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Treffer 1 - 25 von 2088, Suchdauer: 1.09s

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1
Addressing Atropisomerism in the Development of Sotorasib, a Covalent Inhibitor of KRAS G12C: Structural, Analytical, and Synthetic Considerations

von Lanman, Brian A. ; Parsons, Andrew T. ; Zech, Stephan G.

Accounts of Chemical Research. 55(20):2892-2903
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2
Creating a more strategic small molecule biophysical hit characterization workflow

von Fotsch, Christopher ; Basu, Debaleena ; Case, Ryan ; et al.

In SLAS Discovery June 2024 29(4)
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3
Science with the Cherenkov Telescope Array

von Consortium, The Cherenkov Telescope Array ; Acharya, B. S. ; Agudo, I. ; et al.

Schlagworte: Astrophysics - Instrumentation and Methods for Astrophysics; Astrophysics - High Energy Astrophysical Phenomena; High Energy Physics - Experiment
- View full text via Arxiv
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4
Cherenkov Telescope Array Contributions to the 35th International Cosmic Ray Conference (ICRC2017)

von Acero, F. ; Acharya, B. S. ; Portella, V. Acín ; et al.

Schlagworte: Astrophysics - High Energy Astrophysical Phenomena
- View full text via Arxiv
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5
Prospects for CTA observations of the young SNR RX J1713.7-3946

von Consortium, The CTA ; Acero, F. ; Aloisio, R. ; et al.

The Astrophysical Journal, Volume 840, Number 2 (2017) p. 74

Schlagworte: Astrophysics - High Energy Astrophysical Phenomena
- View full text via Arxiv
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6
Contributions of the Cherenkov Telescope Array (CTA) to the 6th International Symposium on High-Energy Gamma-Ray Astronomy (Gamma 2016)

von Consortium, The CTA ; Abchiche, A. ; Abeysekara, U. ; et al.

Schlagworte: Astrophysics - High Energy Astrophysical Phenomena
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7
Inauguration and First Light of the GCT-M Prototype for the Cherenkov Telescope Array

von Watson, J. J. ; De Franco, A. ; Abchiche, A. ; et al.

Schlagworte: Astrophysics - Instrumentation and Methods for Astrophysics; Astrophysics - High Energy Astrophysical Phenomena
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8
The Gamma-ray Cherenkov Telescope for the Cherenkov Telescope Array

von Tibaldo, L. ; Abchiche, A. ; Allan, D. ; et al.

AIP Conference Proceedings 1792, 080004 (2017)

Schlagworte: Astrophysics - Instrumentation and Methods for Astrophysics; Astrophysics - High Energy Astrophysical Phenomena
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9
Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery

von Zech, Stephan G. ; Kohlmann, Anna ; Zhou, Tianjun ; et al.

Journal of Medicinal Chemistry. 59(2):671-686
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10
The GCT camera for the Cherenkov Telescope Array

von Brown, Anthony M. ; Abchiche, A. ; Allan, D. ; et al.

Schlagworte: Astrophysics - Instrumentation and Methods for Astrophysics
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11
Fragment Growing and Linking Lead to Novel Nanomolar Lactate Dehydrogenase Inhibitors

von Kohlmann, Anna ; Zech, Stephan G. ; Li, Feng ; et al.

Journal of Medicinal Chemistry. 56(3):1023-1040
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12
Protein Binding to Lanthanide(III) Complexes Can Reduce the Water Exchange Rate at the Lanthanide

von Zech, Stephan G. ; Eldredge, Harriet B. ; Lowe, Mark P. ; et al.

Inorganic Chemistry. 46(9):3576-3584
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13
Protein Structure Determination by High-Resolution Solid-State NMR Spectroscopy: Application to Microcrystalline Ubiquitin

von Zech, Stephan G. ; Wand, A. Joshua ; McDermott, Ann E.

Journal of the American Chemical Society. 127(24):8618-8626
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14
Discovery of mobocertinib, a potent, oral inhibitor of EGFR exon 20 insertion mutations in non–small cell lung cancer

von Huang, Wei-Sheng ; Li, Feng ; Gong, Yongjin ; et al.

Bioorganic & Medicinal Chemistry Letters ; volume 80, page 129084 ; ISSN 0960-894X
- View full text via BASE
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15
Characterization of Protein−Ligand Interactions by High-Resolution Solid-State NMR Spectroscopy

von Zech, Stephan G. ; Olejniczak, Edward ; Hajduk, Philip ; et al.

Journal of the American Chemical Society. 126(43):13948-13953
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16
Ionic States of Substrates and Transition State Analogues at the Catalytic Sites of N-Ribosyltransferases †

von Sauve, Anthony A. ; Cahill, Sean M. ; Zech, Stephan G. ; et al.

Biochemistry. 42(19):5694-5705
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17
Orientation and Protein−Cofactor Interactions of Monosubstituted n-Alkyl Naphthoquinones in the A1 Binding Site of Photosystem I

von Pushkar, Yulia N. ; Zech, Stephan G. ; Stehlik, Dietmar ; et al.

The Journal of Physical Chemistry B. 106(46):12052-12058
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18
A Structural Model for the Charge Separated State in Photosystem I from the Orientation of the Magnetic Interaction Tensors

von Zech, Stephan G. ; Hofbauer, Wulf ; Kamlowski, Andreas ; et al.

The Journal of Physical Chemistry B. 104(41):9728-9739
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19
The Quinone Acceptor A1 in Photosystem I: Binding Site, and Comparison to QA in Purple Bacteria Reaction Centers

von Kamlowski, Andreas ; Altenberg-Greulich, Brigitte ; van der Est, Arthur ; et al.

The Journal of Physical Chemistry B. 102(42):8278-8287
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20
The Radical Pair State in Photosystem I Single Crystals: Orientation Dependence of the Transient Spin-Polarized EPR Spectra

von Kamlowski, Andreas ; Zech, Stephan G. ; Fromme, Petra ; et al.

The Journal of Physical Chemistry B. 102(42):8266-8277
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21
Measurement of Cofactor Distances between P700 •+ and A1 •- in Native and Quinone-Substituted Photosystem I Using Pulsed Electron Paramagnetic Resonance Spectroscopy †

von Zech, Stephan G. ; van der Est, Arthur J. ; Bittl, Robert

Biochemistry. 36(32):9774-9779
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22
Pulsed EPR Study of Spin-Coupled Radical Pairs in Photosynthetic Reaction Centers: Measurement of the Distance Between and in Photosystem I and between and in Bacterial Reaction Centers

von Bittl, Robert ; Zech, Stephan G.

The Journal of Physical Chemistry. 101(8):1429-1436
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23
Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors

von Lanman, Brian A. ; Allen, Jennifer R. ; Allen, John G. ; et al.

Journal of Medicinal Chemistry. 63(1):52-65
- View full text at ACS Publications
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24
Light-induced changes in transient EPR spectra of P865 +.QA -.

von Bittl, Robert ; Zech, Stephan G. ; Lubitz, Wolfgang ; et al.

The Reaction Center of Photosynthetic Bacteria : Structure and Dynamics. :333-339
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25
EP-2104R: A Fibrin-Specific Gadolinium-Based MRI Contrast Agent for Detection of Thrombus; EP-2104R: Thrombus Specific MRI Contrast Agent

von Overoye-Chan, Kirsten ; Koerner, Steffi ; Looby, Richard J. ; et al.

Journal of the American Chemical Society. 130(18):6025-6039
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