

Cancer Research , 79 (13) pp. 3192-3204. (2019)
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8
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

von Kachuri, L ; Johansson, M ; Rashkin, SR ; et al.

Schlagworte: England
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9
Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy

von Asai, Y ; Eslami, A ; van Ginkel, CD ; et al.

Asai, Y, Eslami, A, van Ginkel, CD, Akhabir, L, Wan, M, Ellis, G, Ben-Shoshan, M, Martino, D, Ferreira, MA, Allen, K, Mazer, B, de Groot, H, de Jong, N, Gerth van Wijk, R, Dubois, AEJ, Chin, R, Cheuk, S, Hoffman, J, Jorgensen, E, Witte, JS, Melles, RB, Hong, XM, Wang, XB, Hui, J, Musk, AW, Hunter, M, James, AL, Koppelman, GH, Sandford, AJ, Clarke, AE & Daley, D 2018, 'Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy', Journal of Allergy and Clinical ....

Schlagworte: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCOR013907; name=EMC OR-01-39-07
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10
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

von Gusev, A ; Shi, H ; Kichaev, G ; et al.
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11
Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

von Conti, DV ; Wang, K ; Sheng, X ; et al.

Schlagworte: PRACTICAL/ELLIPSE Consortium; Chromosomes; Human; Pair 13; Pair 22; Humans; Prostatic Neoplasms; Genetic Predisposition to Disease; Case-Control Studies; Gene Frequency; Polymorphism; Single Nucleotide; African Continental Ancestry Group; Male; Genome-Wide Association Study; Insulin Receptor Substrate Proteins; Genetic Loci; Checkpoint Kinase 2
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12
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

von Wang, A ; Shen, J ; Rodriguez, AA ; et al.
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13
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

von Gusev, A ; Shi, H ; Kichaev, G ; et al.
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14
Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome

von Matthay, Michael ; Liu, Kathleen ; Sapru, Anil ; et al.
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15
Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: A systematic review and meta-analysis

von Witte, John ; Weng, PH ; Huang, YL ; et al.
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16
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

von Lee, SH ; Ripke, S ; Neale, BM ; et al.

NATURE GENETICS ; ISSN: 1061-4036

Schlagworte: Social Sciences; MAJOR DEPRESSIVE DISORDER; AUTISM SPECTRUM DISORDERS; DEFICIT HYPERACTIVITY DISORDER; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; COMMON SNPS; BIPOLAR DISORDER; CROHNS-DISEASE; SCHIZOPHRENIA; RISK; ASSOCIATION
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17
Mechanistic phenotypes: An aggregative phenotyping strategy to identify disease mechanisms using GWAS data

von Witte, John ; Mosley, JD ; Van, SL ; et al.
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18
Association of the Innate Immunity and Inflammation Pathway with Advanced Prostate Cancer Risk

von Witte, John ; Kazma, R ; Mefford, JA ; et al.
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19
The Covariate's Dilemma

von Witte, John ; Mefford, J ; Witte, JS
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20
Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer

von Byun, J ; Han, Y ; Li, Y ; et al.
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21
Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: A systematic review and meta-analysis

von Weng, PH ; Huang, YL ; Page, JH ; et al.
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22
Hypospadias and variants in genes related to sex hormone biosynthesis and metabolism

von Carmichael, SL ; Witte, JS ; Ma, C ; et al.

Andrology, vol 2, iss 1

Schlagworte: 3215 Reproductive Medicine (for-2020); 32 Biomedical and Clinical Sciences (for-2020); 3202 Clinical Sciences (for-2020); Genetics (rcdc); 17-Hydroxysteroid Dehydrogenases (mesh); 3-Oxo-5-alpha-Steroid 4-Dehydrogenase (mesh); Carrier Proteins (mesh); Cytochrome P-450 CYP3A (mesh); Genetic Predisposition to Disease (mesh); Genetic Variation (mesh); Genotype (mesh); Gonadal Steroid Hormones (mesh); Humans (mesh); Hypospadias (mesh); Male (mesh); Membrane Proteins (mesh); Multienzyme Complexes (mesh); Penis (mesh); Polymorphism; Single Nucleotide (mesh); Progesterone Reductase (mesh); Risk (mesh); Steroid Isomerases (mesh); Steryl-Sulfatase (mesh); gene polymorphism; hypospadias; sex hormones
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23
Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance)

von Chhibber, A ; Mefford, J ; Stahl, EA ; et al.

Pharmacogenomics Journal, vol 14, iss 4

Schlagworte: Pharmacology and Pharmaceutical Sciences; Pharmacology & Pharmacy
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24
Association of CYP2C9*2 With Bosentan‐Induced Liver Injury

von Markova, SM ; De Marco, T ; Bendjilali, N ; et al.

Clinical Pharmacology & Therapeutics, vol 94, iss 6

Schlagworte: 3214 Pharmacology and Pharmaceutical Sciences (for-2020); 32 Biomedical and Clinical Sciences (for-2020); Digestive Diseases (rcdc); Chronic Liver Disease and Cirrhosis (rcdc); Liver Disease (rcdc); Genetics (rcdc); Rare Diseases (rcdc); Clinical Research (rcdc); 2.1 Biological and endogenous factors (hrcs-rac); Alanine Transaminase (mesh); Aryl Hydrocarbon Hydroxylases (mesh); Aspartate Aminotransferases (mesh); Bosentan (mesh); Chemical and Drug Induced Liver Injury (mesh); Cytochrome P-450 CYP2C9 (mesh); Endothelin Receptor Antagonists (mesh); Female (mesh); Genetic Association Studies (mesh); Genetic Markers (mesh); HEK293 Cells (mesh); Humans (mesh); Hypertension; Pulmonary (mesh); Liver-Specific Organic Anion Transporter 1 (mesh); Male (mesh); Middle Aged (mesh); Multidrug Resistance-Associated Protein 2 (mesh); Organic Anion Transporters (mesh); Polymorphism; Single Nucleotide (mesh)
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25
Does a family history of prostate cancer result in more aggressive disease?

von Klein, EA ; Kupelian, PA ; Witte, JS

Prostate Cancer and Prostatic Diseases. 1(6):297-300
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